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3L1N
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CRYSTAL STRUCTURE OF MP1P LIGAND BINDING DOMAIN 2 COMPLEXD WITH PALMITIC ACID
Descriptor:Cell wall antigen, PALMITIC ACID
Authors:Liao, S., Tung, E.T., Zheng, W., Chong, K., Xu, Y., Bartlam, M., Rao, Z., Yuen, K.Y.
Deposit date:2009-12-14
Release date:2010-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the Mp1p ligand binding domain 2 reveals its function as a fatty acid-binding protein.
J.Biol.Chem., 285, 2010
5DO2
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COMPLEX STRUCTURE OF MERS-RBD BOUND WITH 4C2 ANTIBODY
Descriptor:S protein, 4C2 heavy chain, 4C2 light chain, ...
Authors:Li, Y., Wan, Y., Liu, P., Zhao, J., Lu, G., Qi, J., Wang, Q., Lu, X., Wu, Y., Liu, W., Yuen, K.Y., Perlman, S., Gao, G.F., Yan, J.
Deposit date:2015-09-10
Release date:2015-10-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.409 Å)
Cite:A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25, 2015
1WOF
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
Deposit date:2004-08-18
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMD
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9
Descriptor:3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-09
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMP
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CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMQ
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CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3
Descriptor:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
Deposit date:2005-08-10
Release date:2005-09-13
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2D2D
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CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR I2
Descriptor:3C-like proteinase, ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE
Authors:Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Ding, Y., Rao, Z.
Deposit date:2005-09-08
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
3SYY
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CRYSTAL STRUCTURE OF AN ALKALINE EXONUCLEASE (LHK-EXO) FROM LARIBACTER HONGKONGENSIS
Descriptor:Exonuclease, MAGNESIUM ION
Authors:Yang, W., Chen, W.Y., Wang, H., Zhang, Q., Zhou, W., Bartlam, M., Watt, R.M., Rao, Z.
Deposit date:2011-07-18
Release date:2012-02-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
3SZ4
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CRYSTAL STRUCTURE OF LHK-EXO IN COMPLEX WITH DAMP
Descriptor:Exonuclease, MAGNESIUM ION, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE
Authors:Yang, W., Chen, W.Y., Wang, H., Zhang, Q., Zhou, W., Bartlam, M., Watt, R.M., Rao, Z.
Deposit date:2011-07-18
Release date:2012-02-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
3SZ5
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CRYSTAL STRUCTURE OF LHK-EXO IN COMPLEX WITH 5-PHOSPHORYLATED OLIGOTHYMIDINE (DT)4
Descriptor:Exonuclease, 5'-D(P*TP*TP*TP*T)-3', MAGNESIUM ION
Authors:Yang, W., Chen, W.Y., Wang, H., Zhang, Q., Zhou, W., Bartlam, M., Watt, R.M., Rao, Z.
Deposit date:2011-07-18
Release date:2012-02-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
4MHH
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CRYSTAL STRUCTURE OF FAB H5M9 IN COMPLEX WITH INFLUENZA VIRUS HEMAGGLUTININ FROM A/VIET NAM/1203/2004 (H5N1)
Descriptor:Hemagglutinin HA1 chain, H5M9 antibody, light chain (kappa), ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (3.564 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4MHI
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CRYSTAL STRUCTURE OF A H5N1 INFLUENZA VIRUS HEMAGGLUTININ FROM A/GOOSE/GUANGDONG/1/96
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4MHJ
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CRYSTAL STRUCTURE OF FAB H5M9 IN COMPLEX WITH INFLUENZA VIRUS HEMAGGLUTININ FROM A/GOOSE/GUANGDONG/1/96 (H5N1)
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, H5M9 antibody, ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (6.98 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4NJL
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CRYSTAL STRUCTURE OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS S2 PROTEIN FUSION CORE
Descriptor:S protein, TRIETHYLENE GLYCOL
Authors:Zhu, Y., Lu, L., Qin, L., Ye, S., Jiang, S., Zhang, R.
Deposit date:2013-11-10
Release date:2014-02-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Nat Commun, 5, 2014
4QZV
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BAT-DERIVED CORONAVIRUS HKU4 USES MERS-COV RECEPTOR HUMAN CD26 FOR CELL ENTRY
Descriptor:Dipeptidyl peptidase 4, Spike protein S1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gao, F.G., Wang, Q.H., Qi, J.X., Lu, G.W.
Deposit date:2014-07-29
Release date:2014-10-29
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26.
Cell Host Microbe, 16, 2014
5CSD
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LIGAND BINDING DOMAIN 2 OF PENICILLIUM MARNEFFEI MP1 PROTEIN IN COMPLEX WITH ARACHIDONIC ACIDS
Descriptor:Envelope glycoprotein, ARACHIDONIC ACID, GLYCEROL
Authors:Lam, W.H., Zhang, H., Hao, Q.
Deposit date:2015-07-23
Release date:2016-07-27
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Cell Chem Biol, 24, 2017
5E7X
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LIGAND BINDING DOMAIN 1 OF PENICILLIUM MARNEFFEI MP1 PROTEIN IN COMPLEX WITH PALMITIC ACID
Descriptor:Cell wall antigen, PALMITIC ACID, ACETATE ION, ...
Authors:Lam, W.H., Zhang, H., Hao, Q.
Deposit date:2015-10-13
Release date:2016-10-19
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Talaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts.
Infect. Immun., 2019
5ECF
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LIGAND BINDING DOMAIN 1 OF PENICILLIUM MARNEFFEI MP1 PROTEIN COMPLEXED WITH ARACHIDONIC ACIDS
Descriptor:Cell wall antigen, ARACHIDONIC ACID
Authors:Lam, W.H., Zhang, H., Hao, Q.
Deposit date:2015-10-20
Release date:2016-10-19
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Talaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts
Infect. Immun., 2019
5FB7
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LIGAND BINDING DOMAIN 2 OF PENICILLIUM MARNEFFEI MP1 PROTEIN COMPLEXED WITH MULTIPLE ARACHIDONIC ACIDS
Descriptor:Envelope glycoprotein, ARACHIDONIC ACID
Authors:Lam, W.H., Zhang, H., Hao, Q.
Deposit date:2015-12-14
Release date:2016-12-14
Last modified:2017-03-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Cell Chem Biol, 24, 2017
5XGR
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STRUCTURE OF THE S1 SUBUNIT C-TERMINAL DOMAIN FROM BAT-DERIVED CORONAVIRUS HKU5 SPIKE PROTEIN
Descriptor:Spike protein S1, N-ACETYL-D-GLUCOSAMINE
Authors:Xue, H., Qi, J., Song, H., Qihui, W., Shi, Y., Gao, G.F.
Deposit date:2017-04-16
Release date:2017-05-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein
Virology, 507, 2017
6J6F
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LIGAND BINDING DOMAIN 1 AND 2 OF TALAROMYCES MARNEFFEI MP1 PROTEIN
Descriptor:Envelope glycoprotein, NICKEL (II) ION
Authors:Lam, W.H., Zhang, H., Hao, Q.
Deposit date:2019-01-15
Release date:2019-03-06
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Talaromyces marneffeiMp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts.
Infect. Immun., 87, 2019