Author results

6INE
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CRYSTAL STRUCTURE OF HUMAN ASH1L-MRG15 COMPLEX
Descriptor:Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ZINC ION, ...
Authors:Hou, P., Huang, C., Liu, C.P., Yu, T., Yin, Y., Zhu, B., Xu, R.M.
Deposit date:2018-10-25
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 2019
5ZB9
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CRYSTAL STRUCTURE OF RTT109 FROM ASPERGILLUS FUMIGATUS
Descriptor:DNA damage response protein Rtt109, putative, GLYCEROL
Authors:Zhang, L., Serra-Cardona, A., Zhou, H., Wang, M., Yang, N., Zhang, Z., Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5ZBA
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CRYSTAL STRUCTURE OF RTT109-ASF1-H3-H4-COA COMPLEX
Descriptor:DNA damage response protein Rtt109, putative, Histone chaperone asf1, ...
Authors:Zhang, L., Serra-Cardona, A., Zhou, H., Wang, M., Yang, N., Zhang, Z., Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5ZBB
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CRYSTAL STRUCTURE OF RTT109-ASF1-H3-H4 COMPLEX
Descriptor:DNA damage response protein Rtt109, putative, Histone chaperone asf1, ...
Authors:Zhang, L., Serra-Cardona, A., Zhou, H., Wang, M., Yang, N., Zhang, Z., Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5H1J
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5
Descriptor:Gem-associated protein 5
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1K
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH 13-NT U4 SNRNA FRAGMENT
Descriptor:Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3')
Authors:Wang, Y., Jin, W., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1L
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH 7-NT U4 SNRNA FRAGMENT
Descriptor:Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3'), GLYCEROL
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1M
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH M7G
Descriptor:Gem-associated protein 5, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5EX0
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CRYSTAL STRUCTURE OF HUMAN SMYD3 IN COMPLEX WITH A MAP3K2 PEPTIDE
Descriptor:Histone-lysine N-methyltransferase SMYD3, MAP3K2 peptide, ZINC ION, ...
Authors:Fu, W., Liu, N., Qiao, Q., Wang, M., Min, J., Zhu, B., Xu, R.M., Yang, N.
Deposit date:2015-11-23
Release date:2016-03-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
J.Biol.Chem., 291, 2016
5EX3
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CRYSTAL STRUCTURE OF HUMAN SMYD3 IN COMPLEX WITH A VEGFR1 PEPTIDE
Descriptor:Histone-lysine N-methyltransferase SMYD3, VEGFR1 peptide, ZINC ION, ...
Authors:Qiao, Q., Fu, W., Liu, N., Wang, M., Min, J., Zhu, B., Xu, R.M., Yang, N.
Deposit date:2015-11-23
Release date:2016-03-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.408 Å)
Cite:Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
J.Biol.Chem., 291, 2016
5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:DNA (146-MER), Histone H3.2, Histone H4, ...
Authors:Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
5EX7
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CRYSTAL STRUCTURE OF BRAT NHL DOMAIN IN COMPLEX WITH AN 8-NT HUNCHBACK MRNA
Descriptor:Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3')
Authors:Wang, Y., Yu, Z., Wang, M., Liu, C.P., Yang, N., Xu, R.M.
Deposit date:2015-11-23
Release date:2015-12-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
5CQQ
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CRYSTAL STRUCTURE OF THE DROSOPHILA ZESTE DNA BINDING DOMAIN IN COMPLEX WITH DNA
Descriptor:Regulatory protein zeste, DNA (5'-D(*CP*TP*GP*TP*TP*TP*TP*CP*CP*AP*CP*TP*CP*GP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*CP*GP*AP*GP*TP*GP*GP*AP*AP*AP*AP*CP*AP*G)-3')
Authors:Gao, G.N., Wang, M., Yang, N., Huang, Y., Xu, R.M.
Deposit date:2015-07-22
Release date:2015-11-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of Zeste-DNA Complex Reveals a New Modality of DNA Recognition by Homeodomain-Like Proteins
J.Mol.Biol., 427, 2015
5CD7
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CRYSTAL STRUCTURE OF THE NTD L199M OF DROSOPHILA OSKAR PROTEIN
Descriptor:Maternal effect protein oskar, GLYCEROL
Authors:Yang, N., Hu, M., Yu, Z., Wang, M., Lehmann, R., Xu, R.M.
Deposit date:2015-07-03
Release date:2015-09-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
5CD8
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CRYSTAL STRUCTURE OF THE NTD OF DROSOPHILA OSKAR PROTEIN
Descriptor:Maternal effect protein oskar, GLYCEROL
Authors:Yang, N., Hu, M., Yu, Z., Wang, M., Lehmann, R., Xu, R.M.
Deposit date:2015-07-03
Release date:2015-09-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
5CD9
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CRYSTAL STRUCTURE OF THE CTD OF DROSOPHILA OSKAR PROTEIN
Descriptor:Maternal effect protein oskar, SULFATE ION
Authors:Yang, N., Hu, M., Yu, Z., Wang, M., Lehmann, R., Xu, R.M.
Deposit date:2015-07-03
Release date:2015-09-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
5C3I
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CRYSTAL STRUCTURE OF THE QUATERNARY COMPLEX OF HISTONE H3-H4 HETERODIMER WITH CHAPERONE ASF1 AND THE REPLICATIVE HELICASE SUBUNIT MCM2
Descriptor:Histone chaperone ASF1A, Histone H3.1, Histone H4, ...
Authors:Wang, H., Wang, M., Yang, N., Xu, R.M.
Deposit date:2015-06-17
Release date:2015-07-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Protein Cell, 6, 2015
5BTR
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CRYSTAL STRUCTURE OF SIRT1 IN COMPLEX WITH RESVERATROL AND AN AMC-CONTAINING PEPTIDE
Descriptor:NAD-dependent protein deacetylase sirtuin-1, AMC-containing peptide, ZINC ION, ...
Authors:Cao, D., Wang, M., Qiu, X., Liu, D., Jiang, H., Yang, N., Xu, R.M.
Deposit date:2015-06-03
Release date:2015-07-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Genes Dev., 29, 2015
4PSW
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
Descriptor:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ...
Authors:Yang, M., Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4PSX
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
Descriptor:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ...
Authors:Yang, M., Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4Q5W
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CRYSTAL STRUCTURE OF EXTENDED-TUDOR 9 OF DROSOPHILA MELANOGASTER
Descriptor:Maternal protein tudor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Ren, R., Liu, H., Wang, W., Wang, M., Yang, N., Dong, Y., Gong, W., Lehmann, R., Xu, R.M.
Deposit date:2014-04-17
Release date:2014-05-21
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structure and domain organization of Drosophila Tudor
Cell Res., 24, 2014
4Q5Y
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CRYSTAL STRUCTURE OF EXTENDED-TUDOR 10-11 OF DROSOPHILA MELANOGASTER
Descriptor:Maternal protein tudor
Authors:Liu, H., Ren, R., Wang, W., Wang, M., Yang, N., Dong, Y., Gong, W., Lehmann, R., Xu, R.M.
Deposit date:2014-04-18
Release date:2014-05-21
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and domain organization of Drosophila Tudor
Cell Res., 24, 2014
4PW5
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5HMC-CONTAINING DNA, COMPLEX I
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2
Authors:ZHou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW6
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5HMC-CONTAINING DNA, COMPLEX II
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2
Authors:Zhou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.789 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW7
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5MC-CONTAINING DNA
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5mC-containing DNA1, 5mC-containing DNA2
Authors:ZHou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-19
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
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