Author results

4K9R
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SPORE PHOTOPRODUCT LYASE Y98F MUTANT
Descriptor:Spore photoproduct lyase, IRON/SULFUR CLUSTER, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium, ...
Authors:Yang, L., Nelson, R.S., Benjdia, A., Lin, G., Telser, J., Stoll, S., Schlichting, I., Li, L.
Deposit date:2013-04-20
Release date:2013-05-08
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A radical transfer pathway in spore photoproduct lyase.
Biochemistry, 52, 2013
2LS2
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE FIRST TRANSMEMBRANE DOMAIN FROM HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
2LS3
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE SECONDARY TRANSMEMBRANE DOMAIN FROM HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
2LS4
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1H CHEMICAL SHIFT ASSIGNMENTS FOR THE THIRD TRANSMEMBRANE DOMAIN FROM THE HUMAN COPPER TRANSPORT 1
Descriptor:High affinity copper uptake protein 1
Authors:Yang, L., Huang, Z., Li, F.
Deposit date:2012-04-20
Release date:2012-06-06
Method:SOLUTION NMR
Cite:Structural insights into the transmembrane domains of human copper transporter 1
To be Published
2WFL
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE
Descriptor:POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFM
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE MUTANT (H244A)
Descriptor:POLYNEURIDINE ALDEHYDE ESTERASE
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
3GZJ
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CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE COMPLEXED WITH 16-EPI-VELLOSIMINE
Descriptor:Polyneuridine-aldehyde esterase, 16-epi-Vellosimine
Authors:Yang, L., Hill, M., Wang, M., Panjikar, S., Stoeckigt, J.
Deposit date:2009-04-07
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
Angew.Chem.Int.Ed.Engl., 48, 2009
4C1X
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE COMPLEXED WITH 6'-SIALYLLACTOSE
Descriptor:SIALIDASE A, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2013-08-14
Release date:2014-09-10
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural Characterization of the Carbohydrate-Binding Module of Nana Sialidase, a Pneumococcal Virulence Factor.
Bmc Struct.Biol., 15, 2015
4ZXK
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE
Descriptor:Sialidase A
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2015-05-20
Release date:2015-05-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Carbohydrate binding domain from Streptococcus pneumoniae NanA sialidase
To Be Published
5WWW
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CRYSTAL STRUCTURE OF THE KH1 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(*GP*UP*UP*UP*AP*G)-3')
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWX
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CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), NICKEL (II) ION
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWZ
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CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
4C1W
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CARBOHYDRATE BINDING DOMAIN FROM STREPTOCOCCUS PNEUMONIAE NANA SIALIDASE COMPLEXED WITH 3'-SIALYLLACTOSE
Descriptor:NEURAMINIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2->3)-BETA-D-LYXO-HEXOPYRANOSYL-(1->4)HEXOPYRANOSE
Authors:Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
Deposit date:2013-08-14
Release date:2014-08-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Prevention of Influenza by Targeting Host Receptors Using Engineered Proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
5XEZ
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody, mAb1, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5XF1
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STRUCTURE OF THE FULL-LENGTH GLUCAGON CLASS B G PROTEIN-COUPLED RECEPTOR
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ...
Authors:Zhang, H., Qiao, A., Yang, D., Yang, L., Dai, A., de Graaf, C., Reedtz-Runge, S., Dharmarajan, V., Zhang, H., Han, G.W., Grant, T., Sierra, R., Weierstall, U., Nelson, G., Liu, W., Wu, Y., Ma, L., Cai, X., Lin, G., Wu, X., Geng, Z., Dong, Y., Song, G., Griffin, P., Lau, J., Cherezov, V., Yang, H., Hanson, M., Stevens, R., Jiang, H., Wang, M., Zhao, Q., Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5YQZ
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STRUCTURE OF THE GLUCAGON RECEPTOR IN COMPLEX WITH A GLUCAGON ANALOGUE
Descriptor:Glucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, H., Qiao, A., Yang, L., VAN EPS, N., Frederiksen, K., Yang, D., Dai, A., Cai, X., Zhang, H., Yi, C., Can, C., He, L., Yang, H., Lau, J., Ernst, O., Hanson, M., Stevens, R., Wang, M., Seedtz-Runge, S., Jiang, H., Zhao, Q., Wu, B.
Deposit date:2017-11-08
Release date:2018-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553, 2018
4IAQ
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH DIHYDROERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Dihydroergotamine
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4IAR
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT1B-BRIL IN COMPLEX WITH ERGOTAMINE (PSI COMMUNITY TARGET)
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Ergotamine, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
5YN5
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CRYSTAL STRUCTURE OF MERS-COV NSP10/NSP16 COMPLEX
Descriptor:nsp16 protein, nsp10 protein, ZINC ION
Authors:Wei, S.M., Yang, L., Ke, Z.H., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YN6
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CRYSTAL STRUCTURE OF MERS-COV NSP10/NSP16 COMPLEX BOUND TO SAM
Descriptor:nsp16 protein, nsp10 protein, S-ADENOSYLMETHIONINE, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YN8
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CRYSTAL STRUCTURE OF MERS-COV NSP16/NSP10 COMPLEX BOUND TO SAH
Descriptor:nsp16 protein, nsp10 protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Chen, Y., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNB
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CRYSTAL STRUCTURE OF MERS-COV NSP16/NSP10 COMPLEX BOUND TO SINEFUNGIN
Descriptor:nsp16 protein, nsp10 protein, SINEFUNGIN, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Chen, Y., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNF
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CRYSTAL STRUCTURE OF MERS-COV NSP16/NSP10 COMPLEX BOUND TO M7GPPPA
Descriptor:nsp16 protein, nsp10 protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Chen, Y., Guo, D.Y.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNI
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CRYSTAL STRUCTURE OF MERS-COV NSP16/NSP10 COMPLEX BOUND TO SAM AND M7GPPPG
Descriptor:nsp16 protein, nsp10 protein, S-ADENOSYLMETHIONINE, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Chen, Y., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNJ
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CRYSTAL STRUCTURE OF MERS-COV NSP16/NSP10 COMPLEX BOUND TO M7GPPPG
Descriptor:nsp16 protein, nsp10 protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ...
Authors:Wei, S.M., Yang, L., Ke, Z.H., Chen, Y., Guo, D.Y., Fan, C.P.
Deposit date:2017-10-24
Release date:2018-12-05
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published