Author results

3P30
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CRYSTAL STRUCTURE OF THE CLUSTER II FAB 1281 IN COMPLEX WITH HIV-1 GP41 ECTODOMAIN
Descriptor:HIV-1 gp41, 1281 Fab light chain, 1281 Fab heavy chain
Authors:Frey, G., Chen, J., Rits-Volloch, S., Freeman, M.M., Zolla-Pazner, S., Chen, B.
Deposit date:2010-10-04
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Nat.Struct.Mol.Biol., 17, 2010
3PIQ
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CRYSTAL STRUCTURE OF HUMAN 2909 FAB, A QUATERNARY STRUCTURE-SPECIFIC ANTIBODY AGAINST HIV-1
Descriptor:Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
Authors:Changela, A., Gorny, M.K., Zolla-Pazner, S., Kwong, P.D.
Deposit date:2010-11-07
Release date:2011-01-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.325 Å)
Cite:Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
1NIZ
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NMR STRUCTURE OF A V3 (MN ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:Exterior membrane glycoprotein(GP120)
Authors:Sharon, M., Kessler, N., Levy, R., Zolla-Pazner, S., Gorlach, M., Anglister, J.
Deposit date:2002-12-30
Release date:2003-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
1NJ0
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NMR STRUCTURE OF A V3 (MN ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:Exterior membrane glycoprotein(GP120)
Authors:Sharon, M., Kessler, N., Levy, R., Zolla-Pazner, S., Gorlach, M., Anglister, J.
Deposit date:2002-12-30
Release date:2003-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
1Q1J
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CRYSTAL STRUCTURE ANALYSIS OF ANTI-HIV-1 FAB 447-52D IN COMPLEX WITH V3 PEPTIDE
Descriptor:Fab 447-52D, light chain, heavy chain, ...
Authors:Stanfield, R.L., Gorny, M.K., Williams, C., Zolla-Pazner, S., Wilson, I.A.
Deposit date:2003-07-21
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.
Structure, 12, 2004
1U6U
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NMR STRUCTURE OF A V3 (IIIB ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:V3 peptide
Authors:Rosen, O., Chill, J., Sharon, M., Kessler, N., Mester, B., Zolla-Pazner, S., Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1U6V
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NMR STRUCTURE OF A V3 (IIIB ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:V3 peptide
Authors:Rosen, O., Chill, J., Sharon, M., Kessler, N., Mester, B., Zolla-Pazner, S., Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
2B0S
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CRYSTAL STRUCTURE ANALYSIS OF ANTI-HIV-1 V3 FAB 2219 IN COMPLEX WITH MN PEPTIDE
Descriptor:Fab 2219, light chain, heavy chain, ...
Authors:Stanfield, R.L., Gorny, M.K., Zolla-Pazner, S., Wilson, I.A.
Deposit date:2005-09-14
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B1A
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CRYSTAL STRUCTURE ANALYSIS OF ANTI-HIV-1 V3 FAB 2219 IN COMPLEX WITH UG1033 PEPTIDE
Descriptor:Fab 2219, light chain, heavy chain, ...
Authors:Stanfield, R.L., Gorny, M.K., Zolla-Pazner, S., Wilson, I.A.
Deposit date:2005-09-15
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B1H
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CRYSTAL STRUCTURE ANALYSIS OF ANTI-HIV-1 V3 FAB 2219 IN COMPLEX WITH UG29 PEPTIDE
Descriptor:Fab 2219, light chain, heavy chain, ...
Authors:Stanfield, R.L., Gorny, M.K., Zolla-Pazner, S., Wilson, I.A.
Deposit date:2005-09-15
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
3Q6F
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CRYSTAL STRUCTURE OF FAB OF HUMAN MAB 2909 SPECIFIC FOR QUATERNARY NEUTRALIZING EPITOPE OF HIV-1 GP120
Descriptor:Light chain of Fab of human mAb 2909, Heavy chain of Fab of human mAb 2909, DI(HYDROXYETHYL)ETHER
Authors:Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.
