Author results

1FWP
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CHEY-BINDING DOMAIN OF CHEA (RESIDUES 159-227), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:CHEA
Authors:Mcevoy, M.M., Dahlquist, F.W.
Deposit date:1996-02-06
Release date:1996-07-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and dynamics of a CheY-binding domain of the chemotaxis kinase CheA determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1GMY
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CATHEPSIN B COMPLEXED WITH DIPEPTIDYL NITRILE INHIBITOR
Descriptor:CATHEPSIN B, 2-AMINOETHANIMIDIC ACID, 3-METHYLPHENYLALANINE, ...
Authors:Greenspan, P.D., Clark, K.L., Tommasi, R.A., Cowen, S.D., McQuire, L.W., Farley, D.L., van Duzer, J.H., Goldberg, R.L., Zhou, H., Du, Z., Fitt, J.J., Coppa, D.E., Fang, Z., Macchia, W., Zhu, L., Capparelli, M.P., Goldstein, R., Wigg, A.M., Doughty, J.R., Bohacek, R.S., Knap, A.K.
Deposit date:2001-09-25
Release date:2002-09-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B Through Structure-Based Drug Design
J.Med.Chem., 44, 2001
1K0S
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SOLUTION STRUCTURE OF THE CHEMOTAXIS PROTEIN CHEW FROM THE THERMOPHILIC ORGANISM THERMOTOGA MARITIMA
Descriptor:CHEMOTAXIS PROTEIN CHEW
Authors:Griswold, I.J., Zhou, H., Swanson, R.V., Simon, M.I., Dahlquist, F.W.
Deposit date:2001-09-20
Release date:2002-02-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure and interactions of CheW from Thermotoga maritima.
Nat.Struct.Biol., 9, 2002
1NK1
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NK1 FRAGMENT OF HUMAN HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR (HGF/SF) AT 2.5 ANGSTROM RESOLUTION
Descriptor:PROTEIN (HEPATOCYTE GROWTH FACTOR PRECURSOR)
Authors:Chirgadze, D.Y., Hepple, J.P., Zhou, H., Byrd, R.A., Blundell, T.L., Gherardi, E.
Deposit date:1998-08-20
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.
Nat.Struct.Biol., 6, 1999
1T2M
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SOLUTION STRUCTURE OF THE PDZ DOMAIN OF AF-6
Descriptor:AF-6 protein
Authors:Zhou, H., Wu, J.H., Xu, Y.Q., Huang, A.D., Shi, Y.Y.
Deposit date:2004-04-22
Release date:2005-02-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J.Biol.Chem., 280, 2005
2B23
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HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN AND A GLUCOCORTICOID RECEPTOR-INTERACTING PROTEIN 1 NR BOX II PEPTIDE
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2
Authors:Rajan, S.S., Hsieh, R.W., Sharma, S.K., Greene, G.L.
Deposit date:2005-09-16
Release date:2006-09-19
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2ESW
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ATOMIC STRUCTURE OF THE N-TERMINAL SH3 DOMAIN OF MOUSE BETA PIX,P21-ACTIVATED KINASE (PAK)-INTERACTING EXCHANGE FACTOR
Descriptor:Rho guanine nucleotide exchange factor 7, MERCURY (II) ION, CHLORIDE ION
Authors:Rao, Z.
Deposit date:2005-10-27
Release date:2006-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor
Biochem.Biophys.Res.Commun., 339, 2006
2HGF
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HAIRPIN LOOP CONTAINING DOMAIN OF HEPATOCYTE GROWTH FACTOR, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:HEPATOCYTE GROWTH FACTOR
Authors:Zhou, H., Mazzulla, M.J., Kaufman, J.D., Stahl, S.J., Wingfield, P.T., Rubin, J.S., Bottaro, D.P., Byrd, R.A.
Deposit date:1997-12-18
Release date:1998-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site.
Structure, 6, 1998
2HTJ
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NMR STRUCTURE OF E.COLI PAPI
Descriptor:P fimbrial regulatory protein KS71A
Authors:Kawamura, T., Zhou, H., Le, L.U.K., Dahlquist, F.W.
Deposit date:2006-07-25
Release date:2007-01-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Escherichia coli PapI, a Key Regulator of the Pap Pili Phase Variation.
J.Mol.Biol., 365, 2007
2L4A
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NMR STRUCTURE OF THE DNA-BINDING DOMAIN OF E.COLI LRP
Descriptor:Leucine responsive regulatory protein
Authors:Kawamura, T., Zhou, H., Dahlquist, F.W.
Deposit date:2010-10-01
Release date:2011-03-09
Last modified:2011-08-24
Method:SOLUTION NMR
Cite:The design involved in PapI and Lrp regulation of the pap operon.
