Author results

5XSG
  • Download 5xsg
  • View 5xsg
Molmil generated image of 5xsg
ULTRAHIGH RESOLUTION STRUCTURE OF FUS (37-42) SYSGYS DETERMINED BY MICROED
分子名称:RNA-binding protein FUS
著者Luo, F., Gui, X., Zhou, H., Li, D., Li, X., Liu, C.
登録日2017-06-14
公開日2018-04-04
最終更新日2018-04-18
実験手法ELECTRON CRYSTALLOGRAPHY (0.73 Å)
主引用文献Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
5ZGL
  • Download 5zgl
  • View 5zgl
Molmil generated image of 5zgl
HNRNP A1 SEGMENT GGGYGGS (RESIDUES 234-240)
分子名称:7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1
著者Xie, M., Luo, F., Gui, X., Zhao, M., He, J., Li, D., Liu, C.
登録日2018-03-09
公開日2019-04-03
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 as functional ensembles behind stress granule and en route to pathological amyloids
To Be Published
4E0K
  • Download 4e0k
  • View 4e0k
Molmil generated image of 4e0k
CRYSTAL STRUCTURE OF THE AMYLOID-FIBRIL FORMING PEPTIDE KDWSFY DERIVED FROM HUMAN BETA 2 MICROGLOBULIN (58-63)
分子名称:Amyloidogenic peptide segment KDWSFY, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SODIUM ION
著者Zhao, M., Liu, C., Sawaya, M.R., Eisenberg, D.
登録日2012-03-04
公開日2012-12-19
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
1VK1
  • Download 1vk1
  • View 1vk1
Molmil generated image of 1vk1
CONSERVED HYPOTHETICAL PROTEIN FROM PYROCOCCUS FURIOSUS PFU-392566-001
分子名称:Conserved hypothetical protein, PHOSPHATE ION, SODIUM ION, ...
著者Shah, A., Liu, Z.J., Tempel, W., Chen, L., Lee, D., Yang, H., Chang, J., Zhao, M., Ng, J., Rose, J., Brereton, P.S., Izumi, M., Jenney Jr., F.E., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Richardson, D.C., Richardson, J.S., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-04-13
公開日2004-08-10
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献(NZ)CH...O contacts assist crystallization of a ParB-like nuclease.
Bmc Struct.Biol., 7, 2007
3PZZ
  • Download 3pzz
  • View 3pzz
Molmil generated image of 3pzz
STRUCTURE OF AN AMYLOID FORMING PEPTIDE GAIIGL (29-34) FROM AMYLOID BETA
分子名称:Amyloid beta A4 protein
著者Soriaga, A.B., Laganowsky, A.L., Sawaya, M.R., Eisenberg, D.
登録日2010-12-14
公開日2011-10-12
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q27
  • Download 3q27
  • View 3q27
Molmil generated image of 3q27
CYRSTAL STRUCTURE OF HUMAN ALPHA-SYNUCLEIN (32-57) FUSED TO MALTOSE BINDING PROTEIN (MBP)
分子名称:Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, MALTOSE, SULFATE ION, ...
著者Zhao, M., Sawaya, M.R., Cascio, D., Eisenberg, D.
登録日2010-12-19
公開日2011-06-01
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
3FQ9
  • Download 3fq9
  • View 3fq9
Molmil generated image of 3fq9
DESIGN OF AN INSULIN ANALOG WITH ENHANCED RECEPTOR-BINDING SELECTIVITY. RATIONALE, STRUCTURE, AND THERAPEUTIC IMPLICATIONS
分子名称:Insulin, ZINC ION
著者Zhao, M., Wan, Z.L., Whittaker, L., Xu, B., Phillips, N., Katsoyannis, P., Whittaker, J., Weiss, M.A.
登録日2009-01-07
公開日2009-08-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
J.Biol.Chem., 284, 2009
4WY4
  • Download 4wy4
  • View 4wy4
Molmil generated image of 4wy4
CRYSTAL STRUCTURE OF AUTOPHAGIC SNARE COMPLEX
分子名称:Vesicle-associated membrane protein 8, Syntaxin-17, Synaptosomal-associated protein 29
著者Zhao, M., Brunger, A.T.
登録日2014-11-15
公開日2015-02-11
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
5ZGD
  • Download 5zgd
  • View 5zgd
Molmil generated image of 5zgd
HNRNPA1 REVERSIBLE AMYLOID CORE GFGGNDNFG (RESIDUES 209-217) DETERMINED BY X-RAY
分子名称:GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Gui, X., Xie, M., Zhao, M., Luo, F., He, J., Li, D., Liu, C.
登録日2018-03-08
公開日2019-04-03
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 as functional ensembles behind stress granule and en route to pathological amyloids
To Be Published
3SGP
  • Download 3sgp
  • View 3sgp
Molmil generated image of 3sgp
AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100 MUTANT V91L
分子名称:Alpha-crystallin B chain, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL
著者Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
実験手法X-RAY DIFFRACTION (1.4016 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
2HQX
  • Download 2hqx
  • View 2hqx
Molmil generated image of 2hqx
CRYSTAL STRUCTURE OF HUMAN P100 TUDOR DOMAIN CONSERVED REGION
分子名称:P100 CO-ACTIVATOR TUDOR DOMAIN
著者Zhao, M., Liu, Z.J., Xu, H., Yang, J., Silvennoinen, O., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-07-19
公開日2006-10-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystal Structure of Human P100 Tudor Domain Conserved Region
To be Published
3SBB
  • Download 3sbb
  • View 3sbb
Molmil generated image of 3sbb
DISULPHIDE-MEDIATED TETRAMER OF T4 LYSOZYME R76C/R80C BY SYNTHETIC SYMMETRIZATION
分子名称:Lysozyme, CHLORIDE ION
著者Laganowsky, A., Soriaga, A.B., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2015-01-28
実験手法X-RAY DIFFRACTION (1.434 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3Q2X
  • Download 3q2x
  • View 3q2x
Molmil generated image of 3q2x
STRUCTURE OF AN AMYLOID FORMING PEPTIDE NKGAII (RESIDUES 27-32) FROM AMYLOID BETA
分子名称:Amyloid beta A4 protein
著者Soriaga, A.B., Sawaya, M.R., Eisenberg, D.
