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5ADY
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
3OMW
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CRYSTAL STRUCTURE OF SSU72, AN ESSENTIAL EUKARYOTIC PHOSPHATASE SPECIFIC FOR THE C-TERMINAL DOMAIN OF RNA POLYMERASE II
Descriptor:CG14216
Authors:Zhang, Y., Zhang, M., Zhang, Y.
Deposit date:2010-08-27
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8701 Å)
Cite:Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
3OMX
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CRYSTAL STRUCTURE OF SSU72 WITH VANADATE COMPLEX
Descriptor:CG14216, VANADATE ION
Authors:Zhang, Y., Zhang, M., Zhang, Y.
Deposit date:2010-08-27
Release date:2011-01-19
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.3366 Å)
Cite:Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
3ZEE
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ELECTRON CYRO-MICROSCOPY HELICAL RECONSTRUCTION OF PAR-3 N TERMINAL DOMAIN
Descriptor:PARTITIONING DEFECTIVE 3 HOMOLOG
Authors:Zhang, Y., Wang, W., Chen, J., Zhang, K., Gao, F., Gong, W., Zhang, M., Sun, F., Feng, W.
Deposit date:2012-12-05
Release date:2013-10-16
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
4KM8
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CRYSTAL STRUCTURE OF SUFUD60
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KM9
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CRYSTAL STRUCTURE OF HUMAN SUPPRESSOR OF FUSED
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KMA
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CRYSTAL STRUCTURE OF DROSOPHILA SUPPRESSOR OF FUSED
Descriptor:GM14141p
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KMD
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CRYSTAL STRUCTURE OF SUFUD60-GLI1P
Descriptor:Sufu, Zinc finger protein GLI1, GLYCEROL, ...
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KMH
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CRYSTAL STRUCTURE OF SUPPRESSOR OF FUSED D20
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
1THD
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COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION
Descriptor:Major envelope protein E
Authors:Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G.
Deposit date:2004-06-01
Release date:2004-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
5E00
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STRUCTURE OF HLA-A2 P130
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, Y., Wu, Y., Qi, J., Liu, J., Gao, G.F., Meng, S.
Deposit date:2015-09-26
Release date:2017-01-18
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
5WSH
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STRUCTURE OF HLA-A2 P130
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, Y., Wu, Y., Qi, J., Liu, J., Gao, G.F., Meng, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
6J1L
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CRYTAL STRUCTURE ANALYSIS OF THE ROR GAMMA(C455E)
Descriptor:Nuclear receptor ROR-gamma, 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide
Authors:zhang, Y., Li, C.C., wu, X.S.
Deposit date:2018-12-28
Release date:2019-05-01
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019
1N6G
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THE STRUCTURE OF IMMATURE DENGUE-2 PRM PARTICLES
Descriptor:major envelope protein E
Authors:Zhang, Y., Corver, J., Chipman, P.R., Zhang, W., Pletnev, S.V., Sedlak, D., Baker, T.S., Strauss, J.H., Kuhn, R.J., Rossmann, M.G.
Deposit date:2002-11-10
Release date:2003-06-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structures of Immature flavivirus particles
EMBO J., 22, 2003
1NA4
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THE STRUCTURE OF IMMATURE YELLOW FEVER VIRUS PARTICLE
Descriptor:major envelope protein E
Authors:Zhang, Y., Corver, J., Chipman, P.R., Lenches, E., Zhang, W., Pletnev, S.V., Sedlak, D., Baker, T.S., Strauss, J.H., Kuhn, R.J., Rossmann, M.G.
Deposit date:2002-11-26
Release date:2003-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Structures of immature flavivirus particles
EMBO J., 22, 2003
1TG8
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THE STRUCTURE OF DENGUE VIRUS E GLYCOPROTEIN
Descriptor:envelope glycoprotein, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Rossmann, M.G.
Deposit date:2004-05-28
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1TGE
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THE STRUCTURE OF IMMATURE DENGUE VIRUS AT 12.5 ANGSTROM
Descriptor:envelope glycoprotein
Authors:Zhang, Y., Zhang, W., Ogata, S., Clements, D., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G.
Deposit date:2004-05-28
Release date:2004-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004
1VZU
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ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, BETA-LACTOSE, ...
Authors:Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K.
Deposit date:2004-05-27
Release date:2004-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
1VZX
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ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K.
Deposit date:2004-05-28
Release date:2004-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
3TKZ
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STRUCTURE OF THE SHP-2 N-SH2 DOMAIN IN A 1:2 COMPLEX WITH RVIPYFVPLNR PEPTIDE
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, PROTEIN (RVIpYFVPLNR peptide)
Authors:Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D.
Deposit date:2011-08-29
Release date:2011-10-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
3TL0
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STRUCTURE OF SHP2 N-SH2 DOMAIN IN COMPLEX WITH RLNPYAQLWHR PEPTIDE
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, RLNpYAQLWHR peptide, SULFATE ION
Authors:Zhang, Y., Zhang, J., Yuan, C., Hard, R.L., Park, I.H., Li, C., Bell, C.E., Pei, D.
Deposit date:2011-08-29
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50, 2011
5BW0
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THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN BINARY COMPLEX OF XCPV AND XCPW FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA
Descriptor:Type II secretion system protein J, Type II secretion system protein I, SULFATE ION
Authors:Zhang, Y., Faucher, F., Poole, K., Jia, Z.
Deposit date:2015-06-05
Release date:2016-07-20
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018
2MNY
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NMR STRUCTURE OF KDM5B PHD1 FINGER
Descriptor:Lysine-specific demethylase 5B, ZINC ION
Authors:Zhang, Y., Yang, H.R., Guo, X., Rong, N.Y., Song, Y.J., Xu, Y.W., Lan, W.X., Xu, Y.H., Cao, C.
Deposit date:2014-04-16
Release date:2014-08-06
Method:SOLUTION NMR
Cite:The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B
Protein Cell, 2014
2MNZ
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NMR STRUCTURE OF KDM5B PHD1 FINGER IN COMPLEX WITH H3K4ME0(1-10AA)
Descriptor:Lysine-specific demethylase 5B, H3K4me0, ZINC ION
Authors:Zhang, Y., Yang, H.R., Guo, X., Rong, N.Y., Song, Y.J., Xu, Y.W., Lan, W.X., Xu, Y.H., Cao, C.
Deposit date:2014-04-16
Release date:2014-08-06
Method:SOLUTION NMR
Cite:The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B
Protein Cell, 2014
5VTM
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THE CRYSTAL STRUCTURE OF MINOR PSEUDOPILIN TERNARY COMPLEX OF XCPVWX FROM THE TYPE 2 SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA
Descriptor:Type II secretion system protein J, Type II secretion system protein K, Type II secretion system protein I, ...
Authors:Zhang, Y., Jia, Z.
Deposit date:2017-05-17
Release date:2018-05-23
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018