Author results

4NOJ
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CRYSTAL STRUCTURE OF THE MATURE FORM OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 3.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOK
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN AT PH 7.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOL
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN MUTANT D233A AT PH 7.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOM
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CRYSTAL STRUCTURE OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 4.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
2OST
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THE STRUCTURE OF A BACTERIAL HOMING ENDONUCLEASE : I-SSP6803I
Descriptor:Synthetic DNA 29 MER, Putative endonuclease, CALCIUM ION
Authors:Zhao, L., Bonocora, R.P., Shub, D.A., Stoddard, B.L.
Deposit date:2007-02-06
Release date:2007-03-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The restriction fold turns to the dark side: a bacterial homing endonuclease with a PD-(D/E)-XK motif.
Embo J., 26, 2007
3V6H
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REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES
Descriptor:DNA (5'-D(*TP*CP*AP*CP*(EFG)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*G*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC))-3'), DNA polymerase IV, ...
Authors:Zhao, L.
Deposit date:2011-12-19
Release date:2012-04-25
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Replication of n(2) ,3-ethenoguanine by DNA polymerases.
Angew.Chem.Int.Ed.Engl., 51, 2012
3V6J
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REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES
Descriptor:DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*TP*(EFG)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*C)-3'), ...
Authors:Zhao, L.
Deposit date:2011-12-19
Release date:2012-04-25
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Replication of n(2) ,3-ethenoguanine by DNA polymerases.
Angew.Chem.Int.Ed.Engl., 51, 2012
3V6K
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REPLICATION OF N2,3-ETHENOGUANINE BY DNA POLYMERASES
Descriptor:DNA polymerase IV, DNA (5'-D(P*GP*AP*AP*GP*GP*AP*TP*TP*CP*(2DT))-3'), DNA (5'-D(*TP*CP*AP*CP*(EFG)P*GP*AP*AP*TP*CP*CP*TP*TP*C)-3'), ...
Authors:Zhao, L.
Deposit date:2011-12-20
Release date:2012-04-25
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Replication of n(2) ,3-ethenoguanine by DNA polymerases.
Angew.Chem.Int.Ed.Engl., 51, 2012
4FS1
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BASE PAIRING MECHANISM OF N2,3-ETHENOGUANINE WITH DTTP BY HUMAN POLYMERASE IOTA
Descriptor:DNA 5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3', DNA polymerase iota, MAGNESIUM ION, ...
Authors:Zhao, L.
Deposit date:2012-06-26
Release date:2012-08-29
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases.
J.Biol.Chem., 287, 2012
4FS2
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BASE PAIRING MECHANISM OF N2,3-ETHENOGUANINE WITH DCTP BY HUMAN POLYMERASE IOTA
Descriptor:DNA (5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA polymerase iota, MAGNESIUM ION, ...
Authors:Zhao, L.
Deposit date:2012-06-26
Release date:2012-08-29
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases.
J.Biol.Chem., 287, 2012
5ZC3
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THE CRYSTAL STRUCTURE OF PCRXLR12
Descriptor:RxLR effector
Authors:Zhao, L., Zhang, X., Zhu, C.
Deposit date:2018-02-14
Release date:2018-08-15
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Crystal structure of the RxLR effector PcRxLR12 from Phytophthora capsici
Biochem. Biophys. Res. Commun., 503, 2018
4TQR
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TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO-2'-DEOXYGUANOSINE AND DTTP
Descriptor:DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), DNA (5'-D(*TP*CP*AP*CP*(2LF)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
Authors:Zhao, L.
Deposit date:2014-06-11
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
4TQS
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TERNARY COMPLEX OF Y-FAMILY DNA POLYMERASE DPO4 WITH (5'S)-8,5'-CYCLO-2'-DEOXYGUANOSINE AND DCTP
Descriptor:DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), DNA (5'-D(P*TP*CP*AP*CP*(2LF)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
Authors:Zhao, L.
Deposit date:2014-06-11
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
4UIS
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THE CRYOEM STRUCTURE OF HUMAN GAMMA-SECRETASE COMPLEX
Descriptor:GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L., Zhao, L., Yang, G., Yan, C., Zhou, R., Zhou, X., Xie, T., Zhao, Y., Wu, S., Li, X., Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
5H1B
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HUMAN RAD51 PRESYNAPTIC COMPLEX
Descriptor:DNA repair protein RAD51 homolog 1, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Xu, J., Zhao, L., Xu, Y., Zhao, W., Sung, P., Wang, H.W.
