Author results

1A6X
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STRUCTURE OF THE APO-BIOTIN CARBOXYL CARRIER PROTEIN (APO-BCCP87) OF ESCHERICHIA COLI ACETYL-COA CARBOXYLASE, NMR, 49 STRUCTURES
分子名称:APO-BIOTIN CARBOXYL CARRIER PROTEIN OF ACETYL-COA CARBOXYLASE
著者Yao, X., Wei, D., Soden Junior, C., Summers, M.F., Beckett, D.
登録日1998-03-04
公開日1998-10-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the carboxy-terminal fragment of the apo-biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase.
Biochemistry, 36, 1997
1B8T
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SOLUTION STRUCTURE OF THE CHICKEN CRP1
分子名称:PROTEIN (CRP1), ZINC ION
著者Yao, X., Perez-Alvarado, G.C., Louis, H.A., Pomies, P., Hatt, C., Summers, M.F., Beckerle, M.C.
登録日1999-02-02
公開日1999-05-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the chicken cysteine-rich protein, CRP1, a double-LIM protein implicated in muscle differentiation.
Biochemistry, 38, 1999
3VGY
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P321
分子名称:Envelope glycoprotein gp160, CP32M, SULFATE ION
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-08-22
公開日2012-06-13
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.034 Å)
主引用文献Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VH7
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P21
分子名称:Envelope glycoprotein gp160, CP32M, MAGNESIUM ION
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-08-23
公開日2012-06-13
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.019 Å)
主引用文献Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VIE
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HIV-GP41 FUSION INHIBITOR SIFUVIRTIDE
分子名称:Envelope glycoprotein gp160, Sifuvirtide
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-09-29
公開日2012-01-18
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012
3VTQ
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NOVEL HIV FUSION INHIBITOR
分子名称:Envelope glycoprotein gp160, fusion inhibitor MT-Sifuvirtide
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2012-06-02
公開日2013-06-26
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal structure of a novel HIV fusion inhibitor
To be Published
3W19
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POTENT HIV FUSION INHIBITOR CP32M-2
分子名称:Transmembrane protein gp41, fusion inhibitor CP32M-2
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2012-11-13
公開日2013-12-11
実験手法X-RAY DIFFRACTION (1.278 Å)
主引用文献Optimization of novel anti-HIV fusion inhibitor
To be Published
4I2L
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NEW HIV ENTRY INHIBITOR MTSFT/T23 COMPLEX
分子名称:GP41, inhibitor MTSFT
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-11-22
公開日2014-01-22
実験手法X-RAY DIFFRACTION (1.426 Å)
主引用文献Potent antiviral activity of the novel HIV entry inhibitor MTSFT
To be Published
6J2Y
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SOLUTION STRUCTURE OF TRANSLATIONALLY CONTROLLED TUMOR PROTEIN FROM PHOTOSYNTHETIC MICROALGA NANNOCHLOROPSIS OCEANICA
分子名称:NoTCTP
著者Yao, X., Feng, Y.
登録日2019-01-03
公開日2019-03-13
実験手法SOLUTION NMR
主引用文献Solution structure of a unicellular microalgae-derived translationally controlled tumor protein revealed both conserved features and structural diversity.
Arch. Biochem. Biophys., 665, 2019
3VGX
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STRUCTURE OF GP41 T21/CP621-652
分子名称:Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2011-08-22
公開日2012-04-25
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
3VTP
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HIV FUSION INHIBITOR MT-C34
分子名称:Transmembrane protein gp41
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2012-06-02
公開日2012-08-22
最終更新日2014-01-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The M-T hook structure is critical for design of HIV-1 fusion inhibitors.
J.Biol.Chem., 287, 2012
3VU5
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SHORT PEPTIDE HIV ENTRY INHIBITOR SC22EK
分子名称:Transmembrane protein gp41, SC22, SULFATE ION, ...
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-06-19
公開日2012-12-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VU6
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SHORT PEPTIDE HIV ENTRY INHIBITOR MT-SC22EK WITH A M-T HOOK
分子名称:Transmembrane protein gp41, MTSC22, SULFATE ION
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-06-19
公開日2012-12-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.324 Å)
主引用文献Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
6JKK
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CRYSTAL STRUCTURE OF BUBR1 KINASE DOMAIN
分子名称:Mitotic checkpoint control protein kinase BUB1, GLYCEROL, DI(HYDROXYETHYL)ETHER
著者Lin, L., Ye, S., Huang, Y., Liu, X., Zhang, R., Yao, X.
