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3BCJ
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BU of 3bcj by Molmil
Crystal structure of Aldose Reductase complexed with 2S4R (Stereoisomer of Fidarestat, 2S4S) at 0.78 A
Descriptor: (2S,4R)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose reductase, CITRIC ACID, ...
Authors:Zhao, H.T, El-Kabbani, O.
Deposit date:2007-11-13
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.78 Å)
Cite:Unusual Binding Mode of the 2S4R Stereoisomer of the Potent Aldose Reductase Cyclic Imide Inhibitor Fidarestat (2S4S) in the 15 K Crystal Structure of the Ternary Complex Refined at 0.78 A Resolution: Implications for the Inhibition Mechanism
J.Med.Chem., 51, 2008
3D3W
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BU of 3d3w by Molmil
Structure of L-Xylulose Reductase with bound coenzyme, phosphate and hydroxide.
Descriptor: L-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION
Authors:Zhao, H.-T, El-Kabbani, O.
Deposit date:2008-05-12
Release date:2009-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure/function analysis of a critical disulfide bond in the active site of L-xylulose reductase.
Cell.Mol.Life Sci., 66, 2009

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