Author results

5X4R
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STRUCTURE OF THE N-TERMINAL DOMAIN (NTD) OF MERS-COV SPIKE PROTEIN
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE
Authors:Yuan, Y., Zhang, Y., Qi, J., Shi, Y., Gao, G.F.
Deposit date:2017-02-14
Release date:2017-05-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X4S
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STRUCTURE OF THE N-TERMINAL DOMAIN (NTD)OF SARS-COV SPIKE PROTEIN
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Yuan, Y., Zhang, Y., Qi, J., Shi, Y., Gao, G.F.
Deposit date:2017-02-14
Release date:2017-05-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X58
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PREFUSION STRUCTURE OF SARS-COV SPIKE GLYCOPROTEIN, CONFORMATION 1
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Yuan, Y., Cao, D., Zhang, Y., Ma, J., Qi, J., Wang, Q., Lu, G., Wu, Y., Yan, J., Shi, Y., Zhang, X., Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X59
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PREFUSION STRUCTURE OF MERS-COV SPIKE GLYCOPROTEIN, THREE-FOLD SYMMETRY
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE
Authors:Yuan, Y., Cao, D., Zhang, Y., Ma, J., Qi, J., Wang, Q., Lu, G., Wu, Y., Yan, J., Shi, Y., Zhang, X., Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5B
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PREFUSION STRUCTURE OF SARS-COV SPIKE GLYCOPROTEIN, CONFORMATION 2
Descriptor:Spike glycoprotein
Authors:Yuan, Y., Cao, D., Zhang, Y., Ma, J., Qi, J., Wang, Q., Lu, G., Wu, Y., Yan, J., Shi, Y., Zhang, X., Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5C
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PREFUSION STRUCTURE OF MERS-COV SPIKE GLYCOPROTEIN, CONFORMATION 1
Descriptor:S protein
Authors:Yuan, Y., Cao, D., Zhang, Y., Ma, J., Qi, J., Wang, Q., Lu, G., Wu, Y., Yan, J., Shi, Y., Zhang, X., Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5F
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PREFUSION STRUCTURE OF MERS-COV SPIKE GLYCOPROTEIN, CONFORMATION 2
Descriptor:S protein
Authors:Yuan, Y., Cao, D., Zhang, Y., Ma, J., Qi, J., Wang, Q., Lu, G., Wu, Y., Yan, J., Shi, Y., Zhang, X., Gao, G.F.
Deposit date:2017-02-15
Release date:2017-05-03
Last modified:2017-05-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
4FMM
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DIMERIC SEC14 FAMILY HOMOLOG 3 FROM SACCHAROMYCES CEREVISIAE PRESENTS SOME NOVEL FEATURES OF STRUCTURE THAT LEAD TO A SURPRISING "DIMER-MONOMER" STATE CHANGE INDUCED BY SUBSTRATE BINDING
Descriptor:Phosphatidylinositol transfer protein PDR16, GLYCEROL, MAGNESIUM ION
Authors:Yuan, Y., Zhao, W., Wang, X., Gao, Y., Niu, L., Teng, M.
Deposit date:2012-06-18
Release date:2013-02-27
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Dimeric Sfh3 has structural changes in its binding pocket that are associated with a dimer-monomer state transformation induced by substrate binding.
Acta Crystallogr.,Sect.D, 69, 2013
2OQO
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CRYSTAL STRUCTURE OF A PEPTIDOGLYCAN GLYCOSYLTRANSFERASE FROM A CLASS A PBP: INSIGHT INTO BACTERIAL CELL WALL SYNTHESIS
Descriptor:Penicillin-binding protein 1A (PBP-1a) (PBP1a), 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE
Authors:Yuan, Y., Sliz, P., Walker, S.
Deposit date:2007-01-31
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1MV5
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CRYSTAL STRUCTURE OF LMRA ATP-BINDING DOMAIN
Descriptor:Multidrug resistance ABC transporter ATP-binding and permease protein, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Yuan, Y., Chen, H., Patel, D.
Deposit date:2002-09-24
Release date:2003-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of LmrA ATP-binding domain reveals the two-site alternating mechanism at molecular level
To be Published
1OSW
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THE STEM OF SL1 RNA IN HIV-1: STRUCTURE AND NUCLEOCAPSID PROTEIN BINDING FOR A 1X3 INTERNAL LOOP
Descriptor:5'-R(*GP*GP*AP*GP*GP*CP*GP*CP*UP*AP*CP*GP*GP*CP*GP*AP*GP*GP*CP*UP*CP*CP*A)-3'
Authors:Yuan, Y., Kerwood, D.J., Paoletti, A.C., Shubsda, M.F., Borer, P.N.
