Author results

4HBG
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CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE 3 OXOACYL-[ACYL CARRIER PROTEIN]-REDUCTASE COMPLEXED WITH NADPH (FORM2)
Descriptor:3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhang, Y.J., Gao, Y.X., Teng, M.K.
Deposit date:2012-09-27
Release date:2013-10-30
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of yeast mitochondria 3-Oxoacyl-ACP Reductase OAR1
To be Published
4K7E
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CRYSTAL STRUCTURE OF JUNIN VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Zhang, Y.J., Li, L., Liu, X., Dong, S.S., Wang, W.M., Huo, T., Rao, Z.H., Yang, C.
Deposit date:2013-04-17
Release date:2013-08-07
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Junin virus nucleoprotein
J.Gen.Virol., 94, 2013
5C2Y
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CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RTR1 (REGULATOR OF TRANSCRIPTION)
Descriptor:RNA polymerase II subunit B1 CTD phosphatase RTR1, ZINC ION, SULFATE ION, ...
Authors:Yogesha, S.D., Irani, S., Zhang, Y.J.
Deposit date:2015-06-16
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
5UIF
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CRYSTAL STRUCTURE OF NATIVE PS01740
Descriptor:Ps01740
Authors:LeVieux, J., Baas, B.J., Zhang, Y.J., Whitman, C.P.
Deposit date:2017-01-13
Release date:2017-11-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily.
Arch. Biochem. Biophys., 636, 2017
5UNQ
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CRYSTAL STRUCTURE OF PT0534 INACTIVATED BY 2-OXO-3-PENTYNOATE
Descriptor:Putative tautomerase
Authors:LeVieux, J., Baas, B.J., Zhang, Y.J., Whitman, C.P.
Deposit date:2017-01-31
Release date:2017-11-22
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.976 Å)
Cite:A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
5V43
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ENGINEERED HUMAN IGG FC DOMAIN AGLYCO801
Descriptor:Ig gamma-1 chain C region
Authors:Yan, W., Marshall, N., Zhang, Y.J.
Deposit date:2017-03-08
Release date:2017-06-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5V4E
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ENGINEERED HUMAN IGG FC DOMAIN GLYCO801 (FC801)
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yan, W., Marshall, N., Zhang, Y.J.
Deposit date:2017-03-09
Release date:2017-06-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.216 Å)
Cite:IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
6BLM
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CRYSTAL STRUCTURE OF NATIVE FUSED 4-OT
Descriptor:4-oxalocrotonate tautomerase
Authors:LeVieux, J., Baas, B.J., Zhang, Y.J., Whitman, C.P.
Deposit date:2017-11-10
Release date:2017-12-06
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.488 Å)
Cite:A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
6DU2
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STRUCTURE OF SCP1 D96N BOUND TO REST-PS861/4 PEPTIDE
Descriptor:carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2, REST-pS861/4, MAGNESIUM ION
Authors:Burkholder, N.T., Mayfield, J.E., Yu, X., Irani, S., Arce, D.K., Jiang, F., Matthews, W., Xue, Y., Zhang, Y.J.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DU3
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STRUCTURE OF SCP1 D96N BOUND TO REST-PS861/4 PEPTIDE
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, REST-pS861, MAGNESIUM ION
Authors:Burkholder, N.T., Mayfield, J.E., Yu, X., Irani, S., Arce, D.K., Jiang, F., Matthews, W., Xue, Y., Zhang, Y.J.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
4YGX
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CRYSTAL STRUCTURE OF D. MELANOGASTER SSU72+SYMPLEKIN BOUND TO CIS PEPTIDOMIMETIC CTD PHOSPHO-SER5 PEPTIDE
Descriptor:Symplekin, LD40846p, cis peptidomimetic CTD phospho-Ser5 peptide
Authors:Mayfield, J.E., Zhang, Y.
Deposit date:2015-02-26
Release date:2015-09-16
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
4YGY
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CRYSTAL STRUCTURE OF HUMAN SCP1 BOUND TO TRANS-PROLINE PEPTIDOMIMETIC CTD PHOSPHO-SER5 PEPTIDE
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, peptidomimetic CTD phospho-Ser5 peptide, MAGNESIUM ION
Authors:Mayfield, J.E., Zhang, Y.
Deposit date:2015-02-26
Release date:2015-09-16
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
4YH1
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STRUCTURE OF HUMAN SCP1 BOUND TO CIS-PROLINE PEPTIDOMIMETIC CTD PHOSPHO-SER5 PEPTIDE
Descriptor:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, A small phosphatase 1, MAGNESIUM ION
Authors:Mayfield, J.E., Zhang, Y.
Deposit date:2015-02-26
Release date:2015-09-16
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
4ZM9
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CRYSTAL STRUCTURE OF CIRCULARLY PERMUTED HUMAN ASPARAGINASE-LIKE PROTEIN 1
Descriptor:Isoaspartyl peptidase/L-asparaginase, SODIUM ION, GLYCINE, ...
