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4UBS
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BU of 4ubs by Molmil
The crystal structure of cytochrome P450 105D7 from Streptomyces avermitilis in complex with Diclofenac
Descriptor: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Xu, L.H, Ikeda, H, Arakawa, T, Wakagi, T, Shoun, H, Fushinobu, S.
Deposit date:2014-08-13
Release date:2014-11-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase.
Appl.Microbiol.Biotechnol., 99, 2015
3ABA
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BU of 3aba by Molmil
Crystal structure of CYP105P1 in complex with filipin I
Descriptor: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,28R)-3-hexyl-4,6,8,10,12,14,16-heptahydroxy-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Xu, L.H, Fushinobu, S, Takamatsu, S, Wakagi, T, Ikeda, H, Shoun, H.
Deposit date:2009-12-04
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis
J.Biol.Chem., 285, 2010
3ABB
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BU of 3abb by Molmil
Crystal structure of CYP105D6
Descriptor: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S, Takamatsu, S, Wakagi, T, Ikeda, H, Shoun, H.
Deposit date:2009-12-04
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis
J.Biol.Chem., 285, 2010
3E5J
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BU of 3e5j by Molmil
Crystal structure of CYP105P1 wild-type ligand-free form
Descriptor: Cytochrome P450 (Cytochrome P450 hydroxylase), PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S, Ikeda, H, Wakagi, T, Shoun, H.
Deposit date:2008-08-14
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of cytochrome P450 105P1 from Streptomyces avermitilis: conformational flexibility and histidine ligation state
J.Bacteriol., 191, 2009
3E5K
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BU of 3e5k by Molmil
Crystal structure of CYP105P1 wild-type 4-phenylimidazole complex
Descriptor: 4-PHENYL-1H-IMIDAZOLE, Cytochrome P450 (Cytochrome P450 hydroxylase), PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S, Ikeda, H, Wakagi, T, Shoun, H.
Deposit date:2008-08-14
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of cytochrome P450 105P1 from Streptomyces avermitilis: conformational flexibility and histidine ligation state
J.Bacteriol., 191, 2009
3E5L
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BU of 3e5l by Molmil
Crystal structure of CYP105P1 H72A mutant
Descriptor: Cytochrome P450 (Cytochrome P450 hydroxylase), PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S, Ikeda, H, Wakagi, T, Shoun, H.
Deposit date:2008-08-14
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of cytochrome P450 105P1 from Streptomyces avermitilis: conformational flexibility and histidine ligation state
J.Bacteriol., 191, 2009
7CL9
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BU of 7cl9 by Molmil
Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation
Descriptor: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, ...
Authors:Xu, L.H, Fushinobu, S.
Deposit date:2020-07-20
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation
To Be Published
7CL7
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BU of 7cl7 by Molmil
Substrate-free structure of CYP154C2 from Streptomyces avermitilis in an open conformation
Descriptor: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S.
Deposit date:2020-07-20
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate-free structure of CYP154C2 in an open conformation
To Be Published
6L69
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BU of 6l69 by Molmil
Crystal structure of CYP154C2 from Streptomyces avermitilis
Descriptor: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.H, Fushinobu, S.
Deposit date:2019-10-28
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis.
Biochem.Biophys.Res.Commun., 522, 2020
7CL8
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BU of 7cl8 by Molmil
Testosterone-bound structure of CYP154C2 from Streptomyces avermitilis in an closed conformation
Descriptor: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Xu, L.H, Fushinobu, S.
Deposit date:2020-07-20
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Improved 2 alpha-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design.
Appl.Environ.Microbiol., 89, 2023
7WEX
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BU of 7wex by Molmil
The crystal structure of substrate-free CYP107X1 from Streptomyces avermitilis
Descriptor: Cytochrome P450 hydroxylase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE
Authors:Xu, L.-H, Lin, S, Gao, L.
Deposit date:2021-12-24
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The 16 alpha-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis.
Chem.Biodivers., 19, 2022

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PDB entries from 2024-04-17

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