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4LAK
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN APO FORM
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Li, W., Zhu, J., Wang, R., Li, Z., Xu, G.L., Ding, J.
Deposit date:2013-06-20
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HJW
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CRYSTAL STRUCTURE OF METARHIZIUM ANISOPLIAE IDCASE IN APO FORM
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-14
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK5
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN APO FORM
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK6
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH 5-NITRO-URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, 5-nitrouracil
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK7
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, URACIL
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAL
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323A MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ...
Authors:Xu, S., Li, W., Zhu, J., Ding, J.
Deposit date:2013-06-20
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAM
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ...
Authors:Xu, S., Li, W., Zhu, J., Ding, J.
Deposit date:2013-06-20
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAN
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Li, W., Zhu, J., Ding, J.
Deposit date:2013-06-20
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4LAO
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT (ZN)
Descriptor:Cordyceps militaris IDCase, ZINC ION, DI(HYDROXYETHYL)ETHER
Authors:Xu, S., Li, W., Zhu, J., Ding, J.
Deposit date:2013-06-20
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
1M8T
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STRUCTURE OF AN ACIDIC PHOSPHOLIPASE A2 FROM THE VENOM OF OPHIOPHAGUS HANNAH AT 2.1 RESOLUTION FROM A HEMIHEDRALLY TWINNED CRYSTAL FORM
Descriptor:Phospholipase a2, CALCIUM ION, HEXANE-1,6-DIOL
Authors:Xu, S., Gu, L., Wang, Q., Shu, Y., Lin, Z.
Deposit date:2002-07-26
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a king cobra phospholipase A2 determined from a hemihedrally twinned crystal.
Acta Crystallogr.,Sect.D, 59, 2003
4M10
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CRYSTAL STRUCTURE OF MURINE CYCLOOXYGENASE-2 COMPLEX WITH ISOXICAM
Descriptor:Prostaglandin G/H synthase 2, N-ACETYL-D-GLUCOSAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Xu, S., Hermanson, D.J., Banerjee, S., Ghebreelasie, K., Marnett, L.J.
Deposit date:2013-08-02
Release date:2014-01-22
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network.
J.Biol.Chem., 289, 2014
4M11
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CRYSTAL STRUCTURE OF MURINE CYCLOOXYGENASE-2 COMPLEX WITH MELOXICAM
Descriptor:Prostaglandin G/H synthase 2, N-ACETYL-D-GLUCOSAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Xu, S., Banerjee, S., Hermanson, D.J., Marnett, L.J.
Deposit date:2013-08-02
Release date:2014-01-22
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network.
J.Biol.Chem., 289, 2014
4O1Z
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CRYSTAL STRUCTURE OF OVINE CYCLOOXYGENASE-1 COMPLEX WITH MELOXICAM
Descriptor:Prostaglandin G/H synthase 1, PROTOPORPHYRIN IX CONTAINING FE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xu, S., Hermanson, D.J., Banerjee, S., Ghebreselasie, K., Clayton, G.M., Garavito, R.M., Marnett, L.J.
Deposit date:2013-12-16
Release date:2014-01-22
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network.
J.Biol.Chem., 289, 2014
4X9Z
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DIMERIC CONOTOXIN ALPHAD-GEXXA
Descriptor:alphaD-conotoxin GeXXA from the venom of Conus generalis
Authors:Xu, S., Zhang, T., Kompella, S., Adams, D., Ding, J., Wang, C.
Deposit date:2014-12-12
Release date:2015-12-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
Sci Rep, 5, 2015
5VP7
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CRYSTAL STRUCTURE OF HUMAN KRAS G12A MUTANT IN COMPLEX WITH GDP
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, S., Long, B., Boris, G., Chen, A., Ni, S., Kennedy, M.A.
Deposit date:2017-05-04
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VPI
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CRYSTAL STRUCTURE OF HUMAN KRAS G12A MUTANT IN COMPLEX WITH GTP
Descriptor:GTPase KRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-05
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VPY
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CRYSTAL STRUCTURE OF HUMAN KRAS G12A MUTANT IN COMPLEX WITH GPPNHP
Descriptor:GTPase KRas, MAGNESIUM ION, 2-amino-9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-alpha-L-xylofuranosyl}-1,9-dihydro-6H-purin-6-one, ...
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VPZ
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CRYSTAL STRUCTURE OF HUMAN KRAS G12A MUTANT IN COMPLEX WITH GTP-GAMMA-S
Descriptor:GTPase KRas, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VQ0
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CRYSTAL STRUCTURE OF HUMAN KRAS G12A MUTANT IN COMPLEX WITH GDP (EDTA SOAKED)
Descriptor:GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VQ1
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CRYSTAL STRUCTURE OF HUMAN KRAS Q61A MUTANT IN COMPLEX WITH GDP
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-07
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VQ2
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CRYSTAL STRUCTURE OF HUMAN WT-KRAS IN COMPLEX WITH GTP
Descriptor:GTPase KRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-07
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VQ6
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CRYSTAL STRUCTURE OF HUMAN WT-KRAS IN COMPLEX WITH GTP-GAMMA-S
Descriptor:GTPase KRas, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-08
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5VQ8
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CRYSTAL STRUCTURE OF HUMAN WT-KRAS IN COMPLEX WITH GDP (EDTA SOAKED)
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-05-08
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
5W22
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CRYSTAL STRUCTURE OF HUMAN WT-KRAS IN COMPLEX WITH GDP
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Xu, S., Long, B., Boris, G., Ni, S., Kennedy, M.A.
Deposit date:2017-06-05
Release date:2017-12-06
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73, 2017
6BL3
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CRYSTAL COMPLEX OF CYCLOOXYGENASE-2 WITH INDOMETHACIN-BUTYLDIAMINE-DANSYL CONJUGATE
Descriptor:Prostaglandin G/H synthase 2, N-ACETYL-D-GLUCOSAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Xu, S., Uddin, M.J., Banerjee, S., Marnett, L.J.
Deposit date:2017-11-09
Release date:2018-11-14
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.217 Å)
Cite:Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site.
J.Biol.Chem., 294, 2019