Authors:Li, W.Z., Zhang, Y.
Deposit date:2015-05-02
Release date:2016-02-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages.
Biochemistry, 55, 2016
5TIG
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CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BRHPD
Descriptor:2-hydroxymuconate tautomerase, (3E)-5-hydroxy-2-oxopent-3-enoic acid
Authors:Zhang, Y., Li, W., Stack, T.
Deposit date:2016-10-02
Release date:2018-02-21
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
5TSU
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ACTIVE CONFORMATION FOR ENGINEERED HUMAN CYSTATHIONINE GAMMA LYASE (E59N, R119L, E339V) TO DEPLETING METHIONINE
Descriptor:Cystathionine gamma-lyase, METHIONINE, SULFATE ION, ...
Authors:Yan, W., Zhang, Y.
Deposit date:2016-10-31
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Biochemistry, 56, 2017
5TT2
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INACTIVE CONFORMATION OF ENGINEERED HUMAN CYSTATHIONINE GAMMA LYASE (E59N, R119L, E339V) TO DEPLETING METHIONINE
Descriptor:Cystathionine gamma-lyase, SULFATE ION
Authors:Yan, W., Zhang, Y.
Deposit date:2016-10-31
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2.949 Å)
Cite:Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Biochemistry, 56, 2017
5UTS
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CARBON SULFOXIDE LYASE, EGT2 IN THE ERGOTHIONEINE BIOSYNTHESIS PATHWAY
Descriptor:C-S Lyase Egt2, FORMIC ACID
Authors:Irani, S., Zhang, Y.
Deposit date:2017-02-15
Release date:2018-02-21
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Visualization of the C-S lyase sulfenic intermediate in ergothioneine biosynthesis
To Be Published
5V12
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CARBON SULFOXIDE LYASE, EGT2 IN THE ERGOTHIONEINE BIOSYNTHESIS PATHWAY
Descriptor:Hercynylcysteine sulfoxide lyase, FORMIC ACID, (2~{S})-3-(2-oxidanylsulfanyl-1~{H}-imidazol-4-yl)-2-(trimethyl-$l^{4}-azanyl)propanoic acid
Authors:Irani, S., Zhang, Y.
Deposit date:2017-03-01
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Visualization of the C-S lyase sulfenic intermediate in ergothioneine biosynthesis
To Be Published
5V1X
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CARBON SULFOXIDE LYASE, EGT2 Y134F IN COMPLEX WITH ITS SUBSTRATE
Descriptor:Hercynylcysteine sulfoxide lyase, FORMIC ACID, (2~{S})-3-[2-[(2~{R})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]sulfinyl-1~{H}-imidazol-4-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid
Authors:Irani, S., Zhang, Y.
Deposit date:2017-03-02
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.558 Å)
Cite:Visualization of the C-S lyase sulfenic intermediate in ergothioneine biosynthesis
To Be Published
6AKS
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CRYO-EM STRUCTURE OF CVA10 MATURE VIRUS
Descriptor:VP1, VP2, VP3, ...
Authors:Zhu, L., Sun, Y., Fan, J.Y., Zhu, B., Cao, L., Gao, Q., Zhang, Y.J., Liu, H.R., Rao, Z.H., Wang, X.X.
Deposit date:2018-09-03
Release date:2019-01-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
6AKT
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CRYO-EM STRUCTURE OF CVA10 A-PARTICLE
Descriptor:VP1, VP2, VP3
Authors:Zhu, L., Sun, Y., Fan, J.Y., Zhu, B., Cao, L., Gao, Q., Zhang, Y.J., Liu, H.R., Rao, Z.H., Wang, X.X.
Deposit date:2018-09-03
Release date:2019-01-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
6AKU
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CRYO-EM STRUCTURE OF CVA10 EMPTY PARTICLE
Descriptor:VP1, VP2, VP3
Authors:Zhu, L., Sun, Y., Fan, J.Y., Zhu, B., Cao, L., Gao, Q., Zhang, Y.J., Liu, H.R., Rao, Z.H., Wang, X.X.
Deposit date:2018-09-03
Release date:2019-01-16
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
6BGN
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CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE AFTER INCUBATION WITH 5-FLUORO-2-HYDROXY-2,4-PENTADIENOATE
Descriptor:2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ...
Authors:Zhang, Y., Li, W., Stack, T.
Deposit date:2017-10-29
Release date:2018-02-21
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
4N8N
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CRYSTAL STRUCTURE OF MYCOBACTERIAL FTSX EXTRACELLULAR DOMAIN
Descriptor:Cell division protein FtsX, POTASSIUM ION
Authors:Mavrici, D.
Deposit date:2013-10-17
Release date:2014-05-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.
Proc.Natl.Acad.Sci.USA, 111, 2014
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