Author results

4JVS
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CRYSTAL STRUCTURE OF LEPB GAP DOMAIN FROM LEGIONELLA DRANCOURTII IN COMPLEX WITH RAB1-GDP AND ALF3
Descriptor:Putative uncharacterized protein, Ras-related protein Rab-1A, ACETIC ACID, ...
Authors:Yu, Q., Yao, Q., Wang, D.-C., Shao, F.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.783 Å)
Cite:Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
5JHE
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THE CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE CO-CHAPERONE CPR7
Descriptor:Peptidyl-prolyl cis-trans isomerase CYP7
Authors:Yu, Q., Xu, L.
Deposit date:2016-04-20
Release date:2017-04-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
To Be Published
6G19
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 74-DEGREE HELICAL TWIST
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-03-20
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1S
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 87-DEGREE HELICAL TWIST
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-03-21
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1X
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 91-DEGREE HELICAL TWIST
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-03-22
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GJZ
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH AMPPNP
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-05-17
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKH
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH ADP-ALF4
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKM
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH ATP (10 MM)
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H61
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 89 DEGREE TWIST AND WITHOUT NUCLEOTIDE
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-07-25
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H66
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 93 DEGREE TWIST AND WITHOUT NUCLEOTIDE
Descriptor:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q., Qu, K., Modis, Y.
Deposit date:2018-07-26
Release date:2018-11-21
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6BHN
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RED LIGHT-ABSORBING STATE OF NPR6012G4, A RED/GREEN CYANOBACTERIOCHROME
Descriptor:Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Yu, Q., Lim, S., Rockwell, N.C., Martin, S.S., Lagarias, J.C., Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3R2W
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CRYSTAL STRUCUTRE OF UDP-GLUCOSE PYROPHOSPHORYLASE OF HOMO SAPIENS
Descriptor:UTP--glucose-1-phosphate uridylyltransferase
Authors:Zheng, X., Yu, Q.
Deposit date:2011-03-14
Release date:2012-02-08
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influences enzymatic activity.
Biochem.J., 442, 2012
6DRF
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STRUCTURE OF HUMAN RETINAL DEGENERATION 3(RD3) PROTEIN
Descriptor:Protein RD3
Authors:Yu, Q., Lim, S., Peshenko, I., Cudia, D., Dizhoor, A.M., Ames, J.B.
Deposit date:2018-06-11
Release date:2019-02-06
Last modified:2019-02-27
Method:SOLUTION NMR
Cite:Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle.
J. Biol. Chem., 294, 2019
6BHO
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GREEN LIGHT-ABSORBING STATE OF NPR6012G4, A RED/GREEN CYANOBACTERIOCHROME
Descriptor:Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Lim, S., Yu, Q., Rockwell, N.C., Martin, S.S., Lagarias, J.C., Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3R3I
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CRYSTAL STRUCTURE OF C-TERMINAL TRUNCATION OF UDP-GLUCOSE PYROPHOSPHORYLASE OF HOMO SAPIENS
Descriptor:UTP--glucose-1-phosphate uridylyltransferase
Authors:Zheng, X., Yu, Q.
Deposit date:2011-03-15
Release date:2012-03-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Crystal Structure of UDP-glucose Pyrophosphorylase of Homo sapiens
To be Published
4DGK
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CRYSTAL STRUCTURE OF PHYTOENE DESATURASE CRTI FROM PANTOEA ANANATIS
Descriptor:Phytoene dehydrogenase, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Schaub, P., Yu, Q., Gemmecker, S., Poussin-Courmontagne, P., Mailliot, J., McEwen, A.G., Ghisla, S., Beyer, P., Cavarelli, J.
Deposit date:2012-01-26
Release date:2012-10-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:On the structure and function of the phytoene desaturase CRTI from Pantoea ananatis, a membrane-peripheral and FAD-dependent oxidase/isomerase.
Plos One, 7, 2012
4EQ8
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CRYSTAL STRUCTURE OF PA1844 FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Putative uncharacterized protein, GLYCEROL
Authors:Shang, G., Li, N., Zhang, J., Lu, D., Yu, Q., Zhao, Y., Liu, X., Xu, S., Gu, L.
