Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7OJI
DownloadVisualize
BU of 7oji by Molmil
ABCG2 topotecan turnover-2 state
Descriptor: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
Authors:Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P.
Deposit date:2021-05-16
Release date:2021-07-21
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
7OJH
DownloadVisualize
BU of 7ojh by Molmil
ABCG2 topotecan turnover-1 state
Descriptor: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
Authors:Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P.
Deposit date:2021-05-15
Release date:2021-07-21
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
7BKQ
DownloadVisualize
BU of 7bkq by Molmil
CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-01-17
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
4JVS
DownloadVisualize
BU of 4jvs by Molmil
Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3
Descriptor: ACETIC ACID, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Yu, Q, Yao, Q, Wang, D.-C, Shao, F.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.783 Å)
Cite:Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
7NGA
DownloadVisualize
BU of 7nga by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-08
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NIQ
DownloadVisualize
BU of 7niq by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-13
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NIC
DownloadVisualize
BU of 7nic by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-11
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
6G1X
DownloadVisualize
BU of 6g1x by Molmil
CryoEM structure of the MDA5-dsRNA filament with 91-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-22
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1S
DownloadVisualize
BU of 6g1s by Molmil
CryoEM structure of the MDA5-dsRNA filament with 87-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-21
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G19
DownloadVisualize
BU of 6g19 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 74-degree helical twist
Descriptor: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-03-20
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKM
DownloadVisualize
BU of 6gkm by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H61
DownloadVisualize
BU of 6h61 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-07-25
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GJZ
DownloadVisualize
BU of 6gjz by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with AMPPNP
Descriptor: Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-17
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKH
DownloadVisualize
BU of 6gkh by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-05-21
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H66
DownloadVisualize
BU of 6h66 by Molmil
CryoEM structure of the MDA5-dsRNA filament with 93 degree twist and without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ...
Authors:Yu, Q, Qu, K, Modis, Y.
Deposit date:2018-07-26
Release date:2018-11-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
5JHE
DownloadVisualize
BU of 5jhe by Molmil
The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
Descriptor: Peptidyl-prolyl cis-trans isomerase CYP7
Authors:Yu, Q, Xu, L.
Deposit date:2016-04-20
Release date:2017-04-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
To Be Published
7OJ8
DownloadVisualize
BU of 7oj8 by Molmil
ABCG2 E1S turnover-2 state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ...
Authors:Ni, D, Yu, Q, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P.
Deposit date:2021-05-14
Release date:2021-07-21
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Nat Commun, 12, 2021
8BI0
DownloadVisualize
BU of 8bi0 by Molmil
ABCG2 turnover-2 state with tariquidar bound
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ...
Authors:Yu, Q, Kowal, J, Tajkhorshid, E, Locher, K.P.
Deposit date:2022-11-01
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8BHT
DownloadVisualize
BU of 8bht by Molmil
ABCG2 turnover-1 state with tariquidar bound
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ...
Authors:Yu, Q, Kowal, J, Tajkhorshid, E, Locher, K.P.
Deposit date:2022-10-31
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2.
Proc.Natl.Acad.Sci.USA, 120, 2023
7BKP
DownloadVisualize
BU of 7bkp by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y.
Deposit date:2021-01-16
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
3R2W
DownloadVisualize
BU of 3r2w by Molmil
Crystal Structure of UDP-glucose Pyrophosphorylase of Homo Sapiens
Descriptor: UTP--glucose-1-phosphate uridylyltransferase
Authors:Zheng, X, Yu, Q.
Deposit date:2011-03-14
Release date:2012-02-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influences enzymatic activity.
Biochem.J., 442, 2012
6DRF
DownloadVisualize
BU of 6drf by Molmil
Structure of human Retinal Degeneration 3(RD3) Protein
Descriptor: Protein RD3
Authors:Yu, Q, Lim, S, Peshenko, I, Cudia, D, Dizhoor, A.M, Ames, J.B.
Deposit date:2018-06-11
Release date:2019-02-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle.
J. Biol. Chem., 294, 2019
7KL5
DownloadVisualize
BU of 7kl5 by Molmil
Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues: Phe4246 to Val4271
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Calmodulin-1, ...
Authors:Fisher, A.J, Ames, J.B, Yu, Q.
Deposit date:2020-10-29
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site.
Biochemistry, 60, 2021
6BHN
DownloadVisualize
BU of 6bhn by Molmil
Red Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Descriptor: Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Yu, Q, Lim, S, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4UUQ
DownloadVisualize
BU of 4uuq by Molmil
Crystal structure of human mono-glyceride lipase in complex with SAR127303
Descriptor: 4-({[(4-chlorophenyl)sulfonyl]amino}methyl)piperidine-1-carboxylic acid, MONOGLYCERIDE LIPASE
Authors:Griebel, G, Pichat, P, Beeske, S, Leroy, T, Redon, N, Francon, D, Bert, L, Even, L, Lopez-Grancha, M, Tolstykh, T, Sun, F, Yu, Q, Brittain, S, Arlt, H, He, T, Zhang, B, Wiederschain, D, Bertrand, T, Houtman, J, Rak, A, Vallee, F, Michot, N, Auge, F, Menet, V, Bergis, O.E, George, P, Avenet, P, Mikol, V, Didier, M, Escoubet, J.
Deposit date:2014-07-30
Release date:2015-01-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Selective Blockade of the Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol Impairs Learning and Memory Performance While Producing Antinociceptive Activity in Rodents.
Sci.Rep., 5, 2015

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon