Author results

4XNV
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THE HUMAN P2Y1 RECEPTOR IN COMPLEX WITH BPTU
分子名称:P2Y purinoceptor 1, Rubredoxin, 1-[2-(2-tert-butylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]urea, ...
著者Zhang, D., Gao, Z., Jacobson, K., Han, G.W., Stevens, R., Zhao, Q., Wu, B., GPCR Network (GPCR)
登録日2015-01-16
公開日2015-04-01
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two disparate ligand-binding sites in the human P2Y1 receptor
Nature, 520, 2015
4XNW
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THE HUMAN P2Y1 RECEPTOR IN COMPLEX WITH MRS2500
分子名称:P2Y purinoceptor 1,Rubredoxin,P2Y purinoceptor 1, [(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hex-1-yl]methyl dihydrogen phosphate, ZINC ION
著者Zhang, D., Gao, Z., Jacobson, K., Han, G.W., Stevens, R., Zhao, Q., Wu, B., GPCR Network (GPCR)
登録日2015-01-16
公開日2015-04-01
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Two disparate ligand-binding sites in the human P2Y1 receptor
Nature, 520, 2015
2JY5
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NMR STRUCTURE OF UBIQUILIN 1 UBA DOMAIN
分子名称:Ubiquilin-1
著者Zhang, D., Raasi, S., Fushman, D.
登録日2007-12-06
公開日2008-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
2JY6
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SOLUTION STRUCTURE OF THE COMPLEX OF UBIQUITIN AND UBIQUILIN 1 UBA DOMAIN
分子名称:Ubiquitin protein, Ubiquilin-1
著者Zhang, D., Raasi, S., Fushman, D.
登録日2007-12-06
公開日2008-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
1ATL
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STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (FORM-D)
分子名称:ATROLYSIN C, ZINC ION, CALCIUM ION, ...
著者Zhang, D., Botos, I., Gomis-Rueth, F.-X., Doll, R., Blood, C., Njoroge, F.G., Fox, J.W., Bode, W., Meyer, E.F.
登録日1995-05-26
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d).
Proc.Natl.Acad.Sci.USA, 91, 1994
1HTD
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STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (HT-D)
分子名称:ATROLYSIN C, ZINC ION, CALCIUM ION
著者Zhang, D., Botos, I., Gomis-Rueth, F.-X., Doll, R., Blood, C., Njoroge, F.G., Fox, J.W., Bode, W., Meyer, E.F.
登録日1994-01-20
公開日1995-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d).
Proc.Natl.Acad.Sci.USA, 91, 1994
1HYN
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CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN
分子名称:BAND 3 ANION TRANSPORT PROTEIN
著者Zhang, D., Kiyatkin, A., Bolin, J.T., Low, P.S.
登録日2001-01-20
公開日2001-05-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3.
Blood, 96, 2000
3JCD
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STRUCTURE OF ESCHERICHIA COLI EF4 IN POSTTRANSLOCATIONAL RIBOSOMES (POST EF4)
分子名称:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
著者Zhang, D., Yan, K., Liu, G., Song, G., Luo, J., Shi, Y., Cheng, E., Wu, S., Jiang, T., Low, J., Gao, N., Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2018-10-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
3JCE
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STRUCTURE OF ESCHERICHIA COLI EF4 IN PRETRANSLOCATIONAL RIBOSOMES (PRE EF4)
分子名称:16S ribosomal RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
著者Zhang, D., Yan, K., Liu, G., Song, G., Luo, J., Shi, Y., Cheng, E., Wu, S., Jiang, T., Low, J., Gao, N., Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2017-02-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
5ISY
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CRYSTAL STRUCTURE OF NUDIX FAMILY PROTEIN WITH NAD
分子名称:NADH pyrophosphatase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, D., Guan, Z., Zou, T., Yin, P.
登録日2016-03-15
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structural basis of prokaryotic NAD-RNA decapping by NudC
Cell Res., 26, 2016
2MR9
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NMR STRUCTURE OF UBA DOMAIN OF DNA-DAMAGE-INDUCIBLE 1 PROTEIN (DDI1)
分子名称:DNA damage-inducible protein 1
著者Zhang, D., Fushman, D.
登録日2014-07-02
公開日2015-02-04
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
2MRO
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STRUCTURE OF THE COMPLEX OF UBIQUITIN AND THE UBA DOMAIN FROM DNA-DAMAGE-INDUCIBLE 1 PROTEIN (DDI1)
分子名称:Polyubiquitin-B, DNA damage-inducible protein 1
著者Zhang, D., Fushman, D.
