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1QQK
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
分子名称:FIBROBLAST GROWTH FACTOR 7
著者Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L.
登録日1999-06-07
公開日2000-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQL
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
分子名称:FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
著者Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L.
登録日1999-06-07
公開日2000-01-14
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1K9O
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CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX
分子名称:ALASERPIN, TRYPSIN II ANIONIC
著者Ye, S., Cech, A.L., Belmares, R., Bergstrom, R.C., Tong, Y., Corey, D.R., Kanost, M.R., Goldsmith, E.J.
登録日2001-10-29
公開日2001-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of a Michaelis serpin-protease complex.
Nat.Struct.Biol., 8, 2001
1P74
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CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE
分子名称:Shikimate 5-dehydrogenase
著者Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E.
登録日2003-04-30
公開日2003-08-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode
J.Bacteriol., 185, 2003
1P77
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CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE
分子名称:Shikimate 5-dehydrogenase, ACETATE ION, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE
著者Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E.
登録日2003-04-30
公開日2003-08-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode
J.Bacteriol., 185, 2003
1R8J
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CRYSTAL STRUCTURE OF CIRCADIAN CLOCK PROTEIN KAIA FROM SYNECHOCOCCUS ELONGATUS
分子名称:KaiA
著者Ye, S., Vakonakis, I., Sacchettini, J.C., LiWang, A.C.
登録日2003-10-26
公開日2004-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of circadian clock protein KaiA from Synechococcus elongatus
J.Biol.Chem., 279, 2004
2FY8
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CRYSTAL STRUCTURE OF MTHK RCK DOMAIN IN ITS LIGAND-FREE GATING-RING FORM
分子名称:Calcium-gated potassium channel mthK
著者Ye, S., Jiang, Y.
登録日2006-02-07
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Crystal Structures of a Ligand-free MthK Gating Ring: Insights into the Ligand Gating Mechanism of K(+) Channels.
Cell(Cambridge,Mass.), 126, 2006
2IC1
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CRYSTAL STRUCTURE OF HUMAN CYSTEINE DIOXYGENASE IN COMPLEX WITH SUBSTRATE CYSTEINE
分子名称:Cysteine dioxygenase type 1, FE (II) ION, CYSTEINE
著者Ye, S., Wu, X., Wei, L., Tang, D., Sun, P., Rao, Z.
登録日2006-09-12
公開日2006-12-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An Insight into the Mechanism of Human Cysteine Dioxygenase: KEY ROLES OF THE THIOETHER-BONDED TYROSINE-CYSTEINE COFACTOR.
J.Biol.Chem., 282, 2007
3LDC
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HIGH RESOLUTION OPEN MTHK PORE STRUCTURE CRYSTALLIZED IN 100 MM K+
分子名称:Calcium-gated potassium channel mthK, POTASSIUM ION
著者Ye, S.
登録日2010-01-12
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore.
Nat.Struct.Mol.Biol., 17, 2010
3LDD
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HIGH RESOLUTION OPEN MTHK PORE STRUCTURE CRYSTALLIZED IN 100 MM K+ AND FURTHER SOAKED IN 99 MM NA+/1 MM K+.
分子名称:Calcium-gated potassium channel mthK, POTASSIUM ION
著者Ye, S.
登録日2010-01-12
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore.
Nat.Struct.Mol.Biol., 17, 2010
3LDE
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HIGH RESOLUTION OPEN MTHK PORE STRUCTURE CRYSTALLIZED IN 100 MM K+ AND FURTHER SOAKED IN 100 MM NA+.
分子名称:Calcium-gated potassium channel mthK, SODIUM ION
著者Ye, S.
登録日2010-01-12
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore.
Nat.Struct.Mol.Biol., 17, 2010
4Y0Y
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TRYPSIN IN COMPLEX WITH WITH BPTI
分子名称:Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B.
登録日2015-02-06
公開日2015-06-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
4Y0Z
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TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT AMINOBUTYRIC ACID
分子名称:Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B.
登録日2015-02-06
公開日2015-06-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
4Y10
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TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT (2S)-2-AMINO-4,4-DIFLUOROBUTANOIC ACID
分子名称:Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B.
登録日2015-02-06
公開日2015-06-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
4Y11
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TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT (2S)-2-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID
分子名称:Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B.
登録日2015-02-06
公開日2015-06-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
5Y56
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FC MUTANT (K392D/K409D/D399K)
分子名称:Immunoglobulin gamma-1 heavy chain, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
著者Ye, S., Xu, T., Yu, J., Wang, X., Xu, T., Jin, Q., Duan, J., Wu, J., Wu, H.
