Author results

1SJ6
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NMR STRUCTURE AND REGULATED EXPRESSION IN APL CELL OF HUMAN SH3BGRL3
Descriptor:SH3 domain-binding glutamic acid-rich-like protein 3
Authors:Xu, C., Tang, Y., Xu, Y., Wu, J., Shi, Y., Zhang, Q., Zheng, P., Du, Y.
Deposit date:2004-03-03
Release date:2005-03-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure and regulated expression in APL cell of human SH3BGRL3.
Febs Lett., 579, 2005
1XWN
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SOLUTION STRUCTURE OF CYCLOPHILIN LIKE 1(PPIL1) AND INSIGHTS INTO ITS INTERACTION WITH SKIP
Descriptor:Peptidyl-prolyl cis-trans isomerase like 1
Authors:Xu, C., Xu, Y., Tang, Y., Wu, J., Shi, Y., Huang, Q., Zhang, Q.
Deposit date:2004-11-01
Release date:2005-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human peptidyl prolyl isomerase like protein 1 and insights into its interaction with SKIP
J.Biol.Chem., 281, 2006
3JPX
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EED: A NOVEL HISTONE TRIMETHYLLYSINE BINDER WITHIN THE EED-EZH2 POLYCOMB COMPLEX
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-04
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZG
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STRUCTURE OF EED IN COMPLEX WITH H3K27ME3
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZH
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EED-H3K79ME3
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3QMG
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*AP*CP*GP*GP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*CP*CP*GP*TP*TP*GP*GP*C)-3', ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMH
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS (DNA-TCGA) BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', ZINC ION
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMI
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS (DNA-ACGT) BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3', ZINC ION, ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3UZD
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CRYSTAL STRUCTURE OF 14-3-3 GAMMA
Descriptor:14-3-3 protein gamma, Histone deacetylase 4, NITRATE ION, ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3JZN
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STRUCTURE OF EED IN APO FORM
Descriptor:Polycomb protein EED
Authors:Xu, C., Bian, C.B., Ouyang, H., Qiu, W., MacKenzie, F., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
4HBD
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CRYSTAL STRUCTURE OF KANK2 ANKYRIN REPEATS
Descriptor:KN motif and ankyrin repeat domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., Cerovina, T., El Bakkouri, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-09-27
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of KANK2 ankyrin repeats
To be Published
4LG7
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CRYSTAL STRUCTURE MBD4 MBD DOMAIN IN COMPLEX WITH METHYLATED CPG DNA
Descriptor:Methyl-CpG-binding domain protein 4, DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., Wernimont, A.K., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2013-06-27
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure MBD4 MBD domain in complex with methylated CpG DNA
To be Published
4LG9
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CRYSTAL STRUCTURE OF TBL1XR1 WD40 REPEATS
Descriptor:F-box-like/WD repeat-containing protein TBL1XR1, UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., He, H., Wu, X., Seitova, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2013-06-27
Release date:2014-04-16
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of TBL1XR1 WD40 repeats
TO BE PUBLISHED
4PXW
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CRYSTAL STRUCTURE OF HUMAN DCAF1 WD40 REPEATS (Q1250L)
Descriptor:Protein VPRBP, UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., He, H., Li, Y., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2014-03-25
Release date:2014-04-16
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of human DCAF1 WD40 repeats (Q1250L)
TO BE PUBLISHED
4R3H
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THE CRYSTAL STRUCTURE OF AN APO RNA BINDING PROTEIN
Descriptor:YTH domain-containing protein 1, UNKNOWN ATOM OR ION, SULFATE ION
Authors:Xu, C., Liu, K., Tempel, W., Li, Y., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2014-08-15
Release date:2014-09-17
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Nat.Chem.Biol., 10, 2014
1KJU
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CA2+-ATPASE IN THE E2 STATE
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1a
Authors:Xu, C., Rice, W.J., He, W., Stokes, D.L.
