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2Y3V
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BU of 2y3v by Molmil
N-terminal head domain of Danio rerio SAS-6
Descriptor: SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG
Authors:van Breugel, M.
Deposit date:2010-12-27
Release date:2011-02-09
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structures of SAS-6 suggest its organization in centrioles.
Science, 331, 2011
2Y3W
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BU of 2y3w by Molmil
N-terminal head domain and beginning of coiled coil domain of Danio rerio SAS-6
Descriptor: SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG
Authors:van Breugel, M.
Deposit date:2010-12-27
Release date:2011-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of SAS-6 suggest its organization in centrioles.
Science, 331, 2011
4CKM
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BU of 4ckm by Molmil
Structure of the N-terminal domain of Leishmania SAS-6
Descriptor: GLYCEROL, MAGNESIUM ION, SAS-6
Authors:van Breugel, M.
Deposit date:2014-01-07
Release date:2014-03-05
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
4CKP
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BU of 4ckp by Molmil
Structure of an N-terminal fragment of Leishmania SAS-6 that contains part of its coiled coil domain
Descriptor: SAS-6
Authors:van Breugel, M.
Deposit date:2014-01-07
Release date:2014-03-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
4CKN
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BU of 4ckn by Molmil
Structure of an N-terminal fragment of Leishmania SAS-6 containing parts of its coiled coil domain, F257E mutant
Descriptor: SAS-6
Authors:van Breugel, M.
Deposit date:2014-01-07
Release date:2014-03-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
7PT5
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BU of 7pt5 by Molmil
Crystal structure of the CH domain of human CEP44
Descriptor: Centrosomal protein of 44 kDa
Authors:Rosa e Silva, I, van Breugel, M.
Deposit date:2021-09-26
Release date:2022-04-06
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural validation and assessment of AlphaFold2 predictions for centrosomal and centriolar proteins and their complexes.
Commun Biol, 5, 2022
7PTB
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BU of 7ptb by Molmil
Crystal structure of the SPD-2 domain of human CEP192
Descriptor: Centrosomal protein of 192 kDa, NITRATE ION
Authors:Rosa e Silva, I, van Breugel, M.
Deposit date:2021-09-26
Release date:2022-04-06
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural validation and assessment of AlphaFold2 predictions for centrosomal and centriolar proteins and their complexes.
Commun Biol, 5, 2022
5LPI
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BU of 5lpi by Molmil
Structure of the zinc finger array of Cep104
Descriptor: Centrosomal protein of 104 kDa, ZINC ION
Authors:van Breugel, M, Yu, M, al Jassar, C.
Deposit date:2016-08-13
Release date:2017-01-11
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
5LPH
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BU of 5lph by Molmil
Structure of the TOG domain of human Cep104
Descriptor: Centrosomal protein of 104 kDa
Authors:van Breugel, M.
Deposit date:2016-08-13
Release date:2017-01-11
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
5OID
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BU of 5oid by Molmil
Complex Trichoplax STIL-NTD:human CEP85 coiled coil domain 4
Descriptor: Centrosomal protein of 85 kDa, Putative uncharacterized protein
Authors:van Breugel, M.
Deposit date:2017-07-18
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
5OI9
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BU of 5oi9 by Molmil
Trichoplax adhaerens STIL N-terminal domain
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein
Authors:van Breugel, M.
Deposit date:2017-07-18
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
5OI7
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BU of 5oi7 by Molmil
Human CEP85 - coiled coil domain 4
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal protein of 85 kDa
Authors:van Breugel, M.
Deposit date:2017-07-18
Release date:2018-04-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
7NWJ
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BU of 7nwj by Molmil
Solution NMR structure of the N-terminal domain of CEP164 (1-109)
Descriptor: Centrosomal protein of 164 kDa
Authors:van Breugel, M, Rutherford, T.J.
Deposit date:2021-03-16
Release date:2021-09-15
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
6EWH
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BU of 6ewh by Molmil
Oreochromis niloticus CEP120 second C2 domain (C2B) G307S mutant
Descriptor: Centrosomal protein 120
Authors:van Breugel, M, al-Jassar, C, Yu, M.
Deposit date:2017-11-04
Release date:2018-05-02
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
6EWG
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BU of 6ewg by Molmil
Oreochromis niloticus CEP120 second C2 domain (C2B)
Descriptor: Centrosomal protein 120
Authors:van Breugel, M.
Deposit date:2017-11-04
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
6EWI
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BU of 6ewi by Molmil
Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant
Descriptor: Centrosomal protein 120
Authors:van Breugel, M.
Deposit date:2017-11-04
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
6EWP
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BU of 6ewp by Molmil
Mus musculus CEP120 third C2 domain (C2C)
Descriptor: Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL
Authors:van Breugel, M, al-Jassar, C.
Deposit date:2017-11-06
Release date:2018-05-02
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
6EWL
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BU of 6ewl by Molmil
Danio rerio CEP120 first C2 domain (C2A)
Descriptor: Centrosomal protein 120
Authors:van Breugel, M, al-Jassar, C.
Deposit date:2017-11-04
Release date:2018-05-02
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Cell Rep, 23, 2018
4BXR
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BU of 4bxr by Molmil
Structure of the wild-type TCP10 domain of Danio rerio CPAP in complex with a peptide of Danio rerio STIL
Descriptor: CPAP, SCL-INTERRUPTING LOCUS PROTEIN HOMOLOG
Authors:van Breugel, M.
Deposit date:2013-07-15
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
Elife, 2, 2013
4BXP
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BU of 4bxp by Molmil
Structure of the wild-type TCP10 domain of Danio rerio CPAP
Descriptor: CPAP
Authors:van Breugel, M.
Deposit date:2013-07-15
Release date:2013-09-25
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
Elife, 2, 2013
4BXQ
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BU of 4bxq by Molmil
Structure of the E1021V mutant of the TCP10 domain of Danio rerio CPAP
Descriptor: CPAP
Authors:van Breugel, M.
Deposit date:2013-07-15
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
Elife, 2, 2013
7O06
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BU of 7o06 by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 10Z
Descriptor: Camelid nanobody 10Z, Centrosomal protein of 164 kDa, SULFATE ION
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-03-25
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7O0S
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BU of 7o0s by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 36Z
Descriptor: Centrosomal protein of 164 kDa, Nanobody 36Z
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-03-26
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7O3B
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BU of 7o3b by Molmil
Crystal structure of the TTBK2-CEP164 complex bound to a camelid nanobody
Descriptor: Nanobody 36Z, Tau-tubulin kinase 2,Centrosomal protein of 164 kDa
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-04-01
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
6HXY
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BU of 6hxy by Molmil
Crystal structure of the head and coiled-coil domains of zebrafish CCDC61
Descriptor: Coiled-coil domain-containing protein 61
Authors:Ochi, T, van Breugel, M.
Deposit date:2018-10-18
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020

 

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