Author results

3KY7
  • Download 3ky7
  • View 3ky7
Molmil generated image of 3ky7
2.35 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PUTATIVE TRNA (GUANINE-7-)-METHYLTRANSFERASE (TRMD) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MRSA252
Descriptor:tRNA (guanine-N(1)-)-methyltransferase
Authors:Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., See, R., Zoraghi, R., Reiner, N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-12-04
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
To be Published
2H40
  • Download 2h40
  • View 2h40
Molmil generated image of 2h40
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF UNLIGANDED PDE5
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION
Authors:Wang, H., Liu, Y., Huai, Q., Cai, J., Zoraghi, R., Francis, S.H., Corbin, J.D., Robinson, H., Xin, Z., Lin, G., Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
3T05
  • Download 3t05
  • View 3t05
Molmil generated image of 3t05
CRYSTAL STRUCTURE OF S. AUREUS PYRUVATE KINASE
Descriptor:Pyruvate kinase, PHOSPHATE ION
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T07
  • Download 3t07
  • View 3t07
Molmil generated image of 3t07
CRYSTAL STRUCTURE OF S. AUREUS PYRUVATE KINASE IN COMPLEX WITH A NATURALLY OCCURRING BIS-INDOLE ALKALOID
Descriptor:Pyruvate kinase, PHOSPHATE ION, (3S,5R)-3,5-bis(6-bromo-1H-indol-3-yl)piperazin-2-one
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T0T
  • Download 3t0t
  • View 3t0t
Molmil generated image of 3t0t
CRYSTAL STRUCTURE OF S. AUREUS PYRUVATE KINASE
Descriptor:Pyruvate kinase, N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION
Authors:Worrall, L.J., Vuckovic, M., Strynadka, N.C.J.
Deposit date:2011-07-20
Release date:2012-06-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol., 7, 2012
2H42
  • Download 2h42
  • View 2h42
Molmil generated image of 2h42
CRYSTAL STRUCTURE OF PDE5 IN COMPLEX WITH SILDENAFIL
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
Authors:Wang, H., Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
2H44
  • Download 2h44
  • View 2h44
Molmil generated image of 2h44
CRYSTAL STRUCTURE OF PDE5A1 IN COMPLEX WITH ICARISID II
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
Authors:Wang, H., Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006