Author results

1M3U
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CRYSTAL STRUCTURE OF KETOPANTOATE HYDROXYMETHYLTRANSFERASE COMPLEXED THE PRODUCT KETOPANTOATE
Descriptor:3-methyl-2-oxobutanoate hydroxymethyltransferase, MAGNESIUM ION, KETOPANTOATE
Authors:von Delft, F., Inoue, T., Saldanha, S.A., Ottenhof, H.H., Dhanaraj, V., Witty, M., Abell, C., Smith, A.G., Blundell, T.L.
Deposit date:2002-06-30
Release date:2003-07-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of E. coli Ketopantoate Hydroxymethyl Transferase Complexed with Ketopantoate and Mg(2+), Solved by Locating 160 Selenomethionine Sites.
Structure, 11, 2003
1IHO
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CRYSTAL APO-STRUCTURE OF PANTOTHENATE SYNTHETASE FROM E. COLI
Descriptor:PANTOATE--BETA-ALANINE LIGASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,2-ETHANEDIOL
Authors:von Delft, F., Lewendon, A., Dhanaraj, V., Blundell, T.L., Abell, C., Smith, A.
Deposit date:2001-04-19
Release date:2001-05-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily.
Structure, 9, 2001
4AYW
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
Descriptor:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
2CMW
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STRUCTURE OF HUMAN CASEIN KINASE 1 GAMMA-1 IN COMPLEX WITH 2-(2- HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE
Descriptor:CASEIN KINASE I ISOFORM GAMMA-1, 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, PHOSPHATE ION, ...
Authors:Bunkoczi, G., Rellos, P., Das, S., Savitsky, P., Niesen, F., Sobott, F., Fedorov, O., Pike, A.C.W., von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Weigelt, J., Knapp, S.
Deposit date:2006-05-15
Release date:2006-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of Human Casein Kinase 1 Gamma-1 in Complex with 2-(2-Hydroxyethylamino)-6-(3-Chloroanilino)-9-Isopropylpurine (Casp Target)
To be Published
2HW5
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THE CRYSTAL STRUCTURE OF HUMAN ENOYL-COENZYME A (COA) HYDRATASE SHORT CHAIN 1, ECHS1
Descriptor:Enoyl-CoA hydratase, MAGNESIUM ION, CROTONYL COENZYME A
Authors:Turnbull, A.P., Salah, E., Niesen, F., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Kavanagh, K., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-07-31
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
To be Published
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
Descriptor:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2006-08-14
Release date:2006-09-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2UZP
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN PROTEIN KINASE C GAMMA.
Descriptor:PROTEIN KINASE C GAMMA TYPE, PYRIDOXAL-5'-PHOSPHATE, COBALT (II) ION, ...
Authors:Pike, A.C.W., Amos, A., Johansson, C., Sobott, F., Savitsky, P., Berridge, G., Fedorov, O., Umeano, C., Gorrec, F., Bunkoczi, G., Debreczeni, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S.
Deposit date:2007-04-30
Release date:2007-05-29
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
2AR7
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CRYSTAL STRUCTURE OF HUMAN ADENYLATE KINASE 4, AK4
Descriptor:Adenylate kinase 4
Authors:Filippakopoulos, P., Turnbull, A.P., Fedorov, O., Weigelt, J., Bunkoczi, G., Ugochukwu, E., Debreczeni, J., Niesen, F., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Structural Genomics Consortium (SGC)
Deposit date:2005-08-19
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of human adenylate kinase 4, AK4
To be Published
2BBW
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CRYSTAL STRUCTURE OF HUMAN ADENYLATE KINASE 4 (AK4) IN COMPLEX WITH DIGUANOSINE PENTAPHOSPHATE
Descriptor:adenylate kinase 4, AK4, DIGUANOSINE-PENTAPHOSPHATE
Authors:Filippakopoulos, P., Turnbull, A.P., Fedorov, O., Weigelt, J., Bunkoczi, G., Ugochukwu, E., Debreczeni, J., Niesen, F., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2005-10-17
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate
To be Published
2BUJ
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CRYSTAL STRUCTURE OF THE HUMAN SERINE-THREONINE KINASE 16 IN COMPLEX WITH STAUROSPORINE
Descriptor:SERINE/THREONINE-PROTEIN KINASE 16, CHLORIDE ION, STAUROSPORINE
Authors:Debreczeni, J.E., Eswaran, J., Bullock, A., Filippakopoulos, P., Kavanagh, K., Amos, A., Fedorov, O., Sobott, F., Ball, L.J., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Knapp, S.
Deposit date:2005-06-13
Release date:2005-07-05
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Human Serine-Threonine Kinase 16 in Complex with Staurosporine
To be Published
2C47
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STRUCTURE OF CASEIN KINASE 1 GAMMA 2
Descriptor:CASEIN KINASE 1 GAMMA 2 ISOFORM, (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, MAGNESIUM ION
Authors:Bunkoczi, G., Rellos, P., Das, S., Ugochukwu, E., Fedorov, O., Sobott, F., Eswaran, J., Amos, A., Ball, L., von Delft, F., Bullock, A., Debreczeni, J., Turnbull, A., Sundstrom, M., Weigelt, J., Arrowsmith, C., Edwards, A., Knapp, S.
