Author results

6JSJ
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STRUCTURAL ANALYSIS OF A TRIMERIC ASSEMBLY OF THE MITOCHONDRIAL DYNAMIN-LIKE GTPASE MGM1
Descriptor:Dynamin-like GTPase MGM1, mitochondrial, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Yan, L., Li, L.
Deposit date:2019-04-08
Release date:2020-02-19
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1.
Proc.Natl.Acad.Sci.USA, 117, 2020
5YEW
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STRUCTURAL BASIS FOR GTP HYDROLYSIS AND CONFORMATIONAL CHANGE OF MITOFUSIN 1 IN MEDIATING MITOCHONDRIAL FUSION
Descriptor:Mitofusin-1,Mitofusin-1 fusion protein, GUANOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Yan, L., Qi, Y., Huang, X., Yu, C.
Deposit date:2017-09-20
Release date:2018-01-31
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion
Nat. Struct. Mol. Biol., 25, 2018
5CA8
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STRUCTURES OF THE YEAST DYNAMIN-LIKE GTPASE SEY1P IN COMPLEX WITH GDP
Descriptor:Protein SEY1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L.
Deposit date:2015-06-29
Release date:2015-09-16
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5CA9
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STRUCTURES OF THE CANDIDA ALBICANS SEY1P GTPASE IN COMPLEX WITH GDPALF4-
Descriptor:Protein SEY1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ...
Authors:Yan, L.
Deposit date:2015-06-29
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5CB2
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THE STRUCTURE OF CANDIDA ALBICANS SEY1P IN COMPLEX WITH GMPPNP
Descriptor:Protein SEY1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Yan, L., Sun, S., Wang, W., Shi, J., Hu, X., Wang, S., Rao, Z., Hu, J., Lou, Z.
Deposit date:2015-06-30
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5GJK
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CRYSTAL STRUCTURE OF BAF47 AND BAF155 COMPLEX
Descriptor:SWI/SNF complex subunit SMARCC1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, GLYCEROL, ...
Authors:Yan, L., Qian, C.
Deposit date:2016-06-30
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Structural Insights into BAF47 and BAF155 Complex Formation.
J. Mol. Biol., 429, 2017
5GNT
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BDLP-LIKE FOLDING OF MITOFUSIN 1
Descriptor:Mitofusin-1, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L., Yu, C., Ming, Z., Rao, Z., Lou, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-11-23
Method:X-RAY DIFFRACTION (2.665 Å)
Cite:the structure of mini-MFN1 in complex with GDP
To Be Published
5YEJ
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CRYSTAL STRUCTURE OF BIOQ WITH ITS NATUREL DOUBLE-STRANDED DNA OPERATOR
Descriptor:TetR family transcriptional regulator, DNA (5'-D(*AP*CP*CP*TP*GP*AP*AP*CP*AP*CP*CP*GP*TP*TP*CP*AP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*TP*GP*AP*AP*CP*GP*GP*TP*GP*TP*TP*CP*AP*GP*GP*T)-3')
Authors:Yan, L., Guan, Z.Y., Zou, T.T.
Deposit date:2017-09-17
Release date:2018-09-26
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway.
Biochim Biophys Acta Gen Subj, 1862, 2018
5YEK
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CRYSTAL STRUCTURE OF BIOQ
Descriptor:TetR family transcriptional regulator
Authors:Yan, L., Guan, Z.Y., Zou, T.T.
Deposit date:2017-09-17
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway.
Biochim Biophys Acta Gen Subj, 1862, 2018
5YVD
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF ENDORIBONUCLEASE NSP15 ENCODED BY MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS
Descriptor:Nsp15, GLYCEROL
Authors:Yan, L., Zhang, L.
Deposit date:2017-11-24
Release date:2018-08-22
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Biochemical Characterization of Endoribonuclease Nsp15 Encoded by Middle East Respiratory Syndrome Coronavirus.
J. Virol., 92, 2018
6JYT
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DELICATE STRUCTURAL COORDINATION OF THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS NSP13 UPON ATP HYDROLYSIS
Descriptor:Helicase, ZINC ION
Authors:Yan, L., Jia, Z.
Deposit date:2019-04-28
Release date:2019-09-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis.
Nucleic Acids Res., 47, 2019
5ZUV
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CRYSTAL STRUCTURE OF THE HUMAN CORONAVIRUS 229E HR1 MOTIF IN COMPLEX WITH PAN-COVS INHIBITOR EK1
Descriptor:Spike glycoprotein,Spike glycoprotein,inhibitor EK1, CHLORIDE ION
Authors:Yan, L., Yang, B., Wilson, I.A.
Deposit date:2018-05-08
Release date:2019-04-10
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5ZVK
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CRYSTAL STRUCTURE OF THE HUMAN CORONAVIRUS MERS HR1 MOTIF IN COMPLEX WITH PAN-COVS INHIBITOR EK1
Descriptor:Human Coronavirus MERS HR1 motif, pan-CoV inhibitory peptide EK1
Authors:Yan, L., Yang, B., Wilson, I.A.