J.Mol.Biol., 409, 2011
2LD6
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SOLUTION STRUCTURE OF HISTIDINE PHOSPHOTRANSFER DOMAIN OF CHEA
Descriptor:Chemotaxis protein CheA
Authors:Vu, A., Hamel, D.J., Zhou, H., Dahlquist, F.W.
Deposit date:2011-05-16
Release date:2011-10-12
Method:SOLUTION NMR
Cite:The structure and dynamic properties of the complete histidine phosphotransfer domain of the chemotaxis specific histidine autokinase CheA from Thermotoga maritima.
J.Biomol.Nmr, 51, 2011
2LP4
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SOLUTION STRUCTURE OF P1-CHEY/P2 COMPLEX IN BACTERIAL CHEMOTAXIS
Descriptor:Chemotaxis protein CheA, Chemotaxis protein CheY
Authors:Dahlquist, F., Mo, G., Zhou, H., Kamamura, T.
Deposit date:2012-01-31
Release date:2012-10-24
Method:SOLUTION NMR
Cite:Solution structure of a complex of the histidine autokinase CheA with its substrate CheY.
Biochemistry, 51, 2012
2MC7
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STRUCTURE OF SALMONELLA MGTR
Descriptor:Regulatory peptide
Authors:Jean-Francois, F., Dai, J., Yu, L., Myrick, A., Rubin, E., Fajer, P., Song, L., Zhou, H., Cross, T.
Deposit date:2013-08-15
Release date:2013-10-30
Last modified:2014-01-22
Method:SOLID-STATE NMR
Cite:Binding of MgtR, a Salmonella Transmembrane Regulatory Peptide, to MgtC, a Mycobacterium tuberculosis Virulence Factor: A Structural Study.
J.Mol.Biol., 426, 2014
2MMU
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STRUCTURE OF CRGA, A CELL DIVISION STRUCTURAL AND REGULATORY PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS, IN LIPID BILAYERS
Descriptor:Cell division protein CrgA
Authors:Das, N., Dai, J., Hung, I., Rajagopalan, M., Zhou, H., Cross, T.A.
Deposit date:2014-03-18
Release date:2014-12-17
Last modified:2015-03-25
Method:SOLID-STATE NMR
Cite:Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers.
Proc.Natl.Acad.Sci.USA, 112, 2015
2Q6J
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED TO A B-N SUBSTITUTED LIGAND
Descriptor:Estrogen receptor, GRIP peptide, 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL
Authors:Zhou, H., Nettles, K.W., Bruning, J.B., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K.E., Stossi, F., Katzenellenbogen, B.S., Greene, G.L., Katzenellenbogen, J.A.
Deposit date:2007-06-05
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands
Chem.Biol., 14, 2007
2Q8S
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X-RAY CRYSTAL STRUCTURE OF THE NUCLEAR HORMONE RECEPTOR PPAR-GAMMA IN A COMPLEX WITH A PPAR GAMMA/ALPHA DUAL AGONIST
Descriptor:Peroxisome proliferator-activated receptor gamma, (2S)-3-{4-[3-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)PROPYL]PHENYL}-2-(1H-PYRROL-1-YL)PROPANOIC ACID
Authors:Ohren, J.F.
Deposit date:2007-06-11
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
Bioorg.Med.Chem., 16, 2008
2QA6
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA MUTANT 537S COMPLEXED WITH 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
Descriptor:Estrogen receptor, nuclear receptor coactivator 2, 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-14
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QA8
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN MUTANT 537S COMPLEXED WITH GENISTEIN
Descriptor:Estrogen receptor, nuclear receptor coactivator 2, GENISTEIN
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-14
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QAB
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN MUTANT 537S COMPLEXED WITH AN ETHYL INDAZOLE COMPOUND
Descriptor:Estrogen receptor, nuclear receptor coactivator 2, 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-14
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QFJ
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CRYSTAL STRUCTURE OF FIRST TWO RRM DOMAINS OF FIR BOUND TO SSDNA FROM A PORTION OF FUSE
Descriptor:DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor
Authors:Crichlow, G.V., Yang, Y., Fan, C., Lolis, E., Braddock, D.
Deposit date:2007-06-27
Release date:2008-03-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition
EMBO J., 27, 2007
2QGT
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED TO AN ETHER ESTRADIOL COMPOUND
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-29
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QGW
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH A CHLORO-INDAZOLE COMPOUND
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-29
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QH6
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH AN OXABICYCLIC DIARYLETHYLENE COMPOUND
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
Authors:Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Deposit date:2007-06-29
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QR9
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH AN OXABICYCLIC DERIVATIVE COMPOUND
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
Authors:Nettles, K.W., Bruning, J.B.
Deposit date:2007-07-27
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008
2QSE
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH BURNED MEAT COMPOUND 4-OH-PHIP
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
Authors:Nettles, K.W., Bruning, J.B.
Deposit date:2007-07-30
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4, 2008