登録日2014-07-14
公開日2015-02-04
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
3NS8
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CRYSTAL STRUCTURE OF AN OPEN CONFORMATION OF LYS48-LINKED DIUBIQUITIN AT PH 7.5
分子名称:Ubiquitin, GLYCEROL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Zhang, D., LaRonde-LeBlanc, N., Fushman, D.
登録日2010-07-01
公開日2011-07-20
最終更新日2012-10-17
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
5JMX
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CRYSTAL STRUCTURE OF BCII METALLO-BETA-LACTAMASE IN COMPLEX WITH DZ-305
分子名称:Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ...
著者Stepanovs, D., McDonough, M.A., Schofield, C.J., Zhang, D., Brem, J.
登録日2016-04-29
公開日2017-05-24
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
6EUM
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CRYSTAL STRUCTURE OF BCII METALLO-BETA-LACTAMASE IN COMPLEX WITH DZ-307
分子名称:Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ...
著者Stepanovs, D., McDonough, M.A., Schofield, C.J., Zhang, D., El-Husseiny, A., Brem, J.
登録日2017-10-30
公開日2018-10-03
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
6EWE
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CRYSTAL STRUCTURE OF BCII METALLO-BETA-LACTAMASE IN COMPLEX WITH DZ-308
分子名称:Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ...
著者Stepanovs, D., McDonough, M.A., Schofield, C.J., Zhang, D., El-Husseiny, A., Brem, J.
登録日2017-11-03
公開日2018-10-03
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
6F2N
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CRYSTAL STRUCTURE OF BCII METALLO-BETA-LACTAMASE IN COMPLEX WITH KDU197
分子名称:Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ...
著者McDonough, M.A., El-Hussein, A., Schofield, C.J., Zhang, D., Brem, J.
登録日2017-11-24
公開日2018-10-03
実験手法X-RAY DIFFRACTION (1.149 Å)
主引用文献Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
4U92
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CRYSTAL STRUCTURE OF A DNA/BA2+ G-QUADRUPLEX CONTAINING A WATER-MEDIATED C-TETRAD
分子名称:DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3'), BARIUM ION, MAGNESIUM ION
著者Paukstelis, P.J., Zhang, D., Huang, T., Lukeman, P.
登録日2014-08-05
公開日2014-11-26
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.
Nucleic Acids Res., 42, 2014
5L04
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STRUCTURE OF INTERFERON LAMBDA 1 RECEPTOR WITH HUMAN KINASE JAK1
分子名称:Tyrosine-protein kinase JAK1, Interferon lambda receptor 1
著者Lubkowski, J., Wlodawer, A., Zhang, D.
登録日2016-07-26
公開日2016-10-12
最終更新日2017-04-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of a Complex of the Intracellular Domain of Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1.
J. Mol. Biol., 428, 2016
4M3Q
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE MER IN COMPLEX WITH INHIBITOR UNC1917
分子名称:Tyrosine-protein kinase Mer, CHLORIDE ION, MAGNESIUM ION, ...
著者Zhang, W., Zhang, D., Stashko, M.A., DeRyckere, D., Hunter, D., Kireev, D.B., Miley, M., Cummings, C., Lee, M., Norris-Drouin, J., Stewart, W.M., Sather, S., Zhou, Y., Kirkpatrick, G., Machius, M., Janzen, W.P., Earp, H.S., Graham, D.K., Frye, S., Wang, X.
登録日2013-08-06
公開日2013-11-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.718 Å)
主引用文献Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors.
J.Med.Chem., 56, 2013
4NTJ
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STRUCTURE OF THE HUMAN P2Y12 RECEPTOR IN COMPLEX WITH AN ANTITHROMBOTIC DRUG
分子名称:P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate, CHOLESTEROL, ...
著者Zhang, K., Zhang, J., Gao, Z.-G., Zhang, D., Zhu, L., Han, G.W., Moss, S.M., Paoletta, S., Kiselev, E., Lu, W., Fenalti, G., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
登録日2013-12-02
公開日2014-03-26
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Nature, 509, 2014
4PXZ
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CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESADP
分子名称:P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), ...
著者Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
登録日2014-03-25
公開日2014-04-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
4PY0
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CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESATP
分子名称:P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
著者Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
登録日2014-03-25
公開日2014-04-30
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
5ADY
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX
分子名称:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
著者Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N.
登録日2015-08-25
公開日2015-10-14
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
3P2M
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CRYSTAL STRUCTURE OF A NOVEL ESTERASE RV0045C FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:POSSIBLE HYDROLASE
著者Zheng, X.D., Guo, J., Xu, L., Li, H., Zhang, D., Zhang, K., Sun, F., Wen, T., Liu, S., Pang, H.
登録日2010-10-03
公開日2011-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
Plos One, 6, 2011