Deposit date:2016-10-08
Release date:2016-12-21
Last modified:2017-10-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Nat. Struct. Mol. Biol., 24, 2017
5H1C
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HUMAN RAD51 POST-SYNAPTIC COMPLEXES
Descriptor:DNA repair protein RAD51 homolog 1, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Xu, J., Zhao, L., Xu, Y., Zhao, W., Sung, P., Wang, H.W.
Deposit date:2016-10-08
Release date:2016-12-21
Last modified:2017-10-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Nat. Struct. Mol. Biol., 24, 2017
6NHW
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 - DIMER OF TRIMER
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Fu, Q., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NHY
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 MUTANT (G217Y) - TRIMER ONLY
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H., Liu, Z.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
2Q0Z
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CRYSTAL STRUCTURE OF Q9P172/SEC63 FROM HOMO SAPIENS. NORTHEAST STRUCTURAL GENOMICS TARGET HR1979.
Descriptor:Protein PRO2281
Authors:Benach, J., Neely, H., Abashidze, M., Edstrom, W.C., Seetharaman, J., Zhao, L., Fang, Y., Cunningham, K., Owens, L., Ma, L.-C., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-05-23
Release date:2007-06-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Q9P172/Sec63 from Homo sapiens.
To be Published
3CEU
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CRYSTAL STRUCTURE OF THIAMINE PHOSPHATE PYROPHOSPHORYLASE (BT_0647) FROM BACTEROIDES THETAIOTAOMICRON. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BTR268
Descriptor:Thiamine phosphate pyrophosphorylase
Authors:Forouhar, F., Chen, Y., Seetharaman, J., Janjua, H., Mao, L., Xiao, R., Foote, E.L., Maglaqui, M., Ciccosanti, C., Zhao, L., Baran, M.C., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-02-29
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of thiamine phosphate pyrophosphorylase (BT_0647) from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR268.
To be Published
3CFU
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CRYSTAL STRUCTURE OF THE YJHA PROTEIN FROM BACILLUS SUBTILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR562
Descriptor:Uncharacterized lipoprotein yjhA
Authors:Vorobiev, S.M., Chen, Y., Kuzin, A.P., Seetharaman, J., Forouhar, F., Zhao, L., Mao, L., Maglaqui, M., Xiao, R., Liu, J., Swapna, G., Huang, J.Y., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-03-04
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the yjhA protein from Bacillus subtilis.
To be Published
3D0W
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CRYSTAL STRUCTURE OF YFLH PROTEIN FROM BACILLUS SUBTILIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR326
Descriptor:YflH protein
Authors:Seetharaman, J., Kuzin, A.P., Neely, H., Forouhar, F., Min, S., Zhao, L., Fang, Y., Owens, L., Ma, L.-C., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-05-02
Release date:2008-05-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of YflH protein from Bacillus subtilis.
To be Published
3D3N
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CRYSTAL STRUCTURE OF LIPASE/ESTERASE (LP_2923) FROM LACTOBACILLUS PLANTARUM. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LPR108
Descriptor:Putative lipase/esterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION
Authors:Forouhar, F., Su, M., Seetharaman, J., Mao, L., Janjua, H., Xiao, R., Ciccosanti, C., Maglaqui, M., Foote, E.L., Zhao, L., Everett, J.K., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-05-12
Release date:2008-06-10
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of lipase/esterase (lp_2923) from Lactobacillus plantarum. Northeast Structural Genomics Consortium target LpR108
To be Published
3DC7
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CRYSTAL STRUCTURE OF THE PROTEIN Q88SR8 FROM LACTOBACILLUS PLANTARUM. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LPR109.
Descriptor:Putative uncharacterized protein lp_3323, SULFATE ION, SODIUM ION, ...
Authors:Kuzin, A.P., Abashidze, M., Vorobiev, S.M., Seetharaman, J., Zhao, L., Mao, L., Ciccosanti, C., Xiao, R., Nair, R., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-06-03
Release date:2008-08-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of the protein Q88SR8 from Lactobacillus plantarum. Northeast Structural Genomics consortium target LpR109. (CASP Target)
To be Published
3DCP
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CRYSTAL STRUCTURE OF THE PUTATIVE HISTIDINOL PHOSPHATASE HISK FROM LISTERIA MONOCYTOGENES. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LMR141.
Descriptor:Histidinol-phosphatase, ZINC ION, FE (III) ION
Authors:Vorobiev, S.M., Su, M., Seetharaman, J., Zhao, L., Mao, L., Foote, E.L., Xiao, R., Nair, R., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-06-04
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the putative histidinol phosphatase hisK from Listeria monocytogenes.
To be Published