Author results

1XHO
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CHORISMATE MUTASE FROM CLOSTRIDIUM THERMOCELLUM CTH-682
Descriptor:Chorismate mutase, UNKNOWN ATOM OR ION
Authors:Xu, H., Chen, L., Lee, D., Habel, J.E., Nguyen, J., Chang, S.-H., Kataeva, I., Chang, J., Zhao, M., Yang, H., Horanyi, P., Florence, Q., Tempel, W., Zhou, W., Lin, D., Zhang, H., Praissman, J., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-20
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Away from the edge II: in-house Se-SAS phasing with chromium radiation.
Acta Crystallogr.,Sect.D, 61, 2005
3J6C
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CRYO-EM STRUCTURE OF MAVS CARD FILAMENT
Descriptor:Mitochondrial antiviral-signaling protein
Authors:Xu, H., He, X., Zheng, H., Huang, L.J., Hou, F., Yu, Z., de la Cruz, M.J., Borkowski, B., Zhang, X., Chen, Z.J., Jiang, Q.-X.
Deposit date:2014-02-04
Release date:2014-03-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Structural basis for the prion-like MAVS filaments in antiviral innate immunity.
Elife, 3, 2014
5OCV
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A RARE LYSOZYME CRYSTAL FORM SOLVED USING HIGH-REDUNDANCY 3D ELECTRON DIFFRACTION DATA FROM MICRON-SIZED NEEDLE SHAPED CRYSTALS
Descriptor:Lysozyme C, SODIUM ION
Authors:Xu, H., Lebrette, H., Yang, T., Srinivas, V., Hovmoller, S., Hogbom, M., Zou, X.
Deposit date:2017-07-03
Release date:2018-03-28
Last modified:2018-04-11
Method:ELECTRON CRYSTALLOGRAPHY (2.2 Å)
Cite:A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals.
Structure, 26, 2018
6QRZ
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CRYSTAL STRUCTURE OF R2-LIKE LIGAND-BINDING OXIDASE FROM SULFOLOBUS ACIDOCALDARIUS SOLVED BY 3D MICRO-CRYSTAL ELECTRON DIFFRACTION
Descriptor:Ribonucleoside-diphosphate reductase, MANGANESE (III) ION, FE (III) ION
Authors:Xu, H., Lebrette, H., Clabbers, M.T.B., Zhao, J., Griese, J.J., Zou, X., Hogbom, M.
Deposit date:2019-02-20
Release date:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (3 Å)
Cite:Solving the first novel protein structure by 3D micro-crystal electron diffraction
Biorxiv, 2019
1NLF
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CRYSTAL STRUCTURE OF DNA HELICASE REPA IN COMPLEX WITH SULFATE AT 1.95 A RESOLUTION
Descriptor:Regulatory protein repA, SULFATE ION
Authors:Xu, H., Strater, N., Schroeder, W., Bottcher, C., Ludwig, K., Saenger, W.
Deposit date:2003-01-07
Release date:2003-04-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of DNA helicase RepA in complex with sulfate at 1.95 A resolution implicates structural changes to an "open" form.
Acta Crystallogr.,Sect.D, 59, 2003
1ZGG
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SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE FROM BACILLUS SUBTILIS
Descriptor:Putative low molecular weight protein-tyrosine-phosphatase ywlE
Authors:Xu, H., Xia, B., Jin, C.
Deposit date:2005-04-21
Release date:2006-03-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a low-molecular-weight protein tyrosine phosphatase from Bacillus subtilis
J.Bacteriol., 188, 2006
1ZYZ
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STRUCTURES OF YEAST RIBONUCLOETIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, GLYCINE
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-13
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZZD
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-13
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVU
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVX
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ZLF
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THE STRUCTURAL BASIS FOR PEPTIDOMIMETIC INHIBITION OF EUKARYOTIC RIBONUCLEOTIDE REDUCTASE
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, FTLDADF
Authors:Xu, H., Fairman, J.W., Wijerathna, S.R., LaMacchia, J., Kreischer, N.R., Helmbrecht, E., Cooperman, B.S., Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
2ZLG
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THE STRUCTUAL BASIS FOR PEPTIDOMIMETIC INHIBITION OF EUKARYOTIC RIBONUCLEOTIDE REDUCTASE
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL
Authors:Xu, H., Fairman, J.W., Wijerathna, S.R., LaMacchia, J., Kreischer, N.R., Helmbrecht, E., Cooperman, B.S., Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
6N4I
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STRUCTURAL BASIS OF NAV1.7 INHIBITION BY A GATING-MODIFIER SPIDER TOXIN
Descriptor:Nav1.7 VSD2-NavAb channel chimera protein, Beta/omega-theraphotoxin-Tp2a, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
Authors:Xu, H., Koth, C.M., Payandeh, J.
Deposit date:2018-11-19
Release date:2019-01-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.541 Å)
Cite:Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
6N4Q
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CRYOEM STRUCTURE OF NAV1.7 VSD2 (ACTIVED STATE) IN COMPLEX WITH THE GATING MODIFIER TOXIN PROTX2
Descriptor:Nav1.7 VSD2-NavAb chimera, Beta/omega-theraphotoxin-Tp2a, Fab light chain, ...
Authors:Xu, H., Rohou, A., Arthur, C.P., Estevez, A., Ciferri, C., Payandeh, J., Koth, C.M.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
6N4R
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CRYOEM STRUCTURE OF NAV1.7 VSD2 (DEACTIVED STATE) IN COMPLEX WITH THE GATING MODIFIER TOXIN PROTX2
Descriptor:Nav1.7 VSD2-NavAb chimera, Beta/omega-theraphotoxin-Tp2a, Fab light chain, ...
Authors:Xu, H., Rohou, A., Arthur, C.P., Estevez, A., Ciferri, C., Payandeh, J., Koth, C.M.
Deposit date:2018-11-20
Release date:2019-01-23
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
3F5O
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CRYSTAL STRUCTURE OF HTHEM2(UNDECAN-2-ONE-COA) COMPLEX
Descriptor:Thioesterase superfamily member 2, CHLORIDE ION, undecan-2-one, ...
Authors:Xu, H., Gong, W.
Deposit date:2008-11-04
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis
Biochemistry, 48, 2009
5CQR
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DIMERIZATION OF ELP1 IS ESSENTIAL FOR ELONGATOR COMPLEX ASSEMBLY
Descriptor:Elongator complex protein 1
Authors:Lin, Z., Xu, H., Li, F., Diao, W., Long, J., Shen, Y.
Deposit date:2015-07-22
Release date:2015-08-19
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (3.015 Å)
Cite:Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CQS
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DIMERIZATION OF ELP1 IS ESSENTIAL FOR ELONGATOR COMPLEX ASSEMBLY
Descriptor:Elongator complex protein 1
Authors:Lin, Z., Xu, H., Li, F., Diao, W., Long, J., Shen, Y.
Deposit date:2015-07-22
Release date:2015-08-19
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
2EUD
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I COMPLEXED WITH LIGANDS AND SUBUNIT PEPTIDES
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Dealwis, C., Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J.
Deposit date:2005-10-28
Release date:2006-03-07
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GZY
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SOLUTION STRUCTURES OF THE REDUCED FORM OF THIOREDOXIN FROM BACILLUS SUBTILIS
Descriptor:Thioredoxin
Authors:Xu, H., Zhang, X., Chen, J., Jin, C.
Deposit date:2006-05-12
Release date:2007-02-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J.Biol.Chem., 282, 2007