Author results

6IGO
  • Download 6igo
  • View 6igo
Molmil generated image of 6igo
CRYSTAL STRUCTURE OF MYELIN PROTEIN ZERO-LIKE PROTEIN 1 (MPZL1)
Descriptor:Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-25
Release date:2018-11-28
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
6IGT
  • Download 6igt
  • View 6igt
Molmil generated image of 6igt
MPZL1 MUTANT - V145G, Q146K, P147T AND G148S
Descriptor:Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-26
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
6IGW
  • Download 6igw
  • View 6igw
Molmil generated image of 6igw
MPZL1 MUTANT - S86G, V145G, Q146K,P147T,G148S
Descriptor:Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-26
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
2MLK
  • Download 2mlk
  • View 2mlk
Molmil generated image of 2mlk
THREE-DIMENSIONAL STRUCTURE OF THE C-TERMINAL DNA-BINDING DOMAIN OF RSTA PROTEIN FROM KLEBSIELLA PNEUMONIAE
Descriptor:RstA
Authors:Fang, P., Chen, S., Cheng, Y., Chang, C., Yu, T., Huang, T.
Deposit date:2014-03-02
Release date:2014-07-16
Last modified:2014-08-13
Method:SOLUTION NMR
Cite:Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
4Y3I
  • Download 4y3i
  • View 4y3i
Molmil generated image of 4y3i
PAS-GAF FRAGMENT FROM DEINOCOCCUS RADIODURANS BPHP ASSEMBLED WITH BV - Y307S, LOW DOSE
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Li, F., Burgie, E.S., Yu, T., Heroux, A., Schatz, G.C., Vierstra, R.D., Orville, A.M.
Deposit date:2015-02-10
Release date:2015-05-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
4Y5F
  • Download 4y5f
  • View 4y5f
Molmil generated image of 4y5f
PAS-GAF FRAGMENT FROM DEINOCOCCUS RADIODURANS BPHP ASSEMBLED WITH BV - Y307S, HIGH DOSE
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Li, F., Burgie, E.S., Yu, T., Heroux, A., Schatz, G.C., Vierstra, R.D., Orville, A.M.
Deposit date:2015-02-11
Release date:2015-05-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
6INE
  • Download 6ine
  • View 6ine
Molmil generated image of 6ine
CRYSTAL STRUCTURE OF HUMAN ASH1L-MRG15 COMPLEX
Descriptor:Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ZINC ION, ...
Authors:Hou, P., Huang, C., Liu, C.P., Yu, T., Yin, Y., Zhu, B., Xu, R.M.
Deposit date:2018-10-25
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 2019
4CWM
  • Download 4cwm
  • View 4cwm
Molmil generated image of 4cwm
HIGH-GLYCOSYLATION CRYSTAL STRUCTURE OF THE BIFUNCTIONAL ENDONUCLEASE (ATBFN2) FROM ARABIDOPSIS THALIANA
Descriptor:ENDONUCLEASE 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yu, T.-F., Maestre-Reyna, M., Ko, C.-Y., Ko, T.-P., Sun, Y.-J., Lin, T.-Y., Shaw, J.-F., Wang, A.H.-J.
Deposit date:2014-04-03
Release date:2014-07-23
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana.
Plos One, 9, 2014
4CXO
  • Download 4cxo
  • View 4cxo
Molmil generated image of 4cxo
BIFUNCTIONAL ENDONUCLEASE IN COMPLEX WITH SSDNA
Descriptor:ENDONUCLEASE 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yu, T.-F., Maestre-Reyna, M., Ko, C.-Y., Ko, T.-P., Sun, Y.-J., Lin, T.-Y., Shaw, J.-F., Wang, A.H.-J.
Deposit date:2014-04-08
Release date:2014-07-23
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana.
