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2WFL
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE
Descriptor:POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
3GZJ
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE COMPLEXED WITH 16-EPI-VELLOSIMINE
Descriptor:Polyneuridine-aldehyde esterase, 16-epi-Vellosimine
Authors:Yang, L., Hill, M., Wang, M., Panjikar, S., Stoeckigt, J.
Deposit date:2009-04-07
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFM
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE MUTANT (H244A)
Descriptor:POLYNEURIDINE ALDEHYDE ESTERASE
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
3P4Z
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TIME-DEPENDENT AND PROTEIN-DIRECTED IN SITU GROWTH OF GOLD NANOPARTICLES IN A SINGLE CRYSTAL OF LYSOZYME
Descriptor:Lysozyme C, GOLD ION, CHLORIDE ION, ...
Authors:Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y.-G., Yang, L., Robinson, H., Tan, L.H., Xing, H., Hou, C., Robertson, I.M., Zuo, J.-M., Lu, Y.
Deposit date:2010-10-07
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
3P64
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TIME-DEPENDENT AND PROTEIN-DIRECTED IN SITU GROWTH OF GOLD NANOPARTICLES IN A SINGLE CRYSTAL OF LYSOZYME
Descriptor:Lysozyme C, GOLD 3+ ION, GOLD ION, ...
Authors:Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y.-G., Yang, L., Robinson, H., Tan, L.H., Xing, H., Hou, C., Robertson, I.M., Zuo, J.-M., Lu, Y.
Deposit date:2010-10-11
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
3P65
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TIME-DEPENDENT AND PROTEIN-DIRECTED IN SITU GROWTH OF GOLD NANOPARTICLES IN A SINGLE CRYSTAL OF LYSOZYME
Descriptor:Lysozyme C, GOLD 3+ ION, GOLD ION, ...
Authors:Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y.-G., Yang, L., Robinson, H., Tan, L.H., Xing, H., Hou, C., Robertson, I.M., Zuo, J.-M., Lu, Y.
Deposit date:2010-10-11
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
3P66
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TIME-DEPENDENT AND PROTEIN-DIRECTED IN SITU GROWTH OF GOLD NANOPARTICLES IN A SINGLE CRYSTAL OF LYSOZYME
Descriptor:Lysozyme C, GOLD 3+ ION
Authors:Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y.-G., Yang, L., Robinson, H., Tan, L.H., Xing, H., Hou, C., Robertson, I.M., Zuo, J.-M., Lu, Y.
Deposit date:2010-10-11
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
3P68
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TIME-DEPENDENT AND PROTEIN-DIRECTED IN SITU GROWTH OF GOLD NANOPARTICLES IN A SINGLE CRYSTAL OF LYSOZYME
Descriptor:Lysozyme C, GOLD 3+ ION
Authors:Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y.-G., Yang, L., Robinson, H., Tan, L.H., Xing, H., Hou, C., Robertson, I.M., Zuo, J.-M., Lu, Y.
Deposit date:2010-10-11
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme.
Nat Nanotechnol, 6, 2011
2LS2
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE FIRST TRANSMEMBRANE DOMAIN FROM HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
2LS3
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE SECONDARY TRANSMEMBRANE DOMAIN FROM HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
2LS4
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE THIRD TRANSMEMBRANE DOMAIN FROM THE HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
3UPR
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HLA-B*57:01 COMPLEXED TO PEP-V AND ABACAVIR
Descriptor:HLA class I histocompatibility antigen, B-57 alpha chain, pep-V, ...
Authors:Pompeu, Y.A., Ostrov, D.A.
Deposit date:2011-11-18
Release date:2012-06-13
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proc.Natl.Acad.Sci.USA, 109, 2012
4IAQ
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH DIHYDROERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Dihydroergotamine
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4IAR
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH ERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Ergotamine, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4K9R
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SPORE PHOTOPRODUCT LYASE Y98F MUTANT
Descriptor:Spore photoproduct lyase, IRON/SULFUR CLUSTER, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium, ...
Authors:Yang, L., Nelson, R.S., Benjdia, A., Lin, G., Telser, J., Stoll, S., Schlichting, I., Li, L.
Deposit date:2013-04-20
Release date:2013-05-08
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A radical transfer pathway in spore photoproduct lyase.
Biochemistry, 52, 2013
4JZR
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STRUCTURE OF PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) WITH INHIBITORS
Descriptor:Egl nine homolog 1, NICKEL (II) ION, 2-(biphenyl-4-yl)-8-[(1-methyl-1H-imidazol-2-yl)methyl]-2,8-diazaspiro[4.5]decan-1-one, ...
Authors:Ma, Y., Yang, L.
Deposit date:2013-04-03
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors
Bioorg.Med.Chem., 21, 2013
4NQF
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CRYSTAL STRUCTURE OF HEPN DOMAIN PROTEIN
Descriptor:Nucleotidyltransferase
Authors:Padavannil, A., Jobichen, C., Sivaraman, J.
Deposit date:2013-11-25
Release date:2014-03-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants
Plos Pathog., 10, 2014
4C1W
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE COMPLEXED WITH 3'-SIALYLLACTOSE
Descriptor:NEURAMINIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2->3)-BETA-D-LYXO-HEXOPYRANOSYL-(1->4)HEXOPYRANOSE
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2013-08-14
Release date:2014-08-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Prevention of Influenza by Targeting Host Receptors Using Engineered Proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
4C1X
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE COMPLEXED WITH 6'-SIALYLLACTOSE
Descriptor:SIALIDASE A, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2013-08-14
Release date:2014-09-10
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural Characterization of the Carbohydrate-Binding Module of Nana Sialidase, a Pneumococcal Virulence Factor.
Bmc Struct.Biol., 15, 2015
4ZXK
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE
Descriptor:Sialidase A
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2015-05-20
Release date:2015-05-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Carbohydrate binding domain from Streptococcus pneumoniae NanA sialidase
To Be Published
4XT9
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RORGAMMA (263-509) COMPLEXED WITH GSK2435341A AND SRC2
Descriptor:Nuclear receptor ROR-gamma, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, ...
Authors:Wang, Y., Ma, Y.
Deposit date:2015-01-23
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
4ZN2
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GLYCOSYL HYDROLASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:PslG
Authors:Su, T., Liu, S., Gu, L.
Deposit date:2015-05-04
Release date:2016-01-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix
Cell Res., 25, 2015
4XE9
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CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH OPTACTIN
Descriptor:Sialidase B, (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE
Authors:Brear, P.
Deposit date:2014-12-23
Release date:2016-01-13
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB
To be published
4XJU
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CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH 4-ACETAMIDO-2-FLUORO-3-HYDROXY-6-[1,2-DIHYDROXYETHYL]-7,8-DIOXABICYCLO[3.2.1]OCTANE-1-CARBOXYLIC ACID
Descriptor:Sialidase B, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:Brear, P.
Deposit date:2015-01-09
Release date:2016-01-13
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:`The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB
To be published
4XJW
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CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH OPTACTIN AT PH 7.4 IN PBS WITH DMSO AS THE CRYOPROTECTANT
Descriptor:Sialidase B, (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, ...
Authors:Brear, P.
Deposit date:2015-01-09
Release date:2016-01-13
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:`The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB
To be published