5KHU
 
 | | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | Authors: | Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B. | | Deposit date: | 2016-06-15 | | Release date: | 2016-09-07 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
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4J1T
 | | Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit in P2(1) | | Descriptor: | GLYCEROL, NAD(P) transhydrogenase subunit beta, NAD/NADP transhydrogenase alpha subunit 1, ... | | Authors: | Yamaguchi, M, Leung, J, Schurig Briccio, L.A, Gennis, R.B, Stout, C.D. | | Deposit date: | 2013-02-02 | | Release date: | 2014-02-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Crystal structure analysis of Thermus thermophilus transhydrogenase soluble domains
To be Published
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4J16
 | | Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit | | Descriptor: | CHLORIDE ION, GLYCEROL, NAD(P) transhydrogenase subunit beta, ... | | Authors: | Yamaguchi, M, Leung, J, Schurig Briccio, L.A, Gennis, R.B, Stout, C.D. | | Deposit date: | 2013-02-01 | | Release date: | 2014-02-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Crystal structure analysis of Thermus thermophilus transhydrogenase soluble domains
To be Published
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4RG7
 | | Crystal structure of APC3 | | Descriptor: | Cell division cycle protein 27 homolog | | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.25 Å) | | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
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4RG6
 | | Crystal structure of APC3-APC16 complex | | Descriptor: | Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog | | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
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4RG9
 | | Crystal structure of APC3-APC16 complex (Selenomethionine Derivative) | | Descriptor: | Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog | | Authors: | Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A. | | Deposit date: | 2014-09-29 | | Release date: | 2014-12-24 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
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2LPU
 | | Solution structures of KmAtg10 | | Descriptor: | KmAtg10 | | Authors: | Yamaguchi, M, Noda, N.N, Yamamoto, H, Shima, T, Kumeta, H, Kobashigawa, Y, Akada, R, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-02-19 | | Release date: | 2012-08-01 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural insights into atg10-mediated formation of the autophagy-essential atg12-atg5 conjugate
Structure, 20, 2012
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5YEC
 | | Crystal structure of Atg7CTD-Atg8-MgATP complex in form II | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Autophagy-related protein 8, MAGNESIUM ION, ... | | Authors: | Yamaguchi, M, Satoo, K, Noda, N.N. | | Deposit date: | 2017-09-16 | | Release date: | 2018-03-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.147 Å) | | Cite: | Atg7 Activates an Autophagy-Essential Ubiquitin-like Protein Atg8 through Multi-Step Recognition.
J. Mol. Biol., 430, 2018
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3VX7
 | | Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex | | Descriptor: | E1, E2 | | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | | Deposit date: | 2012-09-11 | | Release date: | 2012-11-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat.Struct.Mol.Biol., 19, 2012
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3VX6
 | | Crystal structure of Kluyveromyces marxianus Atg7NTD | | Descriptor: | E1 | | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | | Deposit date: | 2012-09-11 | | Release date: | 2012-11-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Nat.Struct.Mol.Biol., 19, 2012
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3VQI
 | | Crystal structure of Kluyveromyces marxianus Atg5 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Atg5, SULFATE ION | | Authors: | Yamaguchi, M, Noda, N.N, Yamamoto, H, Shima, T, Kumeta, H, Kobashigawa, Y, Akada, R, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-03-24 | | Release date: | 2012-08-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into atg10-mediated formation of the autophagy-essential atg12-atg5 conjugate
Structure, 20, 2012
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5KHR
 | | Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C) | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | Authors: | VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A. | | Deposit date: | 2016-06-15 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
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1L7D
 | | Crystal Structure of R. rubrum Transhydrogenase Domain I without Bound NAD(H) | | Descriptor: | nicotinamide nucleotide Transhydrogenase, subunit alpha 1 | | Authors: | Prasad, G.S, Wahlberg, M, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | Deposit date: | 2002-03-14 | | Release date: | 2002-11-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Crystal Structures of Transhydrogenase Domain I
with and without Bound NADH
Biochemistry, 41, 2002
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4IZH