Deposit date:2001-12-05
Release date:2001-12-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:A structural model for the catalytic cycle of Ca(2+)-ATPase.
J.Mol.Biol., 316, 2002
3SO8
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CRYSTAL STRUCTURE OF ANKRA
Descriptor:Ankyrin repeat family A protein 2
Authors:Xu, C., Bochkarev, A., Bian, C.B., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-06-30
Release date:2011-10-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
4I79
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CRYSTAL STRUCTURE OF HUMAN NUP43
Descriptor:Nucleoporin Nup43, floating chain, unknown sequence, ...
Authors:Xu, C., Tempel, W., Li, Z., He, H., Wernimont, A.K., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-11-30
Release date:2013-02-27
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of human nuclear pore complex component NUP43.
Febs Lett., 589, 2015
4RCI
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CRYSTAL STRUCTURE OF YTHDF1 YTH DOMAIN
Descriptor:YTH domain-containing family protein 1, UNKNOWN ATOM OR ION
Authors:Xu, C., Tempel, W., Liu, K., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2014-09-16
Release date:2014-10-01
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
5GXH
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THE STRUCTURE OF THE GEMIN5 WD40 DOMAIN WITH AAUUUUUG
Descriptor:Gem-associated protein 5, RNA (5'-R(*A*AP*UP*UP*UP*UP*UP*G)-3'), UNKNOWN ATOM OR ION, ...
Authors:Xu, C., He, H., Li, Y., Dong, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-09-17
Release date:2016-10-26
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
Genes Dev., 30, 2016
5GXI
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STRUCUTRE OF THE GEMIN5 WD40 DOMAIN IN COMPLEX WITH AAUUUUUGAG
Descriptor:Gem-associated protein 5, RNA (5'-R(*A*AP*UP*UP*UP*UP*UP*GP*AP*G)-3'), UNKNOWN ATOM OR ION
Authors:Xu, C., He, H., Li, Y., Dong, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2016-09-18
Release date:2016-10-26
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
Genes Dev., 30, 2016
2K2W
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SECOND BRCT DOMAIN OF NBS1
Descriptor:Recombination and DNA repair protein
Authors:Xu, C., Cui, G., Botuyan, M., Mer, G.
Deposit date:2008-04-14
Release date:2008-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.
J.Mol.Biol., 381, 2008
2K4F
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MOUSE CD3EPSILON CYTOPLASMIC TAIL
Descriptor:T-cell surface glycoprotein CD3 epsilon chain
Authors:Xu, C., Call, M.E., Schwieters, C.D., Schnell, J.R., Gagnon, E.E., Wucherpfennig, K.W., Chou, J.J.
Deposit date:2008-06-07
Release date:2008-12-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif.
Cell(Cambridge,Mass.), 135, 2008
4PKM
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CRYSTAL STRUCTURE OF BACILLUS THURINGIENSIS CRY51AA1 PROTOXIN AT 1.65 ANGSTROMS RESOLUTION
Descriptor:Cry51Aa1, GLYCEROL, SULFATE ION, ...
Authors:Xu, C., Chinte, U., Chen, L., Yao, Q., Zhou, D., Meng, Y., Li, L., Rose, J., Bi, L.J., Yu, Z., Sun, M., Wang, B.C.
Deposit date:2014-05-15
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Cry51Aa1: A potential novel insecticidal aerolysin-type beta-pore-forming toxin from Bacillus thuringiensis.
Biochem.Biophys.Res.Commun., 462, 2015
5VX7
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SOLUTION NMR STRUCTURE OF THE BRCT DOMAIN OF S. CEREVISIAE REV1
Descriptor:DNA repair protein REV1
Authors:Xu, C., Cui, G., Botuyan, M.V., Mer, G.
Deposit date:2017-05-23
Release date:2018-01-31
Method:SOLUTION NMR
Cite:Solution NMR structure of the BRCT domain of S. cerevisiae Rev1
To Be Published