Deposit date:2018-05-11
Release date:2019-04-10
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5ZVM
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CRYSTAL STRUCTURE OF THE HUMAN CORONAVIRUS SARS HR1 MOTIF IN COMPLEX WITH PAN-COVS INHIBITOR EK1
Descriptor:Spike glycoprotein, pan-CoV inhibitory peptide EK1
Authors:Yan, L., Yang, B., Wilson, I.A.
Deposit date:2018-05-11
Release date:2019-04-10
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5JXR
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CRYSTAL STRUCTURE OF MTISWI
Descriptor:Chromatin-remodeling complex ATPase-like protein, CHLORIDE ION
Authors:Chen, Z., Yan, L.
Deposit date:2016-05-13
Release date:2016-12-07
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Structure and regulation of the chromatin remodeller ISWI
Nature, 540, 2016
5JXT
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CRYSTAL STRUCTURE OF MTISWI BOUND WITH HISTONE H4 TAIL
Descriptor:Chromatin-remodeling complex ATPase-like protein, Histone H4
Authors:Chen, Z., Yan, L.
Deposit date:2016-05-13
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Structure and regulation of the chromatin remodeller ISWI
Nature, 540, 2016
5GNR
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THE STRUCTURE OF MINI-MFN1 K88A IN COMPLEX WITH GDP
Descriptor:Mitofusin-1, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L., Yu, C., Ming, Z., Lou, Z., Rao, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-11-23
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:BDLP-like folding of Mitofusin 1
To Be Published
5GNU
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THE STRUCTURE OF MINI-MFN1 APO
Descriptor:Mitofusin-1
Authors:Yan, L., Yu, C., Ming, Z., Lou, Z., Rao, Z., Lou, J.
Deposit date:2016-07-25
Release date:2016-11-23
Method:X-RAY DIFFRACTION (4.113 Å)
Cite:BDLP-like folding of Mitofusin 1
To Be Published
5YL9
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1.86 ANGSTROM CRYSTAL STRUCTURE OF HUMAN CORONAVIRUS 229E FUSION CORE
Descriptor:Spike glycoprotein
Authors:Yang, B., Yan, L., Meng, B., WIlson, I.A.
Deposit date:2017-10-17
Release date:2018-09-26
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 angstrom resolution
Acta Crystallogr D Struct Biol, 74, 2018
6JTG
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STRUCTURAL INSIGHTS INTO G DOMAIN DIMERIZATION AND PATHOGENIC MUTATIONS OF OPA1
Descriptor:Dynamin-like 120 kDa protein, mitochondrial,OPA1 protein, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Yan, L., Hu, J.
Deposit date:2019-04-11
Release date:2020-04-22
Last modified:2020-05-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into G domain dimerization and pathogenic mutation of OPA1.
J.Cell Biol., 219, 2020
4PBU
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SERIAL TIME-RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER THE S1 STATE
Descriptor:Photosystem Q(B) protein 1, Photosystem II core light harvesting protein, Photosystem II CP43 protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R.A., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-04-13
Release date:2014-07-16
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
4RVY
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SERIAL TIME RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER. THE S STATE AFTER TWO FLASHES (S3)
Descriptor:Photosystem II protein D1 1, Photosystem II CP47 reaction center protein, Photosystem II CP43 reaction center protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.-H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-11-29
Release date:2015-11-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
6M71
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SARS-COV-2 RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH COFACTORS
Descriptor:SARS-Cov-2 NSP 12, SARS-Cov-2 NSP 7, SARS-Cov-2 NSP 8
Authors:Gao, Y., Yan, L., Huang, Y., Liu, F., Cao, L., Wang, T., Wang, Q., Lou, Z., Rao, Z.
Deposit date:2020-03-16
Release date:2020-04-01
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Science, 368, 2020
7BTF
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SARS-COV-2 RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH COFACTORS IN REDUCED CONDITION
Descriptor:NSP12, NSP7, NSP8, ...
Authors:Gao, Y., Yan, L., Huang, Y., Liu, F., Cao, L., Wang, T., Wang, Q., Lou, Z., Rao, Z.
Deposit date:2020-04-01
Release date:2020-04-08
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Science, 368, 2020
4X2Z
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STRUCTURAL VIEW AND SUBSTRATE SPECIFICITY OF PAPAIN-LIKE PROTEASE FROM AVIAN INFECTIOUS BRONCHITIS VIRUS
Descriptor:Nonstructural protein 3, ZINC ION
Authors:Kong, L., Shaw, N., Yan, L., Lou, Z., Rao, Z.
Deposit date:2014-11-27
Release date:2015-01-28
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus.
J.Biol.Chem., 290, 2015
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170172
PDB entries from 2020-10-21