登録日2010-12-20
公開日2011-10-12
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
5W24
  • Download 5w24
  • View 5w24
Molmil generated image of 5w24
CRYSTAL STRUCTURE OF 5C4 FAB
分子名称:5C4 Fab Light Chain, 5C4 Fab Heavy Chain, (R,R)-2,3-BUTANEDIOL
著者Battles, M.B., McLellan, J.S., Taher, N.M.
登録日2017-06-05
公開日2017-12-06
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
5XRR
  • Download 5xrr
  • View 5xrr
Molmil generated image of 5xrr
CRYSTAL STRUCTURE OF FUS (54-59) SYSSYG
分子名称:RNA-binding protein FUS, ZINC ION
著者Zhao, M., Gui, X., Li, D., Liu, C.
登録日2017-06-09
公開日2018-04-04
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.503 Å)
主引用文献Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
3Q26
  • Download 3q26
  • View 3q26
Molmil generated image of 3q26
CYRSTAL STRUCTURE OF HUMAN ALPHA-SYNUCLEIN (10-42) FUSED TO MALTOSE BINDING PROTEIN (MBP)
分子名称:Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, MALTOSE, GLYCEROL, ...
著者Zhao, M., Sawaya, M.R., Cascio, D., Eisenberg, D.
登録日2010-12-19
公開日2011-06-01
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
3SEW
  • Download 3sew
  • View 3sew
Molmil generated image of 3sew
ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM I)
分子名称:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
著者Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
1YB3
  • Download 1yb3
  • View 1yb3
Molmil generated image of 1yb3
CONSERVED HYPOTHETICAL PROTEIN PFU-178653-001 FROM PYROCOCCUS FURIOSUS
分子名称:hypothetical protein, UNKNOWN ATOM OR ION
著者Habel, J., Zhou, W., Chang, J., Zhao, M., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-19
公開日2005-02-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conserved hypothetical protein Pfu-178653-001 from Pyrococcus furiosus
To be published
2ICU
  • Download 2icu
  • View 2icu
Molmil generated image of 2icu
CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN YEDK FROM ESCHERICHIA COLI
分子名称:Hypothetical protein yedK
著者Chen, L., Liu, Z.J., Li, Y., Zhao, M., Rose, J., Ebihara, A., Yokoyama, S., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-13
公開日2006-11-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Hypothetical Protein YedK From Escherichia coli
To be Published
2IEL
  • Download 2iel
  • View 2iel
Molmil generated image of 2iel
CRYSTAL STRUCTURE OF TT0030 FROM THERMUS THERMOPHILUS
分子名称:Hypothetical Protein TT0030
著者Zhu, J., Huang, J., Stepanyuk, G., Chen, L., Chang, J., Zhao, M., Xu, H., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-09-19
公開日2006-11-14
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
3Q28
  • Download 3q28
  • View 3q28
Molmil generated image of 3q28
CYRSTAL STRUCTURE OF HUMAN ALPHA-SYNUCLEIN (58-79) FUSED TO MALTOSE BINDING PROTEIN (MBP)
分子名称:Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, MALTOSE, SULFATE ION
著者Zhao, M., Sawaya, M.R., Cascio, D., Eisenberg, D.
登録日2010-12-19
公開日2011-06-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
4JHA
  • Download 4jha
  • View 4jha
Molmil generated image of 4jha
CRYSTAL STRUCTURE OF RSV-NEUTRALIZING HUMAN ANTIBODY D25
分子名称:D25 antigen-binding fragment heavy chain, D25 light chain
著者Mclellan, J.S., Chen, M., Leung, S., Graepel, K.W., Du, X., Yang, Y., Zhou, T., Baxa, U., Yasuda, E., Beaumont, T., Kumar, A., Modjarrad, K., Zheng, Z., Zhao, M., Xia, N., Kwong, P.D., Graham, B.S.
登録日2013-03-04
公開日2013-05-01
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
2D59
  • Download 2d59
  • View 2d59
Molmil generated image of 2d59
HYPOTHETICAL PROTEIN FROM PYROCOCCUS HORIKOSHII OT3
分子名称:hypothetical protein PH1109
著者Hiyama, T.B., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-10-31
公開日2006-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of CoA recognition by the Pyrococcus single-domain CoA-binding proteins.
J.STRUCT.FUNCT.GENOM., 7, 2006
4E0N
  • Download 4e0n
  • View 4e0n
Molmil generated image of 4e0n
SVQIVYK SEGMENT FROM HUMAN TAU (305-311) DISPLAYED ON 54-MEMBERED MACROCYCLE SCAFFOLD (FORM II)
分子名称:Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL
著者Zhao, M., Liu, C., Michael, S.R., Eisenberg, D.
登録日2012-03-04
公開日2012-12-19
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
5CCJ
  • Download 5ccj
  • View 5ccj
Molmil generated image of 5ccj
CRYSTAL STRUCTURE OF THE QUINTUPLE MUTANT OF THE SYNAPTOTAGMIN-1 C2B DOMAIN
分子名称:Synaptotagmin-1, GLYCEROL, SULFATE ION
著者Zhou, Q., Zhao, M., Brunger, A.T.
登録日2015-07-02
公開日2015-08-12
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.
Nature, 525, 2015