Deposit date:2010-12-31
Release date:2011-05-25
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
3Q6G
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CRYSTAL STRUCTURE OF FAB OF RHESUS MAB 2.5B SPECIFIC FOR QUATERNARY NEUTRALIZING EPITOPE OF HIV-1 GP120
Descriptor:Light chain of Fab of rhesus mAb 2.5B, Heavy chain of Fab of rhesus mAb 2.5B
Authors:Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.
Deposit date:2010-12-31
Release date:2011-05-25
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
4HPO
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH58 IN COMPLEX WITH V2 PEPTIDE
Descriptor:CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S., Gorman, J., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPY
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH59 IN COMPLEX WITH V2 PEPTIDE
Descriptor:CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S., Gorman, J., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HQQ
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH58
Descriptor:CH58 Fab heavy chain, CH58 Fab light chain
Authors:McLellan, J.S., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-25
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4XMK
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CRYSTAL STRUCTURE OF FAB OF HIV-1 GP120 V3-SPECIFIC HUMAN MONOCLONAL ANTIBODY 2424 IN COMPLEX WITH JR-FL V3 PEPTIDE
Descriptor:Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, HIV-1 JR-FL gp120 V3 peptide
Authors:Kong, X.-P., Pan, R.
Deposit date:2015-01-14
Release date:2015-07-08
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.179 Å)
Cite:Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
J.Virol., 89, 2015
4XML
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CRYSTAL STRUCTURE OF FAB OF HIV-1 GP120 V3-SPECIFIC HUMAN MONOCLONAL ANTIBODY 2424
Descriptor:Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424
Authors:Pan, R., Kong, X.-P.
Deposit date:2015-01-14
Release date:2015-07-08
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
J.Virol., 89, 2015
4ZMJ
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CRYSTAL STRUCTURE OF LIGAND-FREE BG505 SOSIP.664 HIV-1 ENV TRIMER
Descriptor:Envelope glycoprotein gp160, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kwon, Y.D., Kwong, P.D.
Deposit date:2015-05-04
Release date:2015-06-24
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.
Nat.Struct.Mol.Biol., 22, 2015
3C2A
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ANTIBODY FAB FRAGMENT 447-52D IN COMPLEX WITH UG1033 PEPTIDE
Descriptor:Fab 447-52D light chain, Fab 447-52D heavy chain, Envelope glycoprotein
Authors:Dhillon, A.K., Stanfield, R.L., Wilson, I.A.
Deposit date:2008-01-24
Release date:2008-07-08
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set
Acta Crystallogr.,Sect.D, 64, 2008
3GHB
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 447-52D IN COMPLEX WITH V3 PEPTIDE W2RW020
Descriptor:Fab 447-52D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-03
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
3GHE
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 537-10D IN COMPLEX WITH V3 PEPTIDE MN
Descriptor:Fab 537-10D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-03
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
3GO1
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 268-D IN COMPLEX WITH V3 PEPTIDE MN
Descriptor:Fab 268-D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-18
Release date:2010-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLR
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CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 FAB 2557 IN COMPLEX WITH A NY5 V3 PEPTIDE
Descriptor:Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, HIV-1 gp120 third variable region (V3) crown
Authors:Kong, X.-P.
Deposit date:2010-04-18
Release date:2010-07-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLS
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CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 MAB 2557 FAB IN COMPLEX WITH A HIV-1 GP120 V3 MIMOTOPE
Descriptor:Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Rationally designed V3 mimotope
Authors:Kong, X.-P.
Deposit date:2010-04-18
Release date:2010-07-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLT
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CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 FAB 2557 IN COMPLEX WITH A UG1033 V3 PEPTIDE
Descriptor:Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, HIV-1 gp120 third variable region (V3) crown
Authors:Kong, X.-P.
Deposit date:2010-04-18
Release date:2010-07-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
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