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7PWO
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BU of 7pwo by Molmil
Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution
Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ...
Authors:Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
Deposit date:2021-10-07
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
7PWG
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BU of 7pwg by Molmil
Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution
Descriptor: 60S ribosomal protein L13, 60S ribosomal protein L18a, 60S ribosomal protein L27, ...
Authors:Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
Deposit date:2021-10-06
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
7PWF
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BU of 7pwf by Molmil
Cryo-EM structure of small subunit of Giardia lamblia ribosome at 2.9 A resolution
Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ...
Authors:Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
Deposit date:2021-10-06
Release date:2022-05-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
4U67
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BU of 4u67 by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22
Descriptor: 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
Deposit date:2014-07-28
Release date:2015-08-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
6FXC
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BU of 6fxc by Molmil
The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Kidmose, R, Amunts, A, Yonath, A.
Deposit date:2018-03-08
Release date:2018-03-21
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (6.76 Å)
Cite:The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
7A0R
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BU of 7a0r by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2020-08-10
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
7A0S
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BU of 7a0s by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2020-08-10
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
7A18
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BU of 7a18 by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin IV
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2020-08-12
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
4WCE
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BU of 4wce by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
Deposit date:2014-09-04
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.526 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFA
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BU of 4wfa by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.392 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFN
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BU of 4wfn by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
Deposit date:2014-09-16
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
4WF9
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BU of 4wf9 by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with telithromycin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.427 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFB
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BU of 4wfb by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with BC-3205
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
5HL7
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BU of 5hl7 by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eyal, Z, Matzov, D, Krupkin, M, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2016-01-14
Release date:2016-12-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
5HKV
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BU of 5hkv by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23s ribosomal RNA, 50S ribosomal protein L13, ...
Authors:Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M.
Deposit date:2016-01-14
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5JVG
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BU of 5jvg by Molmil
The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ...
Authors:Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
6AZ3
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BU of 6az3 by Molmil
Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin
Descriptor: 60S ribosomal protein L10, putative, 60S ribosomal protein L11 (L5, ...
Authors:Shalev-Benami, M, Zhang, Y, Rozenberg, H, Nobe, Y, Taoka, M, Matzov, D, Zimmerman, E, Bashan, A, Isobe, T, Jaffe, C.L, Yonath, A, Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2022-04-13
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
6AZ1
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BU of 6az1 by Molmil
Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin
Descriptor: E-site tRNA, LACK1, MAGNESIUM ION, ...
Authors:Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
5NGM
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BU of 5ngm by Molmil
2.9S structure of the 70S ribosome composing the S. aureus 100S complex
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Amunts, A, Yonath, A.
Deposit date:2017-03-18
Release date:2017-10-04
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
3M99
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BU of 3m99 by Molmil
Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module
Descriptor: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
Authors:Kohler, A, Zimmerman, E, Schneider, M, Hurt, E, Zheng, N.
Deposit date:2010-03-21
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module.
Cell(Cambridge,Mass.), 141, 2010
6S13
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BU of 6s13 by Molmil
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22).
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6S0Z
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BU of 6s0z by Molmil
Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
5NRG
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BU of 5nrg by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M.
Deposit date:2017-04-23
Release date:2017-08-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.442 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
6S12
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BU of 6s12 by Molmil
Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22).
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
6S0X
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BU of 6s0x by Molmil
Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
Deposit date:2019-06-18
Release date:2019-08-21
Method:ELECTRON MICROSCOPY (2.425 Å)
Cite:Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019

 

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