Author results

1E3B
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CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3
分子名称:CYCLOPHILIN 3, GOLD ION, TRIETHYLPHOSPHANE
著者Zou, J., Taylor, P., Dornan, J., Robinson, S.P., Walkinshaw, M.D., Sadler, P.J.
登録日2000-06-08
公開日2000-10-22
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine
Angew.Chem.Int.Ed.Engl., 39, 2000
3G0I
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COMPLEX OF ASPERGILLUS NIGER EPOXIDE HYDROLASE WITH VALPROMIDE (2-PROPYLPENTANAMIDE)
分子名称:Epoxide hydrolase, 2-PROPYLPENTANAMIDE
著者Zou, J., Mowbray, S.L.
登録日2009-01-28
公開日2009-06-09
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage
J.Am.Chem.Soc., 131, 2009
2YGD
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MOLECULAR ARCHITECTURES OF THE 24MERIC EYE LENS CHAPERONE ALPHAB- CRYSTALLIN ELUCIDATED BY A TRIPLE HYBRID APPROACH
分子名称:ALPHA-CRYSTALLIN B CHAIN
著者Braun, N., Zacharias, M., Peschek, J., Kastenmueller, A., Zou, J., Hanzlik, M., Haslbeck, M., Rappsilber, J., Buchner, J., Weinkauf, S.
登録日2011-04-13
公開日2011-12-07
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Multiple Molecular Architectures of the Eye Lens Chaperone Alpha Beta-Crystallin Elucidated by a Triple Hybrid Approach
Proc.Natl.Acad.Sci.USA, 108, 2011
1NU3
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LIMONENE-1,2-EPOXIDE HYDROLASE IN COMPLEX WITH VALPROMIDE
分子名称:limonene-1,2-epoxide hydrolase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-PROPYLPENTANAMIDE
著者Arand, M., Hallberg, B.M., Zou, J., Bergfors, T., Oesch, F., van der Werf, M.J., de Bont, J.A.M., Jones, T.A., Mowbray, S.L.
登録日2003-01-30
公開日2003-06-10
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site
EMBO J., 22, 2003
1NWW
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LIMONENE-1,2-EPOXIDE HYDROLASE
分子名称:Limonene-1,2-epoxide hydrolase, HEPTANAMIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
著者Arand, M., Hallberg, B.M., Zou, J., Bergfors, T., Oesch, F., van der Werf, M.J., de Bont, J.A.M., Jones, T.A., Mowbray, S.L.
登録日2003-02-07
公開日2003-06-10
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site
EMBO J., 22, 2003
4C9Y
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STRUCTURAL BASIS FOR THE MICROTUBULE BINDING OF THE HUMAN KINETOCHORE SKA COMPLEX
分子名称:SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1
著者Abad, M., Medina, B., Santamaria, A., Zou, J., Plasberg-Hill, C., Madhumalar, A., Jayachandran, U., Redli, P.M., Rappsilber, J., Nigg, E.A., Jeyaprakash, A.A.
登録日2013-10-04
公開日2014-01-22
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
4CA0
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STRUCTURAL BASIS FOR THE MICROTUBULE BINDING OF THE HUMAN KINETOCHORE SKA COMPLEX
分子名称:SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1
著者Abad, M., Medina, B., Santamaria, A., Zou, J., Plasberg-Hill, C., Madhumalar, A., Jayachandran, U., Redli, P.M., Rappsilber, J., Nigg, E.A., Jeyaprakash, A.A.
登録日2013-10-04
公開日2014-01-22
実験手法X-RAY DIFFRACTION (2.259 Å)
主引用文献Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
5FBH
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR WITH BOUND GD3+
分子名称:Extracellular calcium-sensing receptor, GADOLINIUM ION, MAGNESIUM ION, ...
著者Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
5FBK
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR
分子名称:Extracellular calcium-sensing receptor, CYCLOMETHYLTRYPTOPHAN, N-ACETYL-D-GLUCOSAMINE, ...
