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6BWM
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BU of 6bwm by Molmil
Crystal structure of the TRPV2 ion channel
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily V member 2
Authors:Zubcevic, L, Le, S, Yang, H, Lee, S.Y.
Deposit date:2017-12-15
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Conformational plasticity in the selectivity filter of the TRPV2 ion channel.
Nat. Struct. Mol. Biol., 25, 2018
5AN8
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BU of 5an8 by Molmil
Cryo-electron microscopy structure of rabbit TRPV2 ion channel
Descriptor: TRPV2
Authors:Zubcevic, L, Herzik, M.A.J, Chung, B.C, Lander, G.C, Lee, S.Y.
Deposit date:2015-09-04
Release date:2015-12-23
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-Electron Microscopy of the Trpv2 Ion Channel
Nat.Struct.Mol.Biol., 23, 2016
4LP8
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BU of 4lp8 by Molmil
A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Inward rectifier potassium channel Kirbac3.1, ...
Authors:Zubcevic, L, Bavro, V.N, Muniz, J.R.C, Schmidt, M.R, Wang, S, De Zorzi, R, Venien-Bryan, C, Sansom, M.S.P, Nichols, C.G, Tucker, S.J.
Deposit date:2013-07-15
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains.
J.Biol.Chem., 289, 2014
6BWJ
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BU of 6bwj by Molmil
Crystal structure of the TRPV2 ion channel in complex with RTx
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily V member 2, resiniferatoxin
Authors:Zubcevic, L, Le, S, Yang, H, Lee, S.Y.
Deposit date:2017-12-15
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational plasticity in the selectivity filter of the TRPV2 ion channel.
Nat. Struct. Mol. Biol., 25, 2018
6OO3
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BU of 6oo3 by Molmil
Cryo-EM structure of the C4-symmetric TRPV2/RTx complex in amphipol resolved to 2.9 A
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT5
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BU of 6ot5 by Molmil
Structure of the TRPV3 K169A sensitized mutant in the presence of 2-APB at 3.6 A resolution
Descriptor: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6OO4
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BU of 6oo4 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in amphipol resolved to 3.3 A
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT2
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BU of 6ot2 by Molmil
Structure of the TRPV3 K169A sensitized mutant in apo form at 4.1 A resolution
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6MHS
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BU of 6mhs by Molmil
Structure of the human TRPV3 channel in a putative sensitized conformation
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHX
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BU of 6mhx by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHW
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BU of 6mhw by Molmil
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHV
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BU of 6mhv by Molmil
Structure of human TRPV3 in the presence of 2-APB in C4 symmetry
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHO
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BU of 6mho by Molmil
Structure of the human TRPV3 channel in the apo conformation
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6OO7
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BU of 6oo7 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in nanodiscs
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO5
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BU of 6oo5 by Molmil
Cryo-EM structure of the C2-symmetric TRPV2/RTx complex in amphipol resolved to 4.2 A
Descriptor: TRPV2, resiniferatoxin
Authors:Zubcevic, L, Hsu, A.L, Borgnia, M.J, Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
3ZRS
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BU of 3zrs by Molmil
X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at the bundle-crossing gate.
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION
Authors:Bavro, V.N, De Zorzi, R, Schmidt, M.R, Muniz, J.R.C, Zubcevic, L, Sansom, M.S.P, Venien-Bryan, C, Tucker, S.J.
Deposit date:2011-06-17
Release date:2012-01-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
6BPQ
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BU of 6bpq by Molmil
Structure of the cold- and menthol-sensing ion channel TRPM8
Descriptor: Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y, Wu, M, Zubcevic, L, Borschel, W.F, Lander, G.C, Lee, S.-Y.
Deposit date:2017-11-25
Release date:2017-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the cold- and menthol-sensing ion channel TRPM8.
Science, 359, 2018
6PQP
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BU of 6pqp by Molmil
Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist BITC
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-benzylthioformamide, ...
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
6PQQ
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BU of 6pqq by Molmil
Cryo-EM structure of human TRPA1 C621S mutant in the apo state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily A member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
6PQO
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BU of 6pqo by Molmil
Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist JT010
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-N-(3-methoxypropyl)acetamide, ...
Authors:Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y.
Deposit date:2019-07-09
Release date:2020-01-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020

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