Deposit date:2003-03-20
Release date:2003-05-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Stem of SL1 RNA in HIV-1: Structure and Nucleocapsid Protein Binding for a 1X3 Internal Loop
Biochemistry, 42, 2003
3D3H
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CRYSTAL STRUCTURE OF A COMPLEX OF THE PEPTIDOGLYCAN GLYCOSYLTRANSFERASE DOMAIN FROM AQUIFEX AEOLICUS AND NERYL MOENOMYCIN A
Descriptor:Penicillin-insensitive transglycosylase, (2R)-3-{[(S)-{[(2R,3R,4R,5S,6S)-3-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2R,3R,4S,5R,6S)-6-carbamoyl-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-6-carbamoyl-4-(carbamoyloxy)-5-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]oxy}(hydroxy)phosphoryl]oxy}-2-{[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]oxy}propanoic acid
Authors:Yuan, Y., Sliz, P., Walker, S.
Deposit date:2008-05-11
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.
Acs Chem.Biol., 3, 2008
5V4U
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SOLUTION STRUCTURE OF VKK38 BOUND TO PLASMINOGEN KRINGLE 2
Descriptor:M protein
Authors:Yuan, Y., Castellino, F.
Deposit date:2017-03-10
Release date:2017-07-26
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen.
J. Biol. Chem., 292, 2017
5Z2H
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STRUCTURE OF DICTYOSTELIUM DISCOIDEUM MITOCHONDRIAL CALCIUM UNIPORTER N-TERMINAL DOMAIN(DDMCU-NTD)
Descriptor:Dictyostelium discoideum mitochondrial calcium uniporter
Authors:Yuan, Y., Wen, M., Chou, J.J., Li, D., Bo, O.
Deposit date:2018-01-02
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.674 Å)
Cite:Structural Insights into mitochondrial Calcium Uniporter Regulation by Divalent Cations
To Be Published
5Z2I
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STRUCTURE OF DICTYOSTELIUM DISCOIDEUM MITOCHONDRIAL CALCIUM UNIPORTER N-TERNIMAL DOMAIN (SE-DDMCU-NTD)
Descriptor:Dictyostelium discoideum mitochondrial calcium uniporter
Authors:Yuan, Y., Wen, M., Chou, J., Li, D., Bo, O.
Deposit date:2018-01-02
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structural Insights into mitochondrial Calcium Uniporter Regulation by Divalent Cations
To be Published
5TBG
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin-R1B
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
5TBQ
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
5TBR
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin-R1-B
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
3AWD
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CRYSTAL STRUCTURE OF GOX2181
Descriptor:Putative polyol dehydrogenase, MAGNESIUM ION, CADMIUM ION
Authors:Adam Yuan, Y., Yuan, Z.
Deposit date:2011-03-18
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans.
Biochem.Biophys.Res.Commun., 415, 2011
3NB7
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CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS PEPTIDOGLYCAN GLYCOSYLTRANSFERASE IN COMPLEX WITH DECARBOXYLATED NERYL MOENOMYCIN
Descriptor:Penicillin-binding protein 1A
Authors:Sliz, P., Yuan, Y., Walker, S.
Deposit date:2010-06-02
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.
Acs Chem.Biol., 5, 2010
4EAC
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CRYSTAL STRUCTURE OF MANNONATE DEHYDRATASE FROM ESCHERICHIA COLI STRAIN K12
Descriptor:Mannonate dehydratase, CHLORIDE ION, MANGANESE (II) ION
Authors:Qiu, X., Zhu, Y., Yuan, Y., Zhang, Y., Liu, H., Gao, Y., Teng, M., Niu, L.
Deposit date:2012-03-22
Release date:2013-03-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium.
J.Struct.Biol., 180, 2012
4EAY
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CRYSTAL STRUCTURES OF MANNONATE DEHYDRATASE FROM ESCHERICHIA COLI STRAIN K12 COMPLEXED WITH D-MANNONATE
Descriptor:Mannonate dehydratase, CHLORIDE ION, D-MANNONIC ACID, ...
Authors:Qiu, X., Zhu, Y., Yuan, Y., Zhang, Y., Liu, H., Gao, Y., Teng, M., Niu, L.
Deposit date:2012-03-23
Release date:2013-03-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium.
J.Struct.Biol., 180, 2012
4KQZ
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STRUCTURE OF THE RECEPTOR BINDING DOMAIN (RBD) OF MERS-COV SPIKE
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE
Authors:Lu, G., Hu, Y., Wang, Q., Qi, J., Gao, F., Li, Y., Zhang, Y., Zhang, W., Yuan, Y., Bao, J., Zhang, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-05-15
Release date:2013-07-10
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.514 Å)
Cite:Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
Nature, 500, 2013
4KR0
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COMPLEX STRUCTURE OF MERS-COV SPIKE RBD BOUND TO CD26
Descriptor:Dipeptidyl peptidase 4, S protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lu, G., Hu, Y., Wang, Q., Qi, J., Gao, F., Li, Y., Zhang, Y., Zhang, W., Yuan, Y., Zhang, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-05-15
Release date:2013-07-10
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
Nature, 500, 2013
6BZK
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SOLUTION STRUCTURE OF KTI55
Descriptor:M protein
Authors:Castellino, F.J., Qiu, C., Yuan, Y.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Solution structure of truncated PAM
To Be Published
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