Author results

4GGV
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CRYSTAL STRUCTURE OF HMTT INVOLVED IN HIMASTATIN BIOSYNTHESIS
分子名称:Cytochrome P450 superfamily protein, PROTOPORPHYRIN IX CONTAINING FE
著者Zhang, H., Chen, J., Wang, H., Zhang, H.
登録日2012-08-07
公開日2013-07-17
実験手法X-RAY DIFFRACTION (2.331 Å)
主引用文献Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis
Febs Lett., 587, 2013
5XEZ
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
分子名称:Glucagon receptor,Endolysin,Glucagon receptor, Antibody, mAb1, ...
著者Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
登録日2017-04-06
公開日2017-05-24
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5XF1
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
分子名称:Glucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ...
著者Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
登録日2017-04-06
公開日2017-05-24
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5YQZ
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STRUCTURE OF THE GLUCAGON RECEPTOR IN COMPLEX WITH A GLUCAGON ANALOGUE
分子名称:Glucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, N-ACETYL-D-GLUCOSAMINE, ...
著者Zhang, H., Qiao, A., Yang, L., VAN EPS, N., Frederiksen, K., Yang, D., Dai, A., Cai, X., Zhang, H., Yi, C., Can, C., He, L., Yang, H., Lau, J., Ernst, O., Hanson, M., Stevens, R., Wang, M., Seedtz-Runge, S., Jiang, H., Zhao, Q., Wu, B.
登録日2017-11-08
公開日2018-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553, 2018
5GRM
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CRYSTAL STRUCTURE OF RAT STING IN COMPLEX WITH CYCLIC GMP-AMP WITH 2'5'AND 3'5'PHOSPHODIESTER LINKAGE(2'3'-CGAMP)
分子名称:Stimulator of interferon genes protein, cGAMP
著者Zhang, H., Han, M.J., Tao, J.L., Ye, Z.Y., Du, X.X., Deng, M.J., Zhang, X.Y., Li, L.F., Jiang, Z.F., Su, X.D.
登録日2016-08-11
公開日2017-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP)
To Be Published
5GS5
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CRYSTAL STRUCTURE OF APO RAT STING
分子名称:Stimulator of interferon genes protein, SULFATE ION
著者Zhang, H., Han, M.J., Tao, J.L., Ye, Z.Y., Du, X.X., Deng, M.J., Zhang, X.Y., Li, L.F., Jiang, Z.F., Su, X.D.
登録日2016-08-13
公開日2017-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structure of apo ratSTING
To Be Published
4MM0
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CRYSTAL STRUCTURE ANALYSIS OF THE PUTATIVE THIOETHER SYNTHASE SGVP INVOLVED IN THE TAILORING STEP OF GRISEOVIRIDIN
分子名称:P450-like monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Zhang, H., Huang, L., Yi, M., Cai, T., Zhang, H.
登録日2013-09-07
公開日2014-09-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis of SgvP: a Putative Thioether Synthase Involved in the Tailoring Step of Griseoviridin
To be Published
4PV5
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CRYSTAL STRUCTURE OF MOUSE GLYOXALASE I IN COMPLEXED WITH 18-BETA-GLYCYRRHETINIC ACID
分子名称:Lactoylglutathione lyase, ZINC ION, (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID
著者Zhang, H., Zhai, J., Zhang, L.P., Zhao, Y.N., Li, C., Hu, X.P.
登録日2014-03-15
公開日2015-03-18
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for 18-beta-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor
Acta Pharmacol.Sin., 36, 2015
3OFS
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DYNAMIC CONFORMATIONS OF THE CD38-MEDIATED NAD CYCLIZATION CAPTURED USING MULTI-COPY CRYSTALLOGRAPHY
分子名称:ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Zhang, H., Lee, H.C., Hao, Q.
登録日2010-08-16
公開日2010-12-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal
J.Mol.Biol., 405, 2011
4HFF
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CRYSTAL STRUCTURE OF THE TYPE VI EFFECTOR-IMMUNITY COMPLEX TAE4-TAI4 FROM SALMONELLA TYPHIMURIUM
分子名称:Putative cytoplasmic protein, Putative periplasmic protein
著者Zhang, H., Gao, Z.Q., Dong, Y.H.
登録日2012-10-05
公開日2013-01-16
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Structure of the type VI effector-immunity complex (Tae4-Tai4) provides novel insights into the inhibition mechanism of the effector by its immunity protein
J.Biol.Chem., 288, 2013
4HFK
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CRYSTAL STRUCTURE OF THE TYPE VI EFFECTOR-IMMUNITY COMPLEX TAE4-TAI4 FROM ENTEROBACTER CLOACAE
分子名称:Putative cytoplasmic protein, Putative uncharacterized protein, SULFATE ION
著者Zhang, H., Gao, Z.Q., Dong, Y.H.
登録日2012-10-05
公開日2013-01-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the type VI effector-immunity complex (Tae4-Tai4) provides novel insights into the inhibition mechanism of the effector by its immunity protein.
J.Biol.Chem., 288, 2013
4HFL
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CRYSTAL STRUCTURE OF THE TYPE VI EFFECTOR TAE4 FROM ENTEROBACTER CLOACAE
分子名称:Putative cytoplasmic protein
著者Zhang, H., Gao, Z.Q., Dong, Y.H.
登録日2012-10-05
公開日2013-01-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Structure of the type VI effector-immunity complex (Tae4-Tai4) provides novel insights into the inhibition mechanism of the effector by its immunity protein.