登録日2017-08-07
公開日2017-09-13
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.653 Å)
主引用文献A rational approach to enhancing antibody Fc homodimer formation for robust production of antibody mixture in a single cell line
J. Biol. Chem., 292, 2017
5H0N
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CRYSTAL STRUCTURE OF HIV-1 FUSION INHIBITOR MT-WQ-IDL BOUND TO GP41 NHR
分子名称:HIV-1 gp41 NHR, HIV-1 fusion inhibitor MT-WQ-IDL
著者Zhu, Y., Ye, S., Zhang, R.
登録日2016-10-06
公開日2016-11-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors
J. Virol., 91, 2017
1J04
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STRUCTURAL MECHANISM OF ENZYME MISTARGETING IN HEREDITARY KIDNEY STONE DISEASE IN VITRO
分子名称:alanine--glyoxylate aminotransferase, (AMINOOXY)ACETIC ACID, GLYCEROL
著者Zhang, X., Djordjevic, S., Bartlam, M., Ye, S., Rao, Z., Danpure, C.J.
登録日2002-10-30
公開日2003-11-11
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.
Acta Crystallogr.,Sect.F, 66, 2010
1ZD7
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1.7 ANGSTROM CRYSTAL STRUCTURE OF POST-SPLICING FORM OF A DNAE INTEIN FROM SYNECHOCYSTIS SP. PCC 6803
分子名称:DNA polymerase III alpha subunit, SULFATE ION
著者Sun, P., Ye, S., Ferrandon, S., Evans, T.C., Xu, M.Q., Rao, Z.
登録日2005-04-14
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
1ZDE
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1.95 ANGSTROM CRYSTAL STRUCTURE OF A DNAE INTEIN PRECURSOR FROM SYNECHOCYSTIS SP. PCC 6803
分子名称:DNA polymerase III alpha subunit, ZINC ION, CALCIUM ION
著者Sun, P., Ye, S., Ferrandon, S., Evans, T.C., Xu, M.Q., Rao, Z.
登録日2005-04-14
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
3EB7
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CRYSTAL STRUCTURE OF INSECTICIDAL DELTA-ENDOTOXIN CRY8EA1 FROM BACILLUS THURINGIENSIS AT 2.2 ANGSTROMS RESOLUTION
分子名称:Insecticidal Delta-Endotoxin Cry8Ea1, SULFATE ION, ACETATE ION
著者Guo, S., Ye, S., Song, F., Zhang, J., Wei, L., Shu, C.L.
登録日2008-08-27
公開日2008-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela.
J.Struct.Biol., 168, 2009
3JU5
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CRYSTAL STRUCTURE OF DIMERIC ARGININE KINASE AT 1.75-A RESOLUTION
分子名称:Arginine kinase, MAGNESIUM ION
著者Wu, X., Ye, S., Guo, S., Yan, W., Bartlam, M., Rao, Z.
登録日2009-09-14
公開日2009-09-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity
Faseb J., 24, 2010
3JU6
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CRYSTAL STRUCTURE OF DIMERIC ARGININE KINASE IN COMPLEX WITH AMPPNP AND ARGININE
分子名称:Arginine kinase, ARGININE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wu, X., Ye, S., Guo, S., Yan, W., Bartlam, M., Rao, Z.
登録日2009-09-14
公開日2009-09-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity
Faseb J., 24, 2010
4NJL
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CRYSTAL STRUCTURE OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS S2 PROTEIN FUSION CORE
分子名称:S protein, TRIETHYLENE GLYCOL
著者Zhu, Y., Lu, L., Qin, L., Ye, S., Jiang, S., Zhang, R.
登録日2013-11-10
公開日2014-02-19
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Nat Commun, 5, 2014
4PV7
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COCRYSTAL STRUCTURE OF DIPEPTIDYL-PEPTIDASE 4 WITH AN INDOLE SCAFFOLD INHIBITOR
分子名称:Dipeptidyl peptidase 4 soluble form, 1-[2-(2,4-dichlorophenyl)-1-(methylsulfonyl)-1H-indol-3-yl]methanamine
著者Xiao, P., Guo, R., Huang, S., Cui, H., Ye, S., Zhang, Z.
登録日2014-03-15
公開日2015-03-18
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold
Chin.Chem.Lett., 25, 2014