Deposit date:2012-04-18
Release date:2012-09-12
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.392 Å)
Cite:Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4EQA
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CRYSTAL STRUCTURE OF PA1844 IN COMPLEX WITH PA1845 FROM PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Putative uncharacterized protein
Authors:Shang, G., Li, N., Zhang, J., Lu, D., Yu, Q., Zhao, Y., Liu, X., Xu, S., Gu, L.
Deposit date:2012-04-18
Release date:2012-09-12
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function.
Biochem.J., 448, 2012
4F5W
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CRYSTAL STRUCTURE OF LIGAND FREE HUMAN STING CTD
Descriptor:Transmembrane protein 173, CALCIUM ION
Authors:Gu, L., Shang, G., Zhu, D., Li, N., Zhang, J., Zhu, C., Lu, D., Liu, C., Yu, Q., Zhao, Y., Xu, S.
Deposit date:2012-05-13
Release date:2012-06-27
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
4F5Y
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CRYSTAL STRUCTURE OF HUMAN STING CTD COMPLEX WITH C-DI-GMP
Descriptor:Transmembrane protein 173, CALCIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Gu, L., Shang, G., Zhu, D., Li, N., Zhang, J., Zhu, C., Lu, D., Liu, C., Yu, Q., Zhao, Y., Xu, S.
Deposit date:2012-05-13
Release date:2012-06-27
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
4UUQ
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CRYSTAL STRUCTURE OF HUMAN MONO-GLYCERIDE LIPASE IN COMPLEX WITH SAR127303
Descriptor:MONOGLYCERIDE LIPASE, 4-({[(4-chlorophenyl)sulfonyl]amino}methyl)piperidine-1-carboxylic acid
Authors:Griebel, G., Pichat, P., Beeske, S., Leroy, T., Redon, N., Francon, D., Bert, L., Even, L., Lopez-Grancha, M., Tolstykh, T., Sun, F., Yu, Q., Brittain, S., Arlt, H., He, T., Zhang, B., Wiederschain, D., Bertrand, T., Houtman, J., Rak, A., Vallee, F., Michot, N., Auge, F., Menet, V., Bergis, O.E., George, P., Avenet, P., Mikol, V., Didier, M., Escoubet, J.
Deposit date:2014-07-30
Release date:2015-01-21
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Selective Blockade of the Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol Impairs Learning and Memory Performance While Producing Antinociceptive Activity in Rodents.
Sci.Rep., 5, 2015
5FX5
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NOVEL INHIBITORS OF HUMAN RHINOVIRUS 3C PROTEASE
Descriptor:RHINOVIRUS 3C PROTEASE, GLYCEROL, TETRAETHYLENE GLYCOL, ...
Authors:Kawatkar, S., Ek, M., Hoesch, V., Gagnon, M., Nilsson, E., Lister, T., Olsson, L., Patel, J., Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
5FX6
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NOVEL INHIBITORS OF HUMAN RHINOVIRUS 3C PROTEASE
Descriptor:RHINOVIRUS 3C PROTEASE, ethyl (4R)-4-[[(2S,4S)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-4-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
Authors:Kawatkar, S., Ek, M., Hoesch, V., Gagnon, M., Nilsson, E., Lister, T., Olsson, L., Patel, J., Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
4JW1
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CRYSTAL STRUCTURE OF N-TERMINAL 618-RESIDUE FRAGMENT OF LEPB FROM LEGIONELLA PNEUMOPHILA
Descriptor:Effector protein B, GLYCEROL, CITRATE ANION
Authors:Hu, L., Yao, Q., Zhu, Y., Shao, F.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
2EXX
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CRYSTAL STRUCTURE OF HSCARG FROM HOMO SAPIENS IN COMPLEX WITH NADP
Descriptor:HSCARG protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL
Authors:Dai, X., Chen, Q., Yao, D., Liang, Y., Dong, Y., Gu, X., Zheng, X., Luo, M.
Deposit date:2005-11-09
Release date:2006-11-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein.
Proc.Natl.Acad.Sci.USA, 104, 2007
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