Author results

5L73
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MAM DOMAIN OF HUMAN NEUROPILIN-1
Descriptor:Neuropilin-1, CALCIUM ION, BICINE, ...
Authors:Yelland, T., Djordjevic, S.
Deposit date:2016-06-01
Release date:2016-10-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture.
Structure, 24, 2016
7AJK
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CRYSTAL STRUCTURE OF CRYI-B RAC1 COMPLEX
Descriptor:Ras-related C3 botulinum toxin substrate 1, CYFIP-related Rac1 interactor B, MAGNESIUM ION, ...
Authors:Yelland, T., Anh, L., Insall, R., Machesky, L., Ismail, S.
Deposit date:2020-09-29
Release date:2020-11-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the CRYI-B Rac1 complex
To Be Published
7AJL
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CYRSTAL STRUCTURE OF CYRI-B/FAM49B
Descriptor:CYFIP-related Rac1 interactor B
Authors:Yelland, T., Anh, H., Insall, R., Machesky, L., Ismail, S.
Deposit date:2020-09-29
Release date:2020-11-18
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Cyrstal structure of CYRI-B/Fam49B
To Be Published
6FMC
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NEUROPILIN1-B1 DOMAIN IN COMPLEX WITH EG01377, 0.9 ANGSTROM STRUCTURE
Descriptor:Neuropilin-1, (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid
Authors:Yelland, T., Djordjevic, S., Fotinou, K., Selwood, D., Zachary, I., Frankel, P.
Deposit date:2018-01-30
Release date:2018-10-17
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
6FMF
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NEUROPILIN-1 B1 DOMAIN IN COMPLEX WITH EG01377; 2.8 ANGSTROM STRUCTURE
Descriptor:Neuropilin-1, (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, trifluoroacetic acid
Authors:Yelland, T., Djordjevic, S., Selwood, D., Zachary, I., Frankel, P.
Deposit date:2018-01-31
Release date:2018-10-17
Method:X-RAY DIFFRACTION (2.811 Å)
Cite:Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
6H6A
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CRYSTAL STRUCTURE OF UNC119 IN COMPLEX WITH LCK PEPTIDE
Descriptor:Protein unc-119 homolog A, GLY-CYS-GLY-CYS-SER-SER, GLYCEROL, ...
Authors:Yelland, T., ElMaghloob, Y., McIlwraith, M., Stephen, L., Ismail, S.
Deposit date:2018-07-26
Release date:2018-09-26
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK.
Dev.Cell, 47, 2018
5IJR
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH ARG-1 LIGAND.
Descriptor:Neuropilin-1, L-HOMOARGININE, DIMETHYL SULFOXIDE
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-03-02
Release date:2017-03-29
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
5IYY
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH ARG-4 LIGAND.
Descriptor:Neuropilin-1, N~2~-[(benzyloxy)carbonyl]-L-arginine
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-03-24
Release date:2017-04-05
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
5J1X
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH ARG-5 LIGAND.
Descriptor:Neuropilin-1, N~2~-(tert-butoxycarbonyl)-L-arginine, DIMETHYL SULFOXIDE
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-03-29
Release date:2017-04-05
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
5JGI
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH M45 COMPOUND
Descriptor:Neuropilin-1, N-ALPHA-L-ACETYL-ARGININE
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-04-20
Release date:2017-05-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
5JGQ
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH ARG-7 LIGAND.
Descriptor:Neuropilin-1, DIMETHYL SULFOXIDE, N~2~-(benzenecarbonyl)-L-arginine
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-04-20
Release date:2017-05-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
5JHK
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X-RAY STRUCTURE OF NEUROPILIN-1 B1 DOMAIN COMPLEXED WITH ARG-6 LIGAND.
Descriptor:Neuropilin-1, N-(benzenecarbonyl)glycyl-L-arginine
Authors:Fotinou, C., Rana, R., Djordjevic, S., Yelland, T.
Deposit date:2016-04-21
Release date:2017-05-24
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
6TDB
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NEUROPILIN2-B1 DOMAIN IN A COMPLEX WITH THE C-TERMINAL VEGFB167 PEPTIDE
Descriptor:Neuropilin-2, C-terminal VEGFB167 peptide, 1,2-ETHANEDIOL, ...
Authors:Eldrid, C., Yu, L., Yelland, T., Fotinou, C., Djordjevic, S.
Deposit date:2019-11-08
Release date:2020-11-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:NRP2-b1 domain in a complex with the C-terminal VEGFB167 peptide
To Be Published
3ZIW
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CLOSTRIDIUM PERFRINGENS ENTEROTOXIN, D48A MUTATION AND N-TERMINAL 37 RESIDUES DELETED
Descriptor:HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL
Authors:Yelland, T., Naylor, C.E., Savva, C.G., Basak, A.K.
Deposit date:2013-01-14
Release date:2014-01-29
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
3ZIX
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CLOSTRIDIUM PERFRINGENS ENTEROTOXIN WITH THE N-TERMINAL 37 RESIDUES DELETED
Descriptor:HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL
Authors:Yelland, T., Naylor, C.E., Savva, C.G., Basak, A.K.
Deposit date:2013-01-14
Release date:2014-01-29
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
5DN2
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HUMAN NRP2 B1 DOMAIN IN COMPLEX WITH THE PEPTIDE CORRESPONDING TO THE C-TERMINUS OF VEGF-A
Descriptor:Neuropilin-2, Vascular endothelial growth factor A, 1,4-DIETHYLENE DIOXIDE, ...
Authors:Tsai, Y.C.I., Frankel, P., Fotinou, C., Rana, R., Zachary, I., Djordjevic, S.
Deposit date:2015-09-09
Release date:2016-07-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.
Febs J., 283, 2016
171916
PDB entries from 2020-12-02