Author results

1UJ1
  • Download 1uj1
  • View 1uj1
Molmil generated image of 1uj1
CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO)
分子名称:3C-like proteinase
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-07-25
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK2
  • Download 1uk2
  • View 1uk2
Molmil generated image of 1uk2
CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH8.0
分子名称:3C-LIKE PROTEINASE
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-08-14
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK3
  • Download 1uk3
  • View 1uk3
Molmil generated image of 1uk3
CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6
分子名称:3C-like proteinase
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-08-14
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK4
  • Download 1uk4
  • View 1uk4
Molmil generated image of 1uk4
CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) COMPLEXED WITH AN INHIBITOR
分子名称:3C-like proteinase, 5-mer peptide of inhibitor, CHLOROACETONE
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-08-14
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1WOF
  • Download 1wof
  • View 1wof
Molmil generated image of 1wof
CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR N1
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Rao, Z.
登録日2004-08-18
公開日2005-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMD
  • Download 2amd
  • View 2amd
Molmil generated image of 2amd
CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N9
分子名称:3C-like proteinase, N-(3-FUROYL)-D-VALYL-L-VALYL-N~1~-((1R,2Z)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-D-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-09
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMP
  • Download 2amp
  • View 2amp
Molmil generated image of 2amp
CRYSTAL STRUCTURE OF PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS MPRO IN COMPLEX WITH AN INHIBITOR N1
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-10
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2AMQ
  • Download 2amq
  • View 2amq
Molmil generated image of 2amq
CRYSTAL STRUCTURE OF SARS_COV MPRO IN COMPLEX WITH AN INHIBITOR N3
分子名称:3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Yang, H., Xue, X., Yang, K., Zhao, Q., Bartlam, M., Rao, Z.
登録日2005-08-10
公開日2005-09-13
最終更新日2015-12-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
2D2D
  • Download 2d2d
  • View 2d2d
Molmil generated image of 2d2d
CRYSTAL STRUCTURE OF SARS-COV MPRO IN COMPLEX WITH AN INHIBITOR I2
分子名称:3C-like proteinase, ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE
著者Yang, H., Bartlam, M., Xue, X., Yang, K., Liang, W., Ding, Y., Rao, Z.
登録日2005-09-08
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
5GXJ
  • Download 5gxj
  • View 5gxj
Molmil generated image of 5gxj
ZIKA VIRUS NS2B-NS3 PROTEASE
分子名称:FLAVIVIRUS_NS2B,LINKER,Peptidase S7
著者Yang, H., Chen, X., Ji, X., Xiong, Y., Yang, K.
登録日2016-09-18
公開日2017-05-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Viral protease activation mechanism
To Be Published
1XMA
  • Download 1xma
  • View 1xma
Molmil generated image of 1xma
STRUCTURE OF A TRANSCRIPTIONAL REGULATOR FROM CLOSTRIDIUM THERMOCELLUM CTH-833
分子名称:Predicted transcriptional regulator, MERCURY (II) ION, UNKNOWN ATOM OR ION
著者Yang, H., Chen, L., Lee, D., Habel, J., Nguyen, J., Chang, S.-H., Kataeva, I., Xu, H., Chang, J., Zhao, M., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Praissman, J., Zhang, H., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-01
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
3NK6
  • Download 3nk6
  • View 3nk6
Molmil generated image of 3nk6
STRUCTURE OF THE NOSIHEPTIDE-RESISTANCE METHYLTRANSFERASE
分子名称:23S rRNA methyltransferase
著者Yang, H., Wang, Z., Shen, Y., Wang, P., Murchie, A., Xu, Y.
登録日2010-06-18
公開日2010-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
3NK7
  • Download 3nk7
  • View 3nk7
Molmil generated image of 3nk7
STRUCTURE OF THE NOSIHEPTIDE-RESISTANCE METHYLTRANSFERASE S-ADENOSYL-L-METHIONINE COMPLEX
分子名称:23S rRNA methyltransferase, S-ADENOSYLMETHIONINE
著者Yang, H., Wang, Z., Shen, Y., Wang, P., Murchie, A., Xu, Y.
登録日2010-06-18
公開日2010-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
1ZGH
  • Download 1zgh
  • View 1zgh
Molmil generated image of 1zgh
METHIONYL-TRNA FORMYLTRANSFERASE FROM CLOSTRIDIUM THERMOCELLUM
分子名称:Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION
著者Yang, H., Kataeva, I., Xu, H., Zhao, M., Chang, J., Liu, Z., Chen, L., Tempel, W., Habel, J., Zhou, W., Lee, D., Lin, D., Chang, S., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Wang, B., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-04-21
公開日2005-05-03
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Methionyl-tRNA formyltransferase from Clostridium thermocellum
To be published
3NFP
  • Download 3nfp
  • View 3nfp
Molmil generated image of 3nfp
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THERAPEUTIC ANTIBODY DACLIZUMAB IN COMPLEX WITH IL-2RA (CD25) ECTODOMAIN
分子名称:Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha
著者Yang, H., Wang, J., Du, J., Zhong, C., Guo, Y., Ding, J.
