|
|
eF-site ID
|
134l-A |
|
PDB Code
|
134l |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
ROLE OF ARG 115 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME. X-RAY STRUCTURE OF HIS 115 AND GLU 115 MUTANTS |
|
Classification
|
HYDROLASE(O-GLYCOSYL) |
|
Compound
|
HUMAN LYSOZYME |
|
Source
|
Homo sapiens (Human) (LYSC_HUMAN) |
|
|
Sequence
|
A: |
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNT
RATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLS
CSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNECQNRD
VRQYVQGCGV
|
|
|
Description
|
(1) |
LYSOZYME (E.C.3.2.1.17) MUTANT WITH ARG 115 REPLACED BY GLU (R115E)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
77-95 |
| type |
prosite |
| sequence |
CHLSCSALLQDNIADAVAC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC
|
| source |
prosite : PS00128
|
|
|
2)
|
chain |
A |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
53 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|