Author results

2KLM
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SOLUTION STRUCTURE OF L11 WITH SAXS AND RDC
分子名称:50S ribosomal protein L11
著者Wang, J., Zuo, X., Yu, P., Schwieters, C.D., Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2011-07-13
実験手法SOLUTION SCATTERING, SOLUTION NMR
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
1NOY
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DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX
分子名称:DNA (5'-D(*TP*TP*T)-3'), PROTEIN (DNA POLYMERASE (E.C.2.7.7.7)), ZINC ION, ...
著者Wang, J., Yu, P., Lin, T.C., Konigsberg, W.H., Steitz, T.A.
登録日1996-02-16
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.
Biochemistry, 35, 1996
1NOZ
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T4 DNA POLYMERASE FRAGMENT (RESIDUES 1-388) AT 110K
分子名称:DNA POLYMERASE
著者Wang, J., Yu, P., Lin, T.C., Konigsberg, W.H., Steitz, T.A.
登録日1996-02-16
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.
Biochemistry, 35, 1996
1OP1
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SOLUTION NMR STRUCTURE OF DOMAIN 1 OF RECEPTOR ASSOCIATED PROTEIN
分子名称:Alpha-2-macroglobulin receptor-associated protein precursor
著者Wu, Y., Migliorini, M., Yu, P., Strickland, D.K., Wang, Y.-X.
登録日2003-03-04
公開日2003-08-26
最終更新日2017-02-08
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignments of domain 1 of receptor associated protein.
J.Biomol.Nmr, 26, 2003
1OV2
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ENSEMBLE OF THE SOLUTION STRUCTURES OF DOMAIN ONE OF RECEPTOR ASSOCIATED PROTEIN
分子名称:Alpha-2-macroglobulin receptor-associated protein precursor
著者Wu, Y., Migliorini, M., Yu, P., Strickland, D.K., Wang, Y.X.
登録日2003-03-25
公開日2004-04-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignments of domain 1 of receptor associated protein.
J.Biomol.Nmr, 26, 2003
1S2F
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AVERAGE SOLUTION STRUCTURE OF A PSEUDO-5'-SPLICE SITE FROM THE NEGATIVE REGULATOR OF SPLICING OF ROUS SARCOMA VIRUS
分子名称:5'-R(*GP*GP*GP*GP*AP*GP*UP*GP*GP*UP*UP*UP*GP*UP*AP*UP*CP*CP*UP*UP*CP*CP*C)-3'
著者Cabello-Villegas, J., Giles, K.E., Soto, A.M., Yu, P., Beemon, K.L., Wang, Y.X.
登録日2004-01-08
公開日2004-08-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the pseudo-5' splice site of a retroviral splicing suppressor.
Rna, 10, 2004
1S34
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SOLUTION STRUCTURE OF RESIDUES 907-929 FROM ROUS SARCOMA VIRUS
分子名称:5'-R(*GP*GP*GP*GP*AP*GP*UP*GP*GP*UP*UP*UP*GP*UP*AP*UP*CP*CP*UP*UP*CP*CP*C)-3'
著者Cabello-Villegas, J., Giles, K.E., Soto, A.M., Yu, P., Beemon, K.L., Wang, Y.X.
登録日2004-01-12
公開日2004-08-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the pseudo-5' splice site of a retroviral splicing suppressor.
Rna, 10, 2004
2E34
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L11 STRUCTURE WITH RDC AND RG REFINEMENT
分子名称:50S ribosomal protein L11
著者Lee, D., Walsh, J.D., Yu, P., Markus, M.A., Choli-Papadopoulous, T., Schwieters, C.D., Krueger, S., Draper, D.E., Wang, Y.X.
登録日2006-11-20
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes
J.Mol.Biol., 367, 2007
2E35
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THE MINIMIZED AVERAGE STRUCTURE OF L11 WITH RG REFINEMENT
分子名称:50S ribosomal protein L11
著者Lee, D., Walsh, J.D., Yu, P., Markus, M.A., Choli-Papadopoulous, T., Schwieters, C.D., Krueger, S., Draper, D.E., Wang, Y.X.
登録日2006-11-20
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes
J.Mol.Biol., 367, 2007
2E36
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L11 WITH SANS REFINEMENT
分子名称:50S ribosomal protein L11
著者Lee, D., Walsh, J.D., Yu, P., Markus, M.A., Choli-Papadopoulous, T., Schwieters, C.D., Krueger, S., Draper, D.E., Wang, Y.X.
登録日2006-11-20
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes
J.Mol.Biol., 367, 2007
2H8W
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SOLUTION STRUCTURE OF RIBOSOMAL PROTEIN L11
分子名称:50S ribosomal protein L11
著者Lee, D., Walsh, J.D., Yu, P., Choli-Papadopoulou, T., Krueger, S., Draper, D., Wang, Y.-X.
登録日2006-06-08
公開日2007-02-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Structure of Free L11 and Functional Dynamics of L11 in Free, L11-rRNA(58 nt) Binary and L11-rRNA(58 nt)-thiostrepton Ternary Complexes.