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4IZI
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2KWC
 | | The NMR structure of the autophagy-related protein Atg8 | | Descriptor: | Autophagy-related protein 8 | | Authors: | Kumeta, H, Watanabe, M, Nakatogawa, H, Yamaguchi, M, Ogura, K, Adachi, W, Fujioka, Y, Noda, N.N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-05-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the autophagy-related protein Atg8
J.Biomol.Nmr, 47, 2010
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1PNQ
 | | Crystal structure of R. rubrum transhydrogenase domain III bound to NADPH | | Descriptor: | NAD(P) transhydrogenase subunit beta, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Sundaresan, V, Yamaguchi, M, Chartron, J, Stout, C.D. | | Deposit date: | 2003-06-12 | | Release date: | 2003-11-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Conformational Change in the NADP(H) Binding Domain of Transhydrogenase Defines Four States
Biochemistry, 42, 2003
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1PNO
 | | Crystal structure of R. rubrum transhydrogenase domain III bound to NADP | | Descriptor: | NAD(P) transhydrogenase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Sundaresan, V, Yamaguchi, M, Chartron, J, Stout, C.D. | | Deposit date: | 2003-06-12 | | Release date: | 2003-11-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conformational Change in the NADP(H) Binding Domain of Transhydrogenase Defines Four States
Biochemistry, 42, 2003
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1D4O
 | | CRYSTAL STRUCTURE OF TRANSHYDROGENASE DOMAIN III AT 1.2 ANGSTROMS RESOLUTION | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP(H) TRANSHYDROGENASE | | Authors: | Prasad, G.S, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | Deposit date: | 1999-10-04 | | Release date: | 2000-01-20 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.21 Å) | | Cite: | Crystal structure of transhydrogenase domain III at 1.2 A resolution.
Nat.Struct.Biol., 6, 1999
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4O9U
 | | Mechanism of transhydrogenase coupling proton translocation and hydride transfer | | Descriptor: | NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta, NAD/NADP transhydrogenase alpha subunit 1, ... | | Authors: | Leung, J.H, Yamaguchi, M, Moeller, A, Schurig-Briccio, L.A, Gennis, R.B, Potter, C.S, Carragher, B, Stout, C.D. | | Deposit date: | 2014-01-02 | | Release date: | 2015-01-28 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (6.926 Å) | | Cite: | Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.
Science, 347, 2015
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4O9P
 | | Crystal structure of Thermus thermophilis transhydrogeanse domain II dimer SeMet derivative | | Descriptor: | NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta | | Authors: | Leung, J.H, Yamaguchi, M, Moeller, A, Schurig-Briccio, L.A, Gennis, R.B, Potter, C.S, Carragher, B, Stout, C.D. | | Deposit date: | 2014-01-02 | | Release date: | 2014-06-11 | | Last modified: | 2015-01-28 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.
Science, 347, 2015
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4O93
 | | Crystal structure of Thermus thermophilis transhydrogeanse domain II dimer | | Descriptor: | MERCURY (II) ION, NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta | | Authors: | Leung, J.H, Yamaguchi, M, Moeller, A, Schurig-Briccio, L.A, Gennis, R.B, Potter, C.S, Carragher, B, Stout, C.D. | | Deposit date: | 2013-12-31 | | Release date: | 2014-12-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.
Science, 347, 2015
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4O9T
 | | Mechanism of transhydrogenase coupling proton translocation and hydride transfer | | Descriptor: | NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta | | Authors: | Leung, J.H, Yamaguchi, M, Moeller, A, Schurig-Briccio, L.A, Gennis, R.B, Potter, C.S, Carragher, B, Stout, C.D. | | Deposit date: | 2014-01-02 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.079 Å) | | Cite: | Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.
Science, 347, 2015
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1XLT
 | | Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex | | Descriptor: | NAD(P) transhydrogenase subunit alpha part 1, NAD(P) transhydrogenase subunit beta, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Sundaresan, V, Chartron, J, Yamaguchi, M, Stout, C.D. | | Deposit date: | 2004-09-30 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Conformational Diversity in NAD(H) and Transhydrogenase Nicotinamide Nucleotide Binding Domains
J.Mol.Biol., 346, 2005
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1L7E
 | | Crystal Structure of R. rubrum Transhydrogenase Domain I with Bound NADH | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, nicotinamide nucleotide Transhydrogenase, subunit alpha 1 | | Authors: | Prasad, G.S, Wahlberg, M, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | Deposit date: | 2002-03-14 | | Release date: | 2002-11-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structures of Transhydrogenase Domain I
with and without Bound NADH
Biochemistry, 41, 2002
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