Plos One, 9, 2014
4CXP
  • Download 4cxp
  • View 4cxp
Molmil generated image of 4cxp
STRUCTURE OF BIFUNCTIONAL ENDONUCLEASE (ATBFN2) FROM ARABIDOPSIS THALIANA IN COMPLEX WITH SULFATE
Descriptor:ENDONUCLEASE 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yu, T.-F., Maestre-Reyna, M., Ko, C.-Y., Ko, T.-P., Sun, Y.-J., Lin, T.-Y., Shaw, J.-F., Wang, A.H.-J.
Deposit date:2014-04-08
Release date:2014-07-23
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana.
Plos One, 9, 2014
4CXV
  • Download 4cxv
  • View 4cxv
Molmil generated image of 4cxv
STRUCTURE OF BIFUNCTIONAL ENDONUCLEASE (ATBFN2) IN COMPLEX WITH PHOSPHATE.
Descriptor:ENDONUCLEASE 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yu, T.-F., Maestre-Reyna, M., Ko, C.-Y., Ko, T.-P., Sun, Y.-J., Lin, T.-Y., Shaw, J.-F., Wang, A.H.-J.
Deposit date:2014-04-09
Release date:2014-07-23
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights of the Ssdna Binding Site in the Multifunctional Endonuclease Atbfn2 from Arabidopsis Thaliana.
Plos One, 9, 2014
3MYG
  • Download 3myg
  • View 3myg
Molmil generated image of 3myg
AURORA A KINASE COMPLEXED WITH SCH 1473759
Descriptor:Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL, 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol
Authors:Hruza, A., Prosis, W., Ramanathan, L.
Deposit date:2010-05-10
Release date:2010-07-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.
ACS Med Chem Lett, 1, 2010
2MNU
  • Download 2mnu
  • View 2mnu
Molmil generated image of 2mnu
BACKBONE AND SIDE CHAIN 1H, 13C, AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR EDB AND SPECIFIC BINDING APTIDE
Descriptor:EDB, APT
Authors:Suh, J., Yu, T.
Deposit date:2014-04-10
Release date:2014-09-24
Method:SOLUTION NMR
Cite:An Unusual Protein-Protein Interaction through Coupled Unfolding and Binding
Angew.Chem.Int.Ed.Engl., 53, 2014
2VH7
  • Download 2vh7
  • View 2vh7
Molmil generated image of 2vh7
CRYSTAL STRUCTURE OF HUMAN COMMON-TYPE ACYLPHOSPHATASE
Descriptor:ACYLPHOSPHATASE-1
Authors:Yeung, R.C.Y., Lam, Y., Wong, K.B.
Deposit date:2007-11-19
Release date:2009-03-17
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
2W4C
  • Download 2w4c
  • View 2w4c
Molmil generated image of 2w4c
HUMAN COMMON-TYPE ACYLPHOSPHATASE VARIANT, A99
Descriptor:ACYLPHOSPHATASE-1
Authors:Lam, S.Y., Wong, K.B.
Deposit date:2008-11-25
Release date:2009-12-22
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
2W4D
  • Download 2w4d
  • View 2w4d
Molmil generated image of 2w4d
ACYLPHOSPHATASE VARIANT G91A FROM PYROCOCCUS HORIKOSHII
Descriptor:ACYLPHOSPHATASE, POTASSIUM ION, PHOSPHATE ION
Authors:Lam, S.Y., Wong, K.B.
Deposit date:2008-11-25
Release date:2009-12-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
2W4P
  • Download 2w4p
  • View 2w4p
Molmil generated image of 2w4p
HUMAN COMMON-TYPE ACYLPHOSPHATASE VARIANT, A99G
Descriptor:ACYLPHOSPHATASE-1, GLYCEROL
Authors:Lam, S.Y., Sze, K.H., Wong, K.B.
Deposit date:2008-11-29
Release date:2009-12-29
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity.
Plos Biol., 9, 2011
3H42
  • Download 3h42
  • View 3h42
Molmil generated image of 3h42
CRYSTAL STRUCTURE OF PCSK9 IN COMPLEX WITH FAB FROM LDLR COMPETITIVE ANTIBODY
Descriptor:Proprotein convertase subtilisin/kexin type 9, Fab from LDLR competitive antibody: Light chain, Fab from LDLR competitive antibody: Heavy chain, ...