J.Mol.Biol., 367, 2007
2KLJ
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SOLUTION STRUCTURE OF GAMMAD-CRYSTALLIN WITH RDC AND SAXS
分子名称:Gamma-crystallin D
著者Wang, J., Zuo, X., Yu, P., Byeon, I., Jung, J., Gronenborn, A.M., Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2011-07-13
実験手法SOLUTION SCATTERING, SOLUTION NMR
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KLK
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SOLUTION STRUCTURE OF GB1 A34F MUTANT WITH RDC AND SAXS
分子名称:IMMUNOGLOBULIN G-BINDING PROTEIN G
著者Wang, J., Zuo, X., Yu, P., Byeon, I.L., Jung, J., Schwieters, C.D., Gronenborn, A.M., Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2011-07-13
実験手法SOLUTION SCATTERING, SOLUTION NMR
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KRL
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THE ENSEMBLE OF THE SOLUTION GLOBAL STRUCTURES OF THE 102-NT RIBOSOME BINDING STRUCTURE ELEMENT OF THE TURNIP CRINKLE VIRUS 3' UTR RNA
分子名称:RNA (102-MER)
著者Zuo, X., Wang, J., Yu, P., Eyler, D., Xu, H., Starich, M., Tiede, D., Simon, A., Kasprzak, W., Schwieters, C., Shapiro, B.
登録日2009-12-18
公開日2011-02-09
最終更新日2011-07-13
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus.
Proc.Natl.Acad.Sci.USA, 107, 2010
2P01
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THE STRUCTURE OF RECEPTOR-ASSOCIATED PROTEIN(RAP)
分子名称:Alpha-2-macroglobulin receptor-associated protein
著者Lee, D., Walsh, J.D., Migliorini, M., Yu, P., Cai, T., Schwieters, C.D., Krueger, S., Strickland, D.K., Wang, Y.X.
登録日2007-02-28
公開日2007-08-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structure of receptor-associated protein (RAP).
Protein Sci., 16, 2007
2P03
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THE STRUCTURE OF RECEPTOR-ASSOCIATED PROTEIN(RAP)
分子名称:Alpha-2-macroglobulin receptor-associated protein
著者Lee, D., Walsh, J.D., Migliorini, M., Yu, P., Cai, T., Schwieters, C.D., Krueger, S., Strickland, D.K., Wang, Y.X.
登録日2007-02-28
公開日2007-08-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structure of receptor-associated protein (RAP).
Protein Sci., 16, 2007
4AN2
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CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.
分子名称:DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, [3,4-BIS(FLUORANYL)-2-[(2-FLUORANYL-4-IODANYL-PHENYL)AMINO]PHENYL]-[3-OXIDANYL-3-[(2S)-PIPERIDIN-2-YL]AZETIDIN-1-YL]METHANONE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.
登録日2012-03-14
公開日2012-12-19
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward Xl518 (Gdc-0973)
Acs Med.Chem.Lett., 3, 2012
4AN3
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CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.
分子名称:DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.
登録日2012-03-15
公開日2012-12-19
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward Xl518 (Gdc-0973)
Acs Med.Chem.Lett., 3, 2012
4AN9
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CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.
分子名称:DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION, ...
著者Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.
登録日2012-03-16
公開日2012-12-19
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward Xl518 (Gdc-0973)
Acs Med.Chem.Lett., 3, 2012
4ANB
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CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.
分子名称:DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, [3-(AMINOMETHYL)-3-OXIDANYL-AZETIDIN-1-YL]-[3,4-BIS(FLUORANYL)-2-[(2-FLUORANYL-4-IODANYL-PHENYL)AMINO]PHENYL]METHANONE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.
登録日2012-03-16
公開日2012-12-19
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward Xl518 (Gdc-0973)
Acs Med.Chem.Lett., 3, 2012
4ALU
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BENZOFUROPYRIMIDINONE INHIBITORS OF PIM-1
分子名称:SERINE/THREONINE-PROTEIN KINASE PIM-1, IMIDAZOLE, 8-bromo-2-(2-chlorophenyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one
著者Stout, T.J., Adams, L.
登録日2012-03-05
公開日2013-01-16
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ALV
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BENZOFUROPYRIMIDINONE INHIBITORS OF PIM-1
分子名称:SERINE/THREONINE-PROTEIN KINASE PIM-1, IMIDAZOLE, 8-bromo-2-{2-chloro-4-[(piperidin-4-ylmethyl)amino]phenyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one
著者Stout, T.J., Adams, L.
登録日2012-03-05
公開日2013-01-16
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ALW
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BENZOFUROPYRIMIDINONE INHIBITORS OF PIM-1
分子名称:PIM-1 KINASE, IMIDAZOLE, 8-BROMANYL-2-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE
著者Stout, T.J., Adams, L.
登録日2012-03-05
公開日2013-01-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ANM
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COMPLEX OF CK2 WITH A CDC7 INHIBITOR
分子名称:CASEIN KINASE II SUBUNIT ALPHA, 8-BROMANYL-2-[[(3S)-3-OXIDANYLPYRROLIDIN-1-YL]METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE
著者Stout, T.J.
登録日2012-03-20
公開日2012-05-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of Xl413, a Potent and Selective Cdc7 Inhibitor.
Bioorg.Med.Chem.Lett., 22, 2012
4BBE
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AMINOALKYLPYRIMIDINE INHIBITOR COMPLEXES WITH JAK2
分子名称:TYROSINE-PROTEIN KINASE JAK2, N-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
著者Li, J.
登録日2012-09-21
公開日2012-11-21
最終更新日2012-12-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Sar and in Vivo Evaluation of 4-Aryl-2-Aminoalkylpyrimidines as Potent and Selective Janus Kinase 2 (Jak2) Inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
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