FB8

4 PDB entries

6GU3
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CDK1/CYCLINB/CKS2 IN COMPLEX WITH AZD5438
Descriptor:Cyclin-dependent kinase 1, G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2, ...
Authors:Wood, D.J., Korolchuk, S., Tatum, N.J., Wang, L.Z., Endicott, J.A., Noble, M.E.M., Martin, M.P.
Deposit date:2018-06-19
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019
6GU7
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CDK1/CKS2 IN COMPLEX WITH AZD5438
Descriptor:Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine
Authors:Wood, D.J., Korolchuk, S., Tatum, N.J., Wang, L.Z., Endicott, J.A., Noble, M.E.M., Martin, M.P.
Deposit date:2018-06-19
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019
6GUE
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CDK2/CYCLINA IN COMPLEX WITH AZD5438
Descriptor:Cyclin-dependent kinase 2, Cyclin-A2, 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine
Authors:Wood, D.J., Korolchuk, S., Tatum, N.J., Wang, L.Z., Endicott, J.A., Noble, M.E.M., Martin, M.P.
Deposit date:2018-06-19
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019
6GUH
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CDK2 IN COMPLEX WITH AZD5438
Descriptor:Cyclin-dependent kinase 2, 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine, 1,2-ETHANEDIOL
Authors:Wood, D.J., Korolchuk, S., Tatum, N.J., Wang, L.Z., Endicott, J.A., Noble, M.E.M., Martin, M.P.
Deposit date:2018-06-19
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019