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1Q5O
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BU of 1q5o by Molmil
HCN2J 443-645 in the presence of cAMP, selenomethionine derivative
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E.
Deposit date:2003-08-08
Release date:2003-09-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:STRUCTURAL BASIS FOR MODULATION AND AGONIST SPECIFICITY OF HCN PACEMAKER CHANNELS
Nature, 425, 2003
1Q43
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BU of 1q43 by Molmil
HCN2I 443-640 in the presence of cAMP, selenomethionine derivative
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E.
Deposit date:2003-08-01
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for modulation and agonist specificity of HCN pacemaker channels
Nature, 425, 2003
1Q3E
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BU of 1q3e by Molmil
HCN2J 443-645 in the presence of cGMP
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E.
Deposit date:2003-07-29
Release date:2003-09-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for modulation and agonist specificity of HCN pacemaker channels
Nature, 425, 2003
5V4S
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BU of 5v4s by Molmil
CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel
Descriptor: Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein
Authors:James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D.
Deposit date:2017-03-10
Release date:2017-04-12
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4EQF
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BU of 4eqf by Molmil
Trip8b-1a#206-567 interacting with the carboxy-terminal seven residues of HCN2
Descriptor: PEX5-related protein, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Bankston, J.R, Camp, S.S, Dimaio, F, Lewis, A.S, Chetkovich, D.M, Zagotta, W.N.
Deposit date:2012-04-18
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Proc.Natl.Acad.Sci.USA, 109, 2012
6AVQ
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BU of 6avq by Molmil
The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V beta-3 Integrin via Steric Hindrance
Descriptor: Integrin alpha-V, Integrin beta-3, LM609 Fab heavy chain, ...
Authors:Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
Deposit date:2017-09-04
Release date:2017-11-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
6AVR
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BU of 6avr by Molmil
Human alpha-V beta-3 Integrin (intermediate conformation) in complex with the therapeutic antibody LM609
Descriptor: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
Authors:Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
Deposit date:2017-09-04
Release date:2017-11-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
6AVU
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BU of 6avu by Molmil
Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609
Descriptor: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
Authors:Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
Deposit date:2017-09-04
Release date:2017-11-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
2PTM
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BU of 2ptm by Molmil
Structure and rearrangements in the carboxy-terminal region of SpIH channels
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT HEXAMMINE(III), Hyperpolarization-activated (Ih) channel
Authors:Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N.
Deposit date:2007-05-08
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure and rearrangements in the carboxy-terminal region of SpIH channels.
Structure, 15, 2007
2Q0A
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BU of 2q0a by Molmil
Structure and rearrangements in the carboxy-terminal region of SpIH channels
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N.
Deposit date:2007-05-21
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and rearrangements in the carboxy-terminal region of SpIH channels.
Structure, 15, 2007
4LLO
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BU of 4llo by Molmil
Structure of the eag domain-CNBHD complex of the mouse EAG1 channel
Descriptor: Potassium voltage-gated channel subfamily H member 1
Authors:Haitin, Y, Carlson, A.E, Zagotta, W.N.
Deposit date:2013-07-09
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:The structural mechanism of KCNH-channel regulation by the eag domain.
Nature, 501, 2013
4OH3
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BU of 4oh3 by Molmil
Crystal structure of a nitrate transporter
Descriptor: DODECYL-BETA-D-MALTOSIDE, NITRATE ION, Nitrate transporter 1.1
Authors:Sun, J, Bankston, J.R, Payandeh, J, Hinds, T.R, Zagotta, W.N, Zheng, N.
Deposit date:2014-01-16
Release date:2014-03-05
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structure of the plant dual-affinity nitrate transporter NRT1.1.
Nature, 507, 2014
3BPZ
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BU of 3bpz by Molmil
HCN2-I 443-460 E502K in the presence of cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Craven, K.B, Olivier, N.B, Zagotta, W.N.
Deposit date:2007-12-19
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:C-terminal movement during gating in cyclic nucleotide-modulated channels.
J.Biol.Chem., 283, 2008
3SWF
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BU of 3swf by Molmil
CNGA1 621-690 containing CLZ domain
Descriptor: ZINC ION, cGMP-gated cation channel alpha-1
Authors:Shuart, N.G, Haitin, Y, Camp, S.S, Black, K.D, Zagotta, W.N.
Deposit date:2011-07-13
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.
Nat Commun, 2, 2011
3SWY
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BU of 3swy by Molmil
CNGA3 626-672 containing CLZ domain
Descriptor: Cyclic nucleotide-gated cation channel alpha-3
Authors:Shuart, N.G, Haitin, Y, Camp, S.S, Black, K.D, Zagotta, W.N.
Deposit date:2011-07-14
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.
Nat Commun, 2, 2011
5OPY
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BU of 5opy by Molmil
Crystal structure of anti-alphaVbeta3 integrin Fab LM609
Descriptor: Heavy chain of LM609 Fab (antigen-binding fragment), Light chain of LM609 Fab (antigen-binding fragment)
Authors:Backovic, M, Veesler, D, Borst, A.J, James, Z.M, Zagotta, W, Ginsberg, M, Rey, F.A, DiMaio, F.
Deposit date:2017-08-10
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
4L11
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BU of 4l11 by Molmil
Structure of the C-linker/CNBHD of agERG channels
Descriptor: AGAP007709-PA
Authors:Brelidze, T.I.
Deposit date:2013-06-01
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the C-terminal region of an ERG channel and functional implications.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ETQ
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BU of 3etq by Molmil
X-ray structure of cysteine-free fragment of mHCN2 C-terminal region from amino acids 443-630 including C508N, C584S, and C601S mutations
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Flynn, G.E.
Deposit date:2008-10-08
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mapping the structure and conformational movements of proteins with transition metal ion FRET.
Nat.Methods, 6, 2009
3FFQ
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BU of 3ffq by Molmil
HCN2I 443-640 apo-state
Descriptor: BROMIDE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Olivier, N.B.
Deposit date:2008-12-04
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mapping the structure and conformational movements of proteins with transition metal ion FRET.
Nat.Methods, 6, 2009
3UKV
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BU of 3ukv by Molmil
Structure of the C-linker/CNBHD of zELK channels in P 1 21 1 space group, crystallized in the presence of cAMP
Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
Authors:Brelidze, T.I.
Deposit date:2011-11-09
Release date:2012-01-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012
3UKN
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BU of 3ukn by Molmil
Structure of the C-linker/CNBHD of zELK channels in C 2 2 21 space group
Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
Authors:Brelidze, T.I.
Deposit date:2011-11-09
Release date:2012-01-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012
3UKT
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BU of 3ukt by Molmil
Structure of the C-linker/CNBHD of zELK channels in P1 21 1 space group
Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
Authors:Brelidze, T.I.
Deposit date:2011-11-09
Release date:2012-01-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012

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