Author results

3HVN
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CRYSTAL STRUCTURE OF CYTOTOXIN PROTEIN SUILYSIN FROM STREPTOCOCCUS SUIS
分子名称:Hemolysin, 1,1,1,3,3,3-hexafluoropropan-2-ol, HEPTANE-1,2,3-TRIOL
著者Xu, L., Huang, B., Du, H., Zhang, C.X., Xu, J., Li, X., Rao, Z.
登録日2009-06-16
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.852 Å)
主引用文献Crystal structure of cytotoxin protein suilysin from Streptococcus suis
Protein Cell, 1, 2010
1N7U
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THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM I
分子名称:Adsorption protein P2, ACETATE ION, CALCIUM ION
著者Xu, L., Benson, S.D., Butcher, S.J., Bamford, D.H., Burnett, R.M.
登録日2002-11-18
公開日2003-04-08
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Receptor Binding Protein P2 of PRD1, a Virus Targeting Antibiotic-Resistant Bacteria, Has a Novel Fold Suggesting Multiple Functions.
Structure, 11, 2003
1N7V
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THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III
分子名称:Adsorption protein P2, ACETATE ION, CALCIUM ION
著者Xu, L., Benson, S.D., Butcher, S.J., Bamford, D.H., Burnett, R.M.
登録日2002-11-18
公開日2003-04-08
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Receptor Binding Protein P2 of PRD1, a Virus Targeting Antibiotic-Resistant Bacteria, Has a Novel Fold Suggesting Multiple Functions.
Structure, 11, 2003
2B1G
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CRYSTAL STRUCTURES OF TRANSITION STATE ANALOGUE INHIBITORS OF INOSINE MONOPHOSPHATE CYCLOHYDROLASE
分子名称:Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, POTASSIUM ION, ...
著者Xu, L., Chong, Y., Hwang, I., D'Onofrio, A., Amore, K., Beardsley, G.P., Li, C., Olson, A.J., Boger, D.L., Wilson, I.A.
登録日2005-09-15
公開日2006-11-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase.
J.Biol.Chem., 282, 2007
2B1I
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CRYSTAL STRUCTURES OF TRANSITION STATE ANALOGUE INHIBITORS OF INOSINE MONOPHOSPHATE CYCLOHYDROLASE
分子名称:Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, [3,4-DIHYDROXY-5R-(2,2,4-TRIOXO-1,2R,3S,4R-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-7-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE
著者Xu, L., Chong, Y., Hwang, I., D'Onofrio, A., Amore, K., Beardsley, G.P., Li, C., Olson, A.J., Boger, D.L., Wilson, I.A.
登録日2005-09-15
公開日2006-11-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase.
J.Biol.Chem., 282, 2007
2IU0
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CRYSTAL STRUCTURES OF TRANSITION STATE ANALOGUE INHIBITORS OF INOSINE MONOPHOSPHATE CYCLOHYDROLASE
分子名称:BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION, 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE
著者Xu, L., Chong, Y., Hwang, I., Onofrio, A.D., Amore, K., Beardsley, G.P., Li, C., Olson, A.J., Boger, D.L., Wilson, I.A.
登録日2006-05-26
公開日2007-02-20
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structure-Based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase
J.Biol.Chem., 282, 2007
2IU3
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CRYSTAL STRUCTURES OF TRANSITION STATE ANALOGUE INHIBITORS OF INOSINE MONOPHOSPHATE CYCLOHYDROLASE
分子名称:BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION, 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE
著者Xu, L., Chong, Y., Hwang, I., D'Onofrio, A., Amore, K., Beardