eF-site ID 102d-AB
PDB Code 102d
Chain A, B

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Title SEQUENCE-DEPENDENT DRUG BINDING TO THE MINOR GROOVE OF DNA: THE CRYSTAL STRUCTURE OF THE DNA DODECAMER D(CGCAAATTTGCG)2 COMPLEXED WITH PROPAMIDINE
Classification DNA
Compound DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3')
Source (102D)
Sequence A:  CGCAAATTTGCG
B:  CGCAAATTTGCG
Description (1)  5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3', PROPAMIDINE


Functional site

1) chain A
residue 6
type
ligand
sequence A
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

2) chain A
residue 7
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

3) chain A
residue 8
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

4) chain A
residue 9
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

5) chain A
residue 10
type
ligand
sequence G
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

6) chain B
residue 18
type
ligand
sequence A
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

7) chain B
residue 19
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

8) chain B
residue 20
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

9) chain B
residue 21
type
ligand
sequence T
description BINDING SITE FOR RESIDUE TNT B 25
source : AC1

10) chain A
residue 5-10
type binding
ligand TNT: 1,3-BIS(AMIDINOPHENOXY)PROPANE
sequence AATTTG
description 1,3-BIS(AMIDINOPHENOXY)PROPANE binding site
source pdb_hetatom : TNT_102d_B_25

11) chain B
residue 16-21
type binding
ligand TNT: 1,3-BIS(AMIDINOPHENOXY)PROPANE
sequence AAATTT
description 1,3-BIS(AMIDINOPHENOXY)PROPANE binding site
source pdb_hetatom : TNT_102d_B_25


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