著者Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
1R54
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ADAM33
分子名称:ADAM 33, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Orth, P., Reicher, P., Wang, W., Prosise, W.W., Yarosh-Tomaine, T., Hammond, G., Xiao, L., Mirza, U.A., Zou, J., Strickland, C., Taremi, S.S.
登録日2003-10-09
公開日2004-10-12
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structre of the catalytic domain of human ADAM33
J.Mol.Biol., 335, 2004
1R55
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN ADAM 33
分子名称:ADAM 33, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Orth, P., Reichert, P., Wang, W., Prosise, W.W., Yarosh-Tomaine, T., Hammond, G., Xiao, L., Mirza, U.A., Zou, J., Strickland, C., Taremi, S.S., Le, H.V., Madison, V.
登録日2003-10-09
公開日2004-10-12
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structre of the catalytic domain of human ADAM33
J.Mol.Biol., 335, 2004
3G02
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STRUCTURE OF ENANTIOSELECTIVE MUTANT OF EPOXIDE HYDROLASE FROM ASPERGILLUS NIGER GENERATED BY DIRECTED EVOLUTION
分子名称:Epoxide hydrolase, FORMIC ACID
著者Naworyta, A., Mowbray, S.L.
登録日2009-01-27
公開日2009-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage
J.Am.Chem.Soc., 131, 2009
4BNE
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PACSIN2 INTERACTS WITH MEMBRANES AND ACTIN-FILAMENTS
分子名称:PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2, SULFATE ION, TRIETHYLENE GLYCOL
著者Kostan, J., Salzer, U., Orlova, A., Toeroe, I., Hodnik, V., Schreiner, C., Merilainen, J., Nikki, M., Virtanen, I., Lehto, V.-P., Anderluh, G., Egelman, E.H., Djinovic-Carugo, K.
登録日2013-05-15
公開日2014-05-14
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2.
Embo Rep., 15, 2014
5G2O
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YERSINIA PESTIS FABV VARIANT T276A
分子名称:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
著者Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
登録日2016-04-11
公開日2016-05-25
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
5JAI
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YERSINIA PESTIS FABV VARIANT T276G
分子名称:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, ...
著者Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
登録日2016-04-12
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAM
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YERSINIA PESTIS FABV VARIANT T276V
分子名称:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
著者Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
登録日2016-04-12
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JAQ
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YERSINIA PESTIS FABV VARIANT T276C
分子名称:Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE
著者Pschibul, A., Kuper, J., HIrschbeck, M., Kisker, C.
登録日2016-04-12
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
5JNR
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A
分子名称:Low molecular weight phosphotyrosine protein phosphatase
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNS
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A COMPLEXED WITH PHOSPHATE
分子名称:Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, DIMETHYL SULFOXIDE
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNT
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A COMPLEXED WITH MES
分子名称:Low molecular weight phosphotyrosine protein phosphatase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNU
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CRYSTAL STRUCTURE OF MOUSE LOW-MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE TYPE A (LMPTP-A) COMPLEXED WITH PHOSPHATE
分子名称:Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.535 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNV
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CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) MUTANT (W49Y N50E) COMPLEXED WITH HEPES
分子名称:Low molecular weight phosphotyrosine protein phosphatase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNW
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CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) MUTANT (W49Y N50E) COMPLEXED WITH VANADATE AND UNCOMPETITIVE INHIBITOR
分子名称:Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION, 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5SYB
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CRYSTAL STRUCTURE OF HUMAN PHF5A
分子名称:PHD finger-like domain-containing protein 5A, ZINC ION, 1,2-ETHANEDIOL
著者Tsai, J.H.C., Teng, T., Zhu, P., Fekkes, P., Larsen, N.A.
登録日2016-08-10
公開日2016-09-07
最終更新日2017-06-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Nat Commun, 8, 2017
4BKQ
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ENOYL-ACP REDUCTASE FROM YERSINIA PESTIS (WILDTYPE)WITH COFACTOR NADH
分子名称:PUTATIVE REDUCTASE YPZ3_3519, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
著者Hirschbeck, M.W., Neckles, C., Tonge, P.J., Kisker, C.
登録日2013-04-29
公開日2014-05-14
最終更新日2016-06-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
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