登録日2010-06-10
公開日2010-09-15
最終更新日2013-10-16
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis of immunosuppression by the therapeutic antibody daclizumab
Cell Res., 20, 2010
3NFS
  • Download 3nfs
  • View 3nfs
Molmil generated image of 3nfs
CRYSTAL STRUCTURE THE FAB FRAGMENT OF THERAPEUTIC ANTIBODY DACLIZUMAB
分子名称:Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab
著者Yang, H., Wang, J., Du, J., Zhong, C., Guo, Y., Ding, J.
登録日2010-06-10
公開日2010-09-15
最終更新日2013-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of immunosuppression by the therapeutic antibody daclizumab
Cell Res., 20, 2010
3V9R
  • Download 3v9r
  • View 3v9r
Molmil generated image of 3v9r
CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE MHF COMPLEX
分子名称:Uncharacterized protein YOL086W-A, Uncharacterized protein YDL160C-A, SULFATE ION
著者Yang, H., Zhang, T., Zhong, C., Li, H., Zhou, J., Ding, J.
登録日2011-12-28
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Saccharomyces Cerevisiae MHF Complex Structurally Resembles the Histones (H3-H4)(2) Heterotetramer and Functions as a Heterotetramer
Structure, 20, 2012
5H64
  • Download 5h64
  • View 5h64
Molmil generated image of 5h64
CRYO-EM STRUCTURE OF MTORC1
分子名称:Serine/threonine-protein kinase mTOR, Regulatory-associated protein of mTOR, Target of rapamycin complex subunit LST8
著者Yang, H., Wang, J., Liu, M., Chen, X., Huang, M., Tan, D., Dong, M., Wong, C.C.L., Wang, J., Xu, Y., Wang, H.
登録日2016-11-10
公開日2017-01-25
最終更新日2017-12-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
1MIU
  • Download 1miu
  • View 1miu
Molmil generated image of 1miu
STRUCTURE OF A BRCA2-DSS1 COMPLEX
分子名称:Deleted in split hand/split foot protein 1, Breast Cancer type 2 susceptibility protein, MERCURY (II) ION
著者Yang, H., Jeffrey, P.D., Miller, J., Kinnucan, E., Sun, Y., Thoma, N.H., Zheng, N., Chen, P.L., Lee, W.H., Pavletich, N.P.
登録日2002-08-23
公開日2002-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
Science, 297, 2002
1MJE
  • Download 1mje
  • View 1mje
Molmil generated image of 1mje
STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX
分子名称:5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2
著者Yang, H., Jeffrey, P.D., Miller, J., Kinnucan, E., Sun, Y., Thoma, N.H., Zheng, N., Chen, P.L., Lee, W.H., Pavletich, N.P.
登録日2002-08-27
公開日2002-09-27
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
1YEM
  • Download 1yem
  • View 1yem
Molmil generated image of 1yem
CONSERVED HYPOTHETICAL PROTEIN PFU-838710-001 FROM PYROCOCCUS FURIOSUS
分子名称:Conserved hypothetical protein Pfu-838710-001, PLATINUM (II) ION, UNKNOWN ATOM OR ION
著者Yang, H., Chang, J., Shah, A., Ng, J.D., Liu, Z.-J., Chen, L., Lee, D., Tempel, W., Praissman, J.L., Lin, D., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Jenney Jr., F.E., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-28
公開日2005-01-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus
To be published
2IA0
  • Download 2ia0
  • View 2ia0
Molmil generated image of 2ia0
TRANSCRIPTIONAL REGULATORY PROTEIN PF0864 FROM PYROCOCCUS FURIOSUS A MEMBER OF THE ASNC FAMILY (PF0864)
分子名称:Putative HTH-type transcriptional regulator PF0864, GOLD ION
著者Yang, H., Chang, J., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-09-06
公開日2006-10-31
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal Structure of the Transcriptional Regulatory Protein PF0864: an Asnc Family member from Pyrococcus Furiosus
To be Published
2P9J
  • Download 2p9j
  • View 2p9j
Molmil generated image of 2p9j
CRYSTAL STRUCTURE OF AQ2171 FROM AQUIFEX AEOLICUS
分子名称:Hypothetical protein AQ2171
著者Yang, H., Chen, L., Agari, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-26
公開日2007-05-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of AQ2171 from Aquifex aeolicus
To be Published
2QLZ
  • Download 2qlz
  • View 2qlz
Molmil generated image of 2qlz
CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR PF0095 FROM PYROCOCCUS FURIOSUS
分子名称:Transcription Factor PF0095
著者Yang, H., Lipscomb, G.L., Scott, R.A., Rose, J.P., Wang, B.C.
登録日2007-07-13
公開日2008-07-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Transcription Factor PF0095 from Pyrococcus furiosus
To be Published
2QUF
  • Download 2quf
  • View 2quf
Molmil generated image of 2quf
CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR AXXA-PF0095 FROM PYROCOCCUS FURIOSUS
分子名称:Transcription Factor PF0095, GLYCEROL
著者Yang, H., Lipscomb, G.L., Scott, R.A., Rose, J.P., Wang, B.C.
登録日2007-08-05
公開日2008-08-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Transcription Factor AXXA-PF0095 from Pyrococcus furiosus
To be Published