Author results

3VMV
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CRYSTAL STRUCTURE OF PECTATE LYASE BSP165PELA FROM BACILLUS SP. N165
Descriptor:Pectate lyase, SULFATE ION
Authors:Zheng, Y., Huang, C.H., Liu, W., Ko, T.P., Xue, Y., Zhou, C., Zhang, G., Guo, R.T., Ma, Y.
Deposit date:2011-12-16
Release date:2012-07-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
3VMW
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CRYSTAL STRUCTURE OF PECTATE LYASE BSP165PELA FROM BACILLUS SP. N165 IN COMPLEX WITH TRIGALACTURONATE
Descriptor:Pectate lyase, ALPHA-D-GALACTOPYRANURONIC ACID, SULFATE ION
Authors:Zheng, Y., Huang, C.H., Liu, W., Ko, T.P., Xue, Y., Zhou, C., Zhang, G., Guo, R.T., Ma, Y.
Deposit date:2011-12-17
Release date:2012-07-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
5AY7
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A PSYCHROPHILIC GLYCOSIDE HYDROLASE FAMILY 10 ENDO-BETA-1,4-XYLANASE
Descriptor:xylanase
Authors:Zheng, Y., Li, Y., Liu, W., Guo, R.T.
Deposit date:2015-08-10
Release date:2016-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase.
J.Struct.Biol., 193, 2016
5D4Y
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A PSYCHROPHILIC GLYCOSIDE HYDROLASE FAMILY 10 ENDO-BETA-1,4-XYLANASE
Descriptor:xylanase, 4-O-beta-D-xylopyranosyl-beta-D-xylopyranose
Authors:Zheng, Y., Guo, R.T.
Deposit date:2015-08-10
Release date:2016-02-24
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase.
J.Struct.Biol., 193, 2016
6OJJ
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STRUCTURE OF SCATG3 WITH TRUNCATIONS IN N-TERMINAL AND FLEXIBLE REGION (FR)
Descriptor:Autophagy-related protein 3,Autophagy-related protein 3, GLYCEROL
Authors:Zheng, Y., Qiu, Y., Schulman, B.A.
Deposit date:2019-04-11
Release date:2019-08-21
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade.
Nat Commun, 10, 2019
3S27
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THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 FROM ARABIDOPSIS THALIANA AND ITS FUNCTIONAL IMPLICATIONS.
Descriptor:Sucrose synthase 1, URIDINE-5'-DIPHOSPHATE, FRUCTOSE, ...
Authors:Zheng, Y., Garavito, R.M.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
3S28
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THE CRYSTAL STRUCTURE OF SUCROSE SYNTHASE-1 IN COMPLEX WITH A BREAKDOWN PRODUCT OF THE UDP-GLUCOSE
Descriptor:Sucrose synthase 1, URIDINE-5'-DIPHOSPHATE, 1,5-anhydro-D-arabino-hex-1-enitol, ...
Authors:Zheng, Y., Garavito, R.M.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
3WGG
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CRYSTAL STRUCTURE OF RSP IN COMPLEX WITH ALPHA-NAD+
Descriptor:Redox-sensing transcriptional repressor rex, alpha-Diphosphopyridine nucleotide, SULFATE ION
Authors:Zheng, Y., Ko, T.-P., Guo, R.-T.
Deposit date:2013-08-05
Release date:2014-08-13
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding mode of the oxidized alpha-anomer of NAD(+) to RSP, a Rex-family repressor
Biochem.Biophys.Res.Commun., 456, 2015
3X2E
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A THERMOPHILIC HYDROLASE
Descriptor:Adenosylhomocysteinase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Zheng, Y., Ko, T.P., Huang, C.H.
Deposit date:2014-12-21
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima
J.Struct.Biol., 2015
3X2F
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A THERMOPHILIC S-ADENOSYLHOMOCYSTEINE HYDROLASE
Descriptor:Adenosylhomocysteinase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SODIUM ION, ...
Authors:Zheng, Y., Ko, T.P., Huang, C.H.
Deposit date:2014-12-21
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima
J.Struct.Biol., 2015
3WG9
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CRYSTAL STRUCTURE OF RSP, A REX-FAMILY REPRESSOR
Descriptor:Redox-sensing transcriptional repressor rex, SULFATE ION
Authors:Zheng, Y., Ko, T.-P., Guo, R.-T.
Deposit date:2013-08-03
Release date:2014-08-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes
J.Struct.Biol., 188, 2014
3WGH
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CRYSTAL STRUCTURE OF RSP IN COMPLEX WITH BETA-NADH
Descriptor:Redox-sensing transcriptional repressor rex, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CACODYLATE ION, ...
Authors:Zheng, Y., Ko, T.-P., Guo, R.-T.