Authors:Piper, D.E., Walker, N.P.C., Romanow, W.G., Thibault, S.T., Tsai, M.M., Yang, E.
Deposit date:2009-04-17
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
3O7L
  • Download 3o7l
  • View 3o7l
Molmil generated image of 3o7l
CRYSTAL STRUCTURE OF PHOSPHOLAMBAN (1-19):PKA C-SUBUNIT:AMP-PNP:MG2+ COMPLEX
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, Cardiac phospholamban, MAGNESIUM ION, ...
Authors:Cheng, C.Y., Taylor, S.S.
Deposit date:2010-07-30
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dynamics connect substrate recognition to catalysis in protein kinase A.
Nat.Chem.Biol., 6, 2010
4FFV
  • Download 4ffv
  • View 4ffv
Molmil generated image of 4ffv
CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV (DPP4, DPP-IV, CD26) IN COMPLEX WITH 11A19 FAB
Descriptor:Dipeptidyl peptidase 4, 11A19 Fab light chain, 11A19 Fab heavy chain
Authors:Wang, Z., Sudom, A., Walker, N.P., Min, X.
Deposit date:2012-06-01
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An Inhibitory Antibody Against DPP IV Improves Glucose Tolerance in vivo - Validation of Large Molecule Approach for DPP IV Inhibition
To be published
4FFW
  • Download 4ffw
  • View 4ffw
Molmil generated image of 4ffw
CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV (DPP4, DPP-IV, CD26) IN COMPLEX WITH FAB + SITAGLIPTIN
Descriptor:Dipeptidyl peptidase 4, Fab light chain, Fab heavy chain, ...
Authors:Wang, Z., Sudom, A., Walker, N.P., Min, X.
Deposit date:2012-06-01
Release date:2012-12-12
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An Inhibitory Antibody Against DPP IV Improves Glucose Tolerance in vivo - Validation of Large Molecule Approach for DPP IV Inhibition
To be published
4NHJ
  • Download 4nhj
  • View 4nhj
Molmil generated image of 4nhj
CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE RSTA DNA-BINDING DOMAIN IN COMPLEX WITH RSTA BOX
Descriptor:DNA-binding transcriptional regulator RstA, 5'-D(*GP*GP*TP*TP*GP*TP*AP*CP*AP*TP*TP*CP*CP*GP*TP*TP*AP*CP*TP*CP*CP*CP*T)-3', 5'-D(*CP*AP*GP*GP*GP*AP*GP*TP*AP*AP*CP*GP*GP*AP*AP*TP*GP*TP*AP*CP*AP*AP*C)-3'
Authors:Li, Y.C., Hsiao, C.D.
Deposit date:2013-11-05
Release date:2014-07-16
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
4NIC
  • Download 4nic
  • View 4nic
Molmil generated image of 4nic
CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE RSTA BEF3-ACTIVATED N-TERMINAL RECEIVER DOMAIN
Descriptor:DNA-binding transcriptional regulator RstA, MAGNESIUM ION, BERYLLIUM TRIFLUORIDE ION
Authors:Li, Y.C., Hsiao, C.D.
Deposit date:2013-11-06
Release date:2014-07-16
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
5JJA
  • Download 5jja
  • View 5jja
Molmil generated image of 5jja
CRYSTAL STRUCTURE OF A PP2A B56GAMMA/BUBR1 COMPLEX
Descriptor:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Authors:Wang, Z., Wang, J., Rao, Z., Xu, W.
Deposit date:2016-04-22
Release date:2016-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Protein Cell, 7, 2016
2MEY
  • Download 2mey
  • View 2mey
Molmil generated image of 2mey
RDC REFINED SOLUTION STRUCTURE OF BLO T 5.
Descriptor:Mite allergen Blo t 5
Authors:Naik, M.T., Huang, T.
Deposit date:2013-10-02
Release date:2014-11-05
Method:SOLUTION NMR
Cite:NMR structure note: Blo t 5 from Blomia Tropicalis
To be Published