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5YZG
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THE CRYO-EM STRUCTURE OF HUMAN CATALYTIC STEP I SPLICEOSOME (C COMPLEX) AT 4.1 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U5 snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhan, X., Yan, C., Zhang, X., Lei, J., Shi, Y.
Deposit date:2017-12-14
Release date:2018-08-08
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of a human catalytic step I spliceosome
Science, 359, 2018
6AH0
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THE CRYO-EM STRUCTURE OF THE PRECUSOR OF HUMAN PRE-CATALYTIC SPLICEOSOME (PRE-B COMPLEX)
Descriptor:U5snRNA, U5 small nuclear ribonucleoprotein 200 kDa helicase, U5 small nuclear ribonucleoprotein 40 kDa protein, ...
Authors:Zhan, X., Yan, C., Zhang, X., Shi, Y.
Deposit date:2018-08-15
Release date:2018-11-14
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6AHD
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THE CRYO-EM STRUCTURE OF HUMAN PRE-CATALYTIC SPLICEOSOME (B COMPLEX) AT 3.8 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U4snRNA, U5snRNA, ...
Authors:Zhan, X., Yan, C., Zhang, X., Shi, Y.
Deposit date:2018-08-17
Release date:2018-11-14
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
3P2D
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CRYSTAL STRUCTURE OF ARRESTIN-3 REVEALS THE BASIS OF THE DIFFERENCE IN RECEPTOR BINDING BETWEEN TWO NON-VISUAL SUBTYPES
Descriptor:Beta-arrestin-2
Authors:Spiller, B.W., Gurevich, V.V., Zhan, X., Gimenez, L.E.
Deposit date:2010-10-01
Release date:2011-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes.
J.Mol.Biol., 406, 2011
5Z56
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CRYO-EM STRUCTURE OF A HUMAN ACTIVATED SPLICEOSOME (MATURE BACT) AT 5.1 ANGSTROM.
Descriptor:Pre-mRNA-processing-splicing factor 8, U5 snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Yan, C., Zhan, X., Li, L., Lei, J., Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z57
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CRYO-EM STRUCTURE OF THE HUMAN ACTIVATED SPLICEOSOME (LATE BACT) AT 6.5 ANGSTROM
Descriptor:Pre-mRNA-processing-splicing factor 8, U5 snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Yan, C., Zhan, X., Li, L., Lei, J., Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z58
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CRYO-EM STRUCTURE OF A HUMAN ACTIVATED SPLICEOSOME (EARLY BACT) AT 4.9 ANGSTROM.
Descriptor:Pre-mRNA-processing-splicing factor 8, U5 snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Yan, C., Zhan, X., Li, L., Lei, J., Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
6ICZ
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CRYO-EM STRUCTURE OF A HUMAN POST-CATALYTIC SPLICEOSOME (P COMPLEX) AT 3.0 ANGSTROM
Descriptor:Protein mago nashi homolog 2, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ID0
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CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME PRIOR TO PRP43 LOADED (ILS1 COMPLEX) AT 2.9 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ID1
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CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME AFTER PRP43 LOADED (ILS2 COMPLEX) AT 2.9 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
5IJB
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THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
1Q5X
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STRUCTURE OF OF RRAA (MENG), A PROTEIN INHIBITOR OF RNA PROCESSING
Descriptor:REGULATOR OF RNASE E ACTIVITY A
Authors:Monzingo, A.F., Gao, J., Qiu, J., Georgiou, G., Robertus, J.D.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003