Deposit date:2013-08-05
Release date:2014-08-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes
J.Struct.Biol., 188, 2014
3WGI
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CRYSTAL STRUCTURE OF RSP IN COMPLEX WITH BETA-NAD+ AND OPERATOR DNA
Descriptor:Redox-sensing transcriptional repressor rex, DNA (5'-D(*TP*AP*GP*AP*TP*TP*GP*TP*TP*AP*AP*TP*CP*GP*AP*TP*TP*AP*AP*CP*AP*AP*TP*C)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)
Authors:Zheng, Y., Ko, T.-P., Guo, R.-T.
Deposit date:2013-08-05
Release date:2014-08-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes
J.Struct.Biol., 188, 2014
4YIA
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STRUCTURAL MECHANISM OF HORMONE RELEASE IN THYROXINE BINDING GLOBULIN
Descriptor:Thyroxine-binding globulin, CALCIUM ION, SODIUM ION, ...
Authors:Zheng, Y.
Deposit date:2015-03-01
Release date:2016-03-02
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural mechanism of hormone release in thyroxine Binding globulin
To Be Published
5T1A
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STRUCTURE OF CC CHEMOKINE RECEPTOR 2 WITH ORTHOSTERIC AND ALLOSTERIC ANTAGONISTS
Descriptor:Chimera protein of CC chemokine receptor type 2 isoform B and T4-lysozyme,Lysozyme, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, ...
Authors:Zheng, Y., Qin, L., Ortiz Zacarias, N.V., de Vries, H., Han, G.W., Gustavsson, M., Dabros, M., Zhao, C., Cherney, R.J., Carter, P., Stamos, D., Abagyan, R., Cherezov, V., Stevens, R.C., IJzerman, A.P., Heitman, L.H., Tebben, A., Kufareva, I., Handel, T.M.
Deposit date:2016-08-18
Release date:2016-12-14
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Nature, 540, 2016
5UIW
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CRYSTAL STRUCTURE OF CC CHEMOKINE RECEPTOR 5 (CCR5) IN COMPLEX WITH HIGH POTENCY HIV ENTRY INHIBITOR 5P7-CCL5
Descriptor:C-C chemokine receptor type 5,Rubredoxin chimera, C-C motif chemokine 5, ZINC ION, ...
Authors:Zheng, Y., Qin, L., Han, G.W., Gustavsson, M., Kawamura, T., Stevens, R.C., Cherezov, V., Kufareva, I., Handel, T.M.
Deposit date:2017-01-15
Release date:2017-06-28
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
Immunity, 46, 2017
4ZN9
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH OXABICYCLIC HEPTENE SULFONATE (OBHS)
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, cyclohexa-2,5-dien-1-yl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-04
Release date:2015-09-09
Method:X-RAY DIFFRACTION (2.215 Å)
Cite:Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands.
Chemmedchem, 7, 2012
5MKV
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CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2 (DPYSL2A)/COLLAPSIN RESPONSE MEDIATOR PROTEIN (CRMP2) RESIDUES 13-516
Descriptor:Dihydropyrimidinase-related protein 2, 1,2-ETHANEDIOL
Authors:Sethi, R., Zheng, Y., Krojer, T., Velupillai, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Ahmed, A.A., von Delft, F.
Deposit date:2016-12-05
Release date:2017-02-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5MLE
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CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2 (DPYSL2A)/COLLAPSIN RESPONSE MEDIATOR PROTEIN (CRMP2 13-516) MUTANT Y479E/Y499E
Descriptor:Dihydropyrimidinase-related protein 2, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ...
Authors:Sethi, R., Zheng, Y., Talon, R., Velupillai, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Ahmed, A.A., von Delft, F.
Deposit date:2016-12-06
Release date:2017-02-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
5GO7
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LINEAR TRI-UBIQUITIN
Descriptor:Ubiquitin, D-ubiquitin
Authors:Gao, S., Pan, M., Zheng, Y.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GO8
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LINEAR TETRA-UBIQUITIN
Descriptor:ubiquitin, D-ubiquitin
Authors:Gao, S., Pan, M., Zheng, Y.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOB
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LYS6-LINKED DI-UBIQUITIN
Descriptor:Ubiquitin, D-ubiquitin
Authors:Gao, S., Pan, M., Zheng, Y., Liu, L.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.153 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOC
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LYS11-LINKED DIUBIQUITIN
Descriptor:Ubiquitin, D-ubiquitin, SODIUM ION
Authors:Gao, S., Pan, M., Zheng, Y.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.733 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOD
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LYS27-LINKED DI-UBIQUITIN
Descriptor:Ubiquitin, D-ubiquitin, MAGNESIUM ION
Authors:Gao, S., Pan, M., Zheng, Y.
Deposit date:2016-07-26
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOG
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LYS29-LINKED DI-UBIQUITIN
Descriptor:Ubiquitin, D-ubiquitin
Authors:Gao, S., Pan, M., Zheng, Y.
Deposit date:2016-07-27
Release date:2016-11-02
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.977 Å)
Cite:Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016