Author results

1JQD
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (THR105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND HISTAMINE
Descriptor:Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, HISTAMINE
Authors:Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X.
Deposit date:2001-08-06
Release date:2002-08-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1JQE
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (ILE105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND ANTIMALARIAL DRUG QUINACRINE
Descriptor:Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, QUINACRINE, ...
Authors:Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X.
Deposit date:2001-08-06
Release date:2002-08-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1PY5
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CRYSTAL STRUCTURE OF TGF-BETA RECEPTOR I KINASE WITH INHIBITOR
Descriptor:TGF-beta receptor type I, SULFATE ION, 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE
Authors:Zhang, F., Sawyer, J.S.
Deposit date:2003-07-08
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Bioorg.Med.Chem.Lett., 14, 2004
1RW8
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CRYSTAL STRUCTURE OF TGF-BETA RECEPTOR I KINASE WITH ATP SITE INHIBITOR
Descriptor:TGF-beta receptor type I, 3-(4-FLUOROPHENYL)-2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOLE
Authors:Zhang, F., Sawyer, J.S.
Deposit date:2003-12-16
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
Bioorg.Med.Chem.Lett., 14, 2004
3UIM
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STRUCTURAL BASIS FOR THE IMPACT OF PHOSPHORYLATION ON PLANT RECEPTOR-LIKE KINASE BAK1 ACTIVATION
Descriptor:BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Lou, Z.Y., Yan, L.M., Ma, Y.Y.
Deposit date:2011-11-05
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the impact of phosphorylation on the activation of plant receptor-like kinase BAK1
Cell Res., 22, 2012
4EEV
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CRYSTAL STRUCTURE OF C-MET IN COMPLEX WITH LY2801653
Descriptor:Hepatocyte growth factor receptor, N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
Authors:Wang, Y., Stout, S.L.
Deposit date:2012-03-28
Release date:2013-04-10
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Invest New Drugs, 31, 2013
4GO5
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THE REGULATORY SUBUNIT OF ASPARTATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Aspartokinase
Authors:Yang, Q., Li, X.
Deposit date:2012-08-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
4GO7
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THE REGULATORY SUBUNIT OF ASPARTATE KINASE IN COMPLEX WITH THREONINE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Aspartokinase, THREONINE
Authors:Yang, Q., Li, X.
Deposit date:2012-08-19
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis.
Protein Cell, 2, 2011
4PBU
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SERIAL TIME-RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER THE S1 STATE
Descriptor:Photosystem Q(B) protein 1, Photosystem II core light harvesting protein, Photosystem II CP43 protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R.A., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-04-13
Release date:2014-07-16
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
4RVY
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SERIAL TIME RESOLVED CRYSTALLOGRAPHY OF PHOTOSYSTEM II USING A FEMTOSECOND X-RAY LASER. THE S STATE AFTER TWO FLASHES (S3)
Descriptor:Photosystem II protein D1 1, Photosystem II CP47 reaction center protein, Photosystem II CP43 reaction center protein, ...
Authors:Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K.N., Hunter, M., Shoeman, R.L., White, T.A., Wang, D., James, D., Yang, J.-H., Cobb, D.E., Reeder, B., Sierra, R.G., Liu, H., Barty, A., Aquila, A., Deponte, D., Kirian, R., Bari, S., Bergkamp, J.J., Beyerlein, K., Bogan, M.J., Caleman, C., Chao, T.-C., Conrad, C.E., Davis, K.M., Fleckenstein, H., Galli, L., Hau-Riege, S.P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A.V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T.A., Moore, A.L., Pushkar, Y., Williams, G.J., Boutet, S., Doak, R.B., Weierstall, U., Frank, M., Chapman, H.N., Spence, J.C.H., Fromme, P.
Deposit date:2014-11-29
Release date:2015-11-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Nature, 513, 2014
4X2Z
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STRUCTURAL VIEW AND SUBSTRATE SPECIFICITY OF PAPAIN-LIKE PROTEASE FROM AVIAN INFECTIOUS BRONCHITIS VIRUS
Descriptor:Nonstructural protein 3, ZINC ION
Authors:Kong, L., Shaw, N., Yan, L., Lou, Z., Rao, Z.
Deposit date:2014-11-27
Release date:2015-01-28
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus.
J.Biol.Chem., 290, 2015
5CA8
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STRUCTURES OF THE YEAST DYNAMIN-LIKE GTPASE SEY1P IN COMPLEX WITH GDP
Descriptor:Protein SEY1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L.
Deposit date:2015-06-29
Release date:2015-09-16
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5CA9
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STRUCTURES OF THE CANDIDA ALBICANS SEY1P GTPASE IN COMPLEX WITH GDPALF4-
Descriptor:Protein SEY1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ...