J.Biol.Chem., 288, 2013
4X2A
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CRYSTAL STRUCTURE OF MOUSE GLYOXALASE I COMPLEXED WITH BAICALEIN
分子名称:Lactoylglutathione lyase, ZINC ION, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
著者Zhang, H., Zhai, J., Zhang, L., Li, C., Zhao, Y., Hu, X.
登録日2014-11-26
公開日2015-09-16
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献In Vitro Inhibition of Glyoxalase by Flavonoids: New Insights from Crystallographic Analysis
Curr Top Med Chem, 16, 2016
1VQF
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GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 AND ILE 47 REPLACED BY VAL 47 (V35I, I47V)
分子名称:GENE V PROTEIN
著者Zhang, H., Skinner, M.M., Sandberg, W.S., Wang, A.H.-J., Terwilliger, T.C.
登録日1996-08-14
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Context dependence of mutational effects in a protein: the crystal structures of the V35I, I47V and V35I/I47V gene V protein core mutants.
J.Mol.Biol., 259, 1996
1VQI
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GENE V PROTEIN MUTANT WITH ILE 47 REPLACED BY VAL 47 (I47V)
分子名称:GENE V PROTEIN
著者Zhang, H., Skinner, M.M., Sandberg, W.S., Wang, A.H.-J., Terwilliger, T.C.
登録日1996-08-14
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Context dependence of mutational effects in a protein: the crystal structures of the V35I, I47V and V35I/I47V gene V protein core mutants.
J.Mol.Biol., 259, 1996
1VQJ
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GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 (V35I)
分子名称:GENE V PROTEIN
著者Zhang, H., Skinner, M.M., Sandberg, W.S., Wang, A.H.-J., Terwilliger, T.C.
登録日1996-08-14
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Context dependence of mutational effects in a protein: the crystal structures of the V35I, I47V and V35I/I47V gene V protein core mutants.
J.Mol.Biol., 259, 1996
5ZGE
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CRYSTAL STRUCTURE OF NDM-1 AT PH5.5 (BIS-TRIS) IN COMPLEX WITH HYDROLYZED AMPICILLIN
分子名称:Metallo-beta-lactamase type 2, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ZINC ION, ...
著者Zhang, H., Hao, Q.
登録日2018-03-08
公開日2018-08-22
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1.
Antimicrob. Agents Chemother., 62, 2018
1GP7
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ACIDIC PHOSPHOLIPASE A2 FROM VENOM OF OPHIOPHAGUS HANNAH
分子名称:PHOSPHOLIPASE A2, CALCIUM ION
著者Zhang, H., Lin, Z.
登録日2001-10-30
公開日2002-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a Cardiotoxic Phospholipase A(2) from Ophiophagus Hannah with the "Pancreatic Loop"
J.Struct.Biol., 138, 2002
1HS1
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SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAACU AS PART OF HAIRPIN R(GCGUUAACUCGCA)
分子名称:5'-R(*GP*CP*GP*UP*UP*AP*AP*CP*UP*CP*GP*CP*A)-3'
著者Zhang, H., Culyba, M., Volkman, H., Krugh, T.R.
登録日2000-12-22
公開日2003-09-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU)
To be Published
1HS3
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SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAUU AS PART OF HAIRPIN R(GCGUUAAUUCGCA)
分子名称:5'-R(*GP*CP*GP*UP*UP*AP*AP*UP*UP*CP*GP*CP*A)-3'
著者Zhang, H., Culyba, M., Volkman, H., Krugh, T.R.
登録日2000-12-22
公開日2003-09-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU)
To be Published
1HS4
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SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAAU AS PART OF HAIRPIN R(GCGUUAAAUCGCA)
分子名称:5'-R(*GP*CP*GP*UP*UP*AP*AP*AP*UP*CP*GP*CP*A)-3'
著者Zhang, H., Culyba, M., Volkman, H., Krugh, T.R.
登録日2000-12-22
公開日2003-09-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU)
To be Published
3NSP
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CRYSTAL STRUCTURE OF TETRAMERIC RXRALPHA-LBD
分子名称:Retinoid X receptor, alpha
著者Zhang, H., Hu, T., Li, L., Zhou, R., Chen, L., Hu, L., Jiang, H., Shen, X.
登録日2010-07-02
公開日2010-11-17
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
J.Biol.Chem., 286, 2011
3NSQ
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CRYSTAL STRUCTURE OF TETRAMERIC RXRALPHA-LBD COMPLEXED WITH ANTAGONIST DANTHRON
分子名称:Retinoid X receptor, alpha, 1,8-dihydroxyanthracene-9,10-dione
著者Zhang, H., Hu, T., Li, L., Zhou, R., Chen, L., Hu, L., Jiang, H., Shen, X.
登録日2010-07-02
公開日2010-11-17
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
J.Biol.Chem., 286, 2011
3R29
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CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2
分子名称:Retinoic acid receptor RXR-alpha, Nuclear receptor corepressor 2
著者Zhang, H., Chen, L., Chen, J., Jiang, H., Shen, X.
登録日2011-03-14
公開日2011-05-25
最終更新日2011-07-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
3R2A
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CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2 AND ANTAGONIST RHEIN
分子名称:Retinoic acid receptor RXR-alpha, Nuclear receptor corepressor 2, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
著者Zhang, H., Chen, L., Chen, J., Jiang, H., Shen, X.
登録日2011-03-14
公開日2011-05-25
最終更新日2011-07-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011