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4LP8
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A NOVEL OPEN-STATE CRYSTAL STRUCTURE OF THE PROKARYOTIC INWARD RECTIFIER KIRBAC3.1
Descriptor:Inward rectifier potassium channel Kirbac3.1, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ...
Authors:Zubcevic, L., Bavro, V.N., Muniz, J.R.C., Schmidt, M.R., Wang, S., De Zorzi, R., Venien-Bryan, C., Sansom, M.S.P., Nichols, C.G., Tucker, S.J.
Deposit date:2013-07-15
Release date:2013-11-20
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains.
J.Biol.Chem., 289, 2014
5AN8
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RABBIT TRPV2 ION CHANNEL
Descriptor:TRPV2
Authors:Zubcevic, L., Herzik, M.A.J., Chung, B.C., Lander, G.C., Lee, S.Y.
Deposit date:2015-09-04
Release date:2015-12-23
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-Electron Microscopy of the Trpv2 Ion Channel
Nat.Struct.Mol.Biol., 23, 2016
6BWJ
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CRYSTAL STRUCTURE OF THE TRPV2 ION CHANNEL IN COMPLEX WITH RTX
Descriptor:Transient receptor potential cation channel subfamily V member 2, resiniferatoxin, CALCIUM ION
Authors:Zubcevic, L., Le, S., Yang, H., Lee, S.Y.
Deposit date:2017-12-15
Release date:2018-05-02
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational plasticity in the selectivity filter of the TRPV2 ion channel.
Nat. Struct. Mol. Biol., 25, 2018
6BWM
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CRYSTAL STRUCTURE OF THE TRPV2 ION CHANNEL
Descriptor:Transient receptor potential cation channel subfamily V member 2, CALCIUM ION
Authors:Zubcevic, L., Le, S., Yang, H., Lee, S.Y.
Deposit date:2017-12-15
Release date:2018-05-02
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Conformational plasticity in the selectivity filter of the TRPV2 ion channel.
Nat. Struct. Mol. Biol., 25, 2018
6MHO
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN THE APO CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHS
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN A PUTATIVE SENSITIZED CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHV
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHW
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (1)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6MHX
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (2)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
6OO3
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CRYO-EM STRUCTURE OF THE C4-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 2.9 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO4
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 3.3 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO5
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN AMPHIPOL RESOLVED TO 4.2 A
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OO7
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CRYO-EM STRUCTURE OF THE C2-SYMMETRIC TRPV2/RTX COMPLEX IN NANODISCS
Descriptor:TRPV2, resiniferatoxin
Authors:Zubcevic, L., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-04-22
Release date:2019-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
Elife, 8, 2019
6OT2
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN APO FORM AT 4.1 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
6OT5
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STRUCTURE OF THE TRPV3 K169A SENSITIZED MUTANT IN THE PRESENCE OF 2-APB AT 3.6 A RESOLUTION
Descriptor:Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3, 2-aminoethyl diphenylborinate
Authors:Zubcevic, L., Borschel, W.F., Hsu, A.L., Borgnia, M.J., Lee, S.-Y.
Deposit date:2019-05-02
Release date:2019-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Elife, 8, 2019
3ZRS
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X-RAY CRYSTAL STRUCTURE OF A KIRBAC POTASSIUM CHANNEL HIGHLIGHTS A MECHANISM OF CHANNEL OPENING AT THE BUNDLE-CROSSING GATE.
Descriptor:ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION
Authors:Bavro, V.N., De Zorzi, R., Schmidt, M.R., Muniz, J.R.C., Zubcevic, L., Sansom, M.S.P., Venien-Bryan, C., Tucker, S.J.
Deposit date:2011-06-17
Release date:2012-01-11
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
6BPQ
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STRUCTURE OF THE COLD- AND MENTHOL-SENSING ION CHANNEL TRPM8
Descriptor:Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y., Wu, M., Zubcevic, L., Borschel, W.F., Lander, G.C., Lee, S.-Y.
Deposit date:2017-11-25
Release date:2017-12-13
Last modified:2018-01-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the cold- and menthol-sensing ion channel TRPM8.
Science, 359, 2018