Authors:Yan, L.
Deposit date:2015-06-29
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5CB2
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THE STRUCTURE OF CANDIDA ALBICANS SEY1P IN COMPLEX WITH GMPPNP
Descriptor:Protein SEY1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Yan, L., Sun, S., Wang, W., Shi, J., Hu, X., Wang, S., Rao, Z., Hu, J., Lou, Z.
Deposit date:2015-06-30
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5EVM
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CRYSTAL STRUCTURE OF NIPAH VIRUS FUSION GLYCOPROTEIN IN THE PREFUSION STATE
Descriptor:Fusion glycoprotein F0, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Xu, K., Nikolov, D.B.
Deposit date:2015-11-20
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.367 Å)
Cite:Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.
Plos Pathog., 11, 2015
5GJK
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CRYSTAL STRUCTURE OF BAF47 AND BAF155 COMPLEX
Descriptor:SWI/SNF complex subunit SMARCC1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, GLYCEROL, ...
Authors:Yan, L., Qian, C.
Deposit date:2016-06-30
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Structural Insights into BAF47 and BAF155 Complex Formation.
J. Mol. Biol., 429, 2017
5GNR
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THE STRUCTURE OF MINI-MFN1 K88A IN COMPLEX WITH GDP
Descriptor:Mitofusin-1, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L., Yu, C., Ming, Z., Lou, Z., Rao, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-11-23
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:BDLP-like folding of Mitofusin 1
To Be Published
5GNS
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STRUCTURES OF HUMAN MITOFUSIN 1 PROVIDE INSIGHT INTO MITOCHONDRIAL TETHERING
Descriptor:Mitofusin-1, GUANOSINE-5'-TRIPHOSPHATE
Authors:Qi, Y., Yan, L., Yu, C., Guo, X., Zhou, X., Hu, X., Huang, X., Rao, Z., Lou, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-12-07
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
5GNT
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BDLP-LIKE FOLDING OF MITOFUSIN 1
Descriptor:Mitofusin-1, GUANOSINE-5'-DIPHOSPHATE
Authors:Yan, L., Yu, C., Ming, Z., Rao, Z., Lou, Z., Hu, J.
Deposit date:2016-07-24
Release date:2016-11-23
Method:X-RAY DIFFRACTION (2.665 Å)
Cite:the structure of mini-MFN1 in complex with GDP
To Be Published
5GNU
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THE STRUCTURE OF MINI-MFN1 APO
Descriptor:Mitofusin-1
Authors:Yan, L., Yu, C., Ming, Z., Lou, Z., Rao, Z., Lou, J.
Deposit date:2016-07-25
Release date:2016-11-23
Method:X-RAY DIFFRACTION (4.113 Å)
Cite:BDLP-like folding of Mitofusin 1
To Be Published
5GO3
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CRYSTAL STRUCTURE OF A DI-NUCLEOTIDE CYCLASE VIBRIO MUTANT
Descriptor:Cyclic GMP-AMP synthase
Authors:Ming, Z.H., Wang, W., Xie, Y.C., Chen, Y.C., Yan, L.M., Lou, Z.Y.
Deposit date:2016-07-26
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a di-nucleotide cyclase Vibrio mutant
To Be Published
5HYW
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THE CRYSTAL STRUCTURE OF THE D3-ASK1 COMPLEX
Descriptor:F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A
Authors:Yao, R.F., Ming, Z.H., Yan, L.M., Rao, Z.H., Lou, Z.Y., Xie, D.X.
Deposit date:2016-02-02
Release date:2016-08-03
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
5HZG
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THE CRYSTAL STRUCTURE OF THE STRIGOLACTONE-INDUCED ATD14-D3-ASK1 COMPLEX
Descriptor:Strigolactone esterase D14, F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A, ...
Authors:Yao, R.F., Ming, Z.H., Yan, L.M., Rao, Z.H., Lou, Z.Y., Xie, D.X.
Deposit date:2016-02-02
Release date:2016-08-03
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
5JXR
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CRYSTAL STRUCTURE OF MTISWI
Descriptor:Chromatin-remodeling complex ATPase-like protein, CHLORIDE ION
Authors:Chen, Z., Yan, L.
Deposit date:2016-05-13
Release date:2016-12-07
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Structure and regulation of the chromatin remodeller ISWI
Nature, 540, 2016
5JXT
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CRYSTAL STRUCTURE OF MTISWI BOUND WITH HISTONE H4 TAIL
Descriptor:Chromatin-remodeling complex ATPase-like protein, Histone H4
Authors:Chen, Z., Yan, L.
Deposit date:2016-05-13
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Structure and regulation of the chromatin remodeller ISWI
Nature, 540, 2016
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