登録日2019-03-01
公開日2019-06-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 29, 2019
6JKM
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CRYSTAL STRUCTURE OF BUBR1 KINASE DOMAIN
分子名称:Mitotic checkpoint control protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Lin, L., Ye, S., Huang, Y., Liu, X., Zhang, R., Yao, X.
登録日2019-03-01
公開日2019-06-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 29, 2019
3AQQ
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CRYSTAL STRUCTURE OF HUMAN CRHSP-24
分子名称:Calcium-regulated heat stable protein 1
著者Hou, H., Wang, F., Zhang, W., Wang, D., Li, X., Bartlam, M., Yao, X., Rao, Z.
登録日2010-11-17
公開日2010-12-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies
To be Published
3QZQ
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71D IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.7001 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3QZR
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71A IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.039 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3R0F
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT H133G IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-08
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.3083 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
6DCG
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DISCOVERY OF MK-8353: AN ORALLY BIOAVAILABLE DUAL MECHANISM ERK INHIBITOR FOR ONCOLOGY
分子名称:Mitogen-activated protein kinase 1, SULFATE ION, (3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)-N-(3-{6-[(propan-2-yl)oxy]pyridin-3-yl}-1H-indazol-5-yl)pyrrolidine-3-carboxamide
著者Boga, S.B., Deng, Y., Zhu, L., Nan, Y., Cooper, A., Shipps Jr., G.W., Doll, R., Shih, N., Zhu, H., Sun, R., Wang, T., Paliwal, S., Tsui, H., Gao, X., Yao, X., Desai, J., Wang, J., Alhassan, A.B., Kelly, J., Patel, M., Muppalla, K., Gudipati, S., Zhang, L., Buevich, A., Hesk, D., Carr, D., Dayananth, P., Mei, H., Cox, K., Sherborne, B., Hruza, A.W., Xiao, L., Jin, W., Long, B., Liu, G., Taylor, S.A., Kirschmeier, P., Windsor, W.T., Bishop, R., Samatar, A.A.
登録日2018-05-06
公開日2018-08-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.
ACS Med Chem Lett, 9, 2018
1G03
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NMR STRUCTURE OF N-TERMINAL DOMAIN OF HTLV-I CA1-134
分子名称:HTLV-I CAPSID PROTEIN
著者Cornilescu, C.C., Bouamr, F., Yao, X., Carter, C., Tjandra, N.
登録日2000-10-05
公開日2001-03-21
最終更新日2016-04-06
実験手法SOLUTION NMR
主引用文献Structural analysis of the N-terminal domain of the human T-cell leukemia virus capsid protein.
J.Mol.Biol., 306, 2001
1SI5
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PROTEASE-LIKE DOMAIN FROM 2-CHAIN HEPATOCYTE GROWTH FACTOR
分子名称:hepatocyte growth factor
著者Kirchhofer, D., Yao, X., Peek, M., Eigenbrot, C., Lipari, M.T., Billeci, K.L., Maun, H.R., Moran, P., Santell, L., Lazarus, R.A.
登録日2004-02-27
公開日2004-12-28
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling
J.Biol.Chem., 279, 2004
3R45
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STRUCTURE OF A CENP-A-HISTONE H4 HETERODIMER IN COMPLEX WITH CHAPERONE HJURP
分子名称:Histone H3-like centromeric protein A, Histone H4, Holliday junction recognition protein, ...
著者Hu, H., Liu, Y., Wang, M., Fang, J., Huang, H., Yang, N., Li, Y., Wang, J., Yao, X., Shi, Y., Li, G., Xu, R.M.
登録日2011-03-17
公開日2011-04-06
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Genes Dev., 25, 2011
4HHV
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CRYSTAL STRUCTURE OF CERAMIDE TRANSFER PROTEIN PLECKSTRIN HOMOLOGY DOMAIN
分子名称:Collagen type IV alpha-3-binding protein, SULFATE ION, GLYCEROL, ...
著者Prashek, J., Truong, T., Yao, X.
登録日2012-10-10
公開日2013-11-27
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Pleckstrin Homology Domain from the Ceramide Transfer Protein: Implications for Conformational Change upon Ligand Binding.
Plos One, 8, 2013
5HIN
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH 18L COMPOUND
分子名称:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
著者Huang, J., Wu, D., Lu, Q., Yao, X.
登録日2016-01-12
公開日2016-07-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L at 1.60 A resolution
To Be Published
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