Deposit date:2005-10-16
Release date:2005-11-07
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of Casein Kinase 1 Gamma 2
To be Published
2CLS
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THE CRYSTAL STRUCTURE OF THE HUMAN RND1 GTPASE IN THE ACTIVE GTP BOUND STATE
Descriptor:RHO-RELATED GTP-BINDING PROTEIN RHO6, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pike, A.C.W., Yang, X., Colebrook, S., Gileadi, O., Sobott, F., Bray, J., Wen Hwa, L., Marsden, B., Zhao, Y., Schoch, G., Elkins, J., Debreczeni, J.E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2006-04-28
Release date:2006-05-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The Crystal Structure of the Human Rnd1 Gtpase in the Active GTP Bound State
To be Published
2EXE
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATED CLK3
Descriptor:Dual specificity protein kinase CLK3
Authors:Papagrigoriou, E., Rellos, P., Das, S., Bullock, A., Ball, L.J., Turnbull, A., Savitsky, P., Fedorov, O., Johansson, C., Ugochukwu, E., Sobott, F., von Delft, F., Edwards, A., Sundstrom, M., Weigelt, J., Arrowsmith, C., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2005-11-08
Release date:2005-11-15
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the phosphorylated CLK3
TO BE PUBLISHED
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
Descriptor:regulator of G-protein signalling 3 isoform 1, SULFATE ION
Authors:Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-11-28
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
Descriptor:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
Authors:Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-15
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2FV8
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THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATE
Descriptor:Rho-related GTP-binding protein RhoB, GUANOSINE-5'-DIPHOSPHATE
Authors:Turnbull, A.P., Soundararajan, M., Smee, C., Johansson, C., Schoch, G., Gorrec, F., Bray, J., Papagrigoriou, E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-01-30
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of RhoB in the GDP-bound state
To be Published
2GF2
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CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE
Descriptor:3-hydroxyisobutyrate dehydrogenase
Authors:Papagrigoriou, E., Salah, E., Turnbull, A.P., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Gorrec, F., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-03-21
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human hydroxyisobutyrate dehydrogenase
To be Published
2IHC
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CRYSTAL STRUCTURE OF THE BRIC-A-BRAC (BTB) DOMAIN OF HUMAN BACH1
Descriptor:Transcription regulator protein BACH1
Authors:Amos, A.L., Turnbull, A.P., Bunkoczi, G., Papagrigoriou, E., Gorrec, F., Umeano, C., Bullock, A., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2006-09-26
Release date:2006-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of the bric-a-brac (BTB) domain of human BACH1
To be Published
2IIK
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CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL ACETYL-COA ACYL TRANSFERASE 1 (ACAA1)
Descriptor:3-ketoacyl-CoA thiolase, peroxisomal
Authors:Papagrigoriou, E., Johansson, C., Smee, C., Kavanagh, K., Pike, A.C.W., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C.H., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-09-28
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
TO BE PUBLISHED
2IWI
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CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1
Descriptor:SERINE/THREONINE-PROTEIN KINASE PIM-2, RUTHENIUM-PYRIDOCARBAZOLE-1
Authors:Russo, S., Debreczeni, J.E., Amos, A., Bullock, A.N., Fedorov, O., Niesen, F., Sobott, F., Turnbull, A., Pike, A.C.W., Ugochukwu, E., Papagrigoriou, E., Bunkoczi, G., Gorrec, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., von Delft, F., Knapp, S.
Deposit date:2006-06-30
Release date:2006-08-02
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
PLoS ONE, 4, 2009
2JAM
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G, POLYPEPTIDE, 1,2-ETHANEDIOL, ...
Authors:Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
Deposit date:2006-11-29
Release date:2007-03-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
To be Published
2NZJ
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THE CRYSTAL STRUCTURE OF REM1 IN COMPLEX WITH GDP
Descriptor:GTP-binding protein REM 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Elkins, J.M., Soundararajan, M., Yang, X., Gorrec, F., Umeano, C., Salah, E., Burgess, N., Johansson, C., Berridge, G., Gileadi, O., Bray, J., Marsden, B., Watts, S., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-11-23
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of REM1 in complex with GDP
To be Published
2NZL
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CRYSTAL STRUCTURE OF HUMAN HYDROXYACID OXIDASE 1
Descriptor:Hydroxyacid oxidase 1, FLAVIN MONONUCLEOTIDE, GLYOXYLIC ACID
Authors:Ugochukwu, E., Kavanagh, K., Pilka, E., Berridge, G., Debreczeni, J.E., Papagrigoriou, E., Turnbull, A., Niesen, F., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-11-24
Release date:2006-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of human hydroxyacid oxidase 1
To be Published
2OVJ
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC GTPASE ACTIVATING PROTEIN 1 (RACGAP1) MGCRACGAP.
Descriptor:Rac GTPase-activating protein 1, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
Authors:Shrestha, L., Papagrigoriou, E., Soundararajan, M., Elkins, J., Johansson, C., von Delft, F., Pike, A.C.W., Burgess, N., Turnbull, A., Debreczeni, J., Gorrec, F., Umeano, C., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-14
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
Descriptor:Ezrin-radixin-moesin-binding phosphoprotein 50
Authors:Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-26
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published