Author results

3VC8
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CRYSTAL STRUCTURE OF THE C-TERMINAL CYTOPLASMIC DOMAIN OF NON-STRUCTURAL PROTEIN 4 FROM MOUSE HEPATITIS VIRUS A59
分子名称:RNA-directed RNA polymerase
著者Xu, X., Lou, Z., Ma, Y., Chen, X., Yang, Z., Tong, X., Zhao, Q., Xu, Y., Deng, H., Bartlam, M., Rao, Z.
登録日2012-01-03
公開日2012-01-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
3VCB
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C425S MUTANT OF THE C-TERMINAL CYTOPLASMIC DOMAIN OF NON-STRUCTURAL PROTEIN 4 FROM MOUSE HEPATITIS VIRUS A59
分子名称:RNA-directed RNA polymerase
著者Xu, X., Lou, Z., Ma, Y., Chen, X., Yang, Z., Tong, X., Zhao, Q., Xu, Y., Deng, H., Bartlam, M., Rao, Z.
登録日2012-01-03
公開日2012-01-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
4OIV
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STRUCTURAL BASIS FOR SMALL MOLECULE NDB AS A SELECTIVE ANTAGONIST OF FXR
分子名称:Bile acid receptor, N-benzyl-N-(3-tert-butyl-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino)benzamide
著者Xu, X., Chen, L., Hu, L., Shen, X.
登録日2014-01-20
公開日2015-03-25
最終更新日2015-08-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
J.Biol.Chem., 290, 2015
3B7E
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NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN IN COMPLEX WITH ZANAMIVIR
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
著者Xu, X., Zhu, X., Wilson, I.A.
登録日2007-10-30
公開日2008-10-07
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
3BEQ
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NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
著者Xu, X., Zhu, X., Wilson, I.A.
登録日2007-11-19
公開日2008-09-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
1T09
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX NADP
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Xu, X., Zhao, J., Peng, B., Huang, Q., Arnold, E., Ding, J.
登録日2004-04-08
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
1T0L
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP, ISOCITRATE, AND CALCIUM(2+)
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Xu, X., Zhao, J., Peng, B., Huang, Q., Arnold, E., Ding, J.
登録日2004-04-10
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
2GTH
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CRYSTAL STRUCTURE OF THE WILDTYPE MHV CORONAVIRUS NON-STRUCTURAL PROTEIN NSP15
分子名称:Replicase polyprotein 1ab
著者Xu, X., Zhai, Y., Sun, F., Lou, Z., Su, D., Rao, Z.
登録日2006-04-28
公開日2006-08-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
2GTI
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MUTATION OF MHV CORONAVIRUS NON-STRUCTURAL PROTEIN NSP15 (F307L)
分子名称:Replicase polyprotein 1ab, SULFATE ION, GLYCEROL
著者Xu, X., Zhai, Y., Sun, F., Lou, Z., Su, D., Rao, Z.
登録日2006-04-28
公開日2006-08-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
J.Virol., 80, 2006
3W8H
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CRYSTAL STRUCTURE OF CCM3 IN COMPLEX WITH THE C-TERMINAL REGULATORY DOMAIN OF STK25
分子名称:Programmed cell death protein 10, Serine/threonine-protein kinase 25, SULFATE ION
著者Xu, X., Wang, D.C., Ding, J.
登録日2013-03-13
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
3W8I
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CRYSTAL STRUCTURE OF CCM3 IN COMPLEX WITH THE C-TERMINAL REGULATORY DOMAIN OF MST4
分子名称:Programmed cell death protein 10, Serine/threonine-protein kinase MST4
著者Xu, X., Wang, D.C., Ding, J.
登録日2013-03-13
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
4HBN
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CRYSTAL STRUCTURE OF THE HUMAN HCN4 CHANNEL C-TERMINUS CARRYING THE S672R MUTATION
分子名称:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION
著者Xu, X., Marni, F., Wu, X., Su, Z., Musayev, F., Shrestha, S., Xie, C., Gao, W., Liu, Q., Zhou, L.
登録日2012-09-28
公開日2013-01-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
5UJI
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CRYSTAL STRUCTURE OF HUMAN T2-TRYPTOPHANYL-TRNA SYNTHETASE WITH H130R MUTATION
分子名称:Tryptophan--tRNA ligase, cytoplasmic
著者Xu, X., Yang, X.-L.
登録日2017-01-18
公開日2018-01-17
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.
RNA Biol, 15, 2018
5UJJ
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CRYSTAL STRUCTURE OF HUMAN H130R TRYPTOPHANYL-TRNA SYNTHETASE IN COMPLEX WITH TRPAMP
分子名称:Tryptophan--tRNA ligase, cytoplasmic, TRYPTOPHANYL-5'AMP, ...
著者Xu, X., Yang, X.-L.
登録日2017-01-18
公開日2018-01-17
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.
RNA Biol, 15, 2018
1PCW
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AQUIFEX AEOLICUS KDO8PS IN COMPLEX WITH CADMIUM AND APP, A BISUBSTRATE INHIBITOR
分子名称:2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, 1-DEOXY-6-O-PHOSPHONO-1-[(PHOSPHONOMETHYL)AMINO]-L-THREO-HEXITOL
著者Xu, X., Wang, J., Grison, C., Petek, S., Coutrot, P., Birck, M., Woodard, R.W., Gatti, D.L.
登録日2003-05-17
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase.
Drug DES.DISCOVERY, 18, 2003
1TER
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SOLUTION STRUCTURE OF TERTIAPIN DETERMINED USING NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY
分子名称:TERTIAPIN
著者Xu, X., Nelson, J.W.
登録日1994-04-08
公開日1995-02-07
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of tertiapin determined using nuclear magnetic resonance and distance geometry.
Proteins, 17, 1993
1ZHA
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A. AEOLICUS KDO8PS R106G MUTANT IN COMPLEX WITH PEP AND R5P
分子名称:2-dehydro-3-deoxyphosphooctonate aldolase, RIBOSE-5-PHOSPHATE, CADMIUM ION, ...
著者Xu, X., Kona, F., Wang, J., Lu, J., Stemmler, T., Gatti, D.L.
登録日2005-04-25
公開日2005-09-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop.
Biochemistry, 44, 2005
1ZJI
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AQUIFEX AEOLICUS KDO8PS R106G MUTANT IN COMPLEX WITH 2PGA AND R5P
分子名称:2-dehydro-3-deoxyphosphooctonate aldolase, RIBOSE-5-PHOSPHATE, CADMIUM ION, ...
著者Xu, X., Kona, F., Wang, J., Lu, J., Stemmler, T., Gatti, D.L.
登録日2005-04-28
公開日2005-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Catalytic and Conformational Cycle of Aquifex aeolicus KDO8P Synthase: Role of the L7 Loop
Biochemistry, 44, 2005
2JQR
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SOLUTION MODEL OF CROSSLINKED COMPLEX OF CYTOCHROME C AND ADRENODOXIN
分子名称:Cytochrome c iso-1, Adrenodoxin, mitochondrial, ...
著者Xu, X., Reinle, W., Hannemann, F., Konarev, P.V., Svergun, D.I., Bernhardt, R., Ubbink, M.
登録日2007-06-07
公開日2008-04-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy
J.Am.Chem.Soc., 130, 2008
2KAJ
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NMR STRUCTURE OF GALLIUM SUBSTITUTED FERREDOXIN
分子名称:Ferredoxin-1, GALLIUM (III) ION
著者Xu, X., Ubbink, M., Knaff, D.B.
登録日2008-11-06
公開日2009-11-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of the ga-substituted ferredoxin from Synechocystis sp. PCC6803, a mimic of the native protein.
Biochemistry, 49, 2010
2LY9
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SOLUTION NMR STRUCTURE OF HOMEOBOX 2 DOMAIN FROM HUMAN ZHX1 REPRESSOR, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR7907F
分子名称:Zinc fingers and homeoboxes protein 1
著者Xu, X., Eletsky, A., Mills, J.L., Pulavarti, S.V.S.R.K., Lee, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2012-09-14
公開日2012-11-14
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F
To be Published
2M0C
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SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN OF HUMAN ALX4, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4490C
分子名称:Homeobox protein aristaless-like 4
著者Xu, X., Eletsky, A., Pulavarti, S., Lee, D., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2012-10-24
公開日2012-11-21
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
To be Published
2M9W
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SOLUTION NMR STRUCTURE OF TRANSCRIPTION FACTOR GATA-4 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR4783B
分子名称:Transcription factor GATA-4, ZINC ION
著者Xu, X., Eletsky, A., Lee, D., Kohn, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2013-06-20
公開日2013-07-10
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of a Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B
To be Published
2M9X
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SOLUTION NMR STRUCTURE OF MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 1 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR9151A
分子名称:Microtubule-associated serine/threonine-protein kinase 1
著者Xu, X., Eletsky, A., Shastry, R., Lee, D., Hamilton, K., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2013-06-20
公開日2013-07-10
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Microtubule-associated serine/threonine-protein kinase 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9151A
To be Published
2MIO
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SOLUTION NMR STRUCTURE OF SH3 DOMAIN 1 OF RHO GTPASE-ACTIVATING PROTEIN 10 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR9129A
分子名称:Rho GTPase-activating protein 10
著者Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.K., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2013-12-16
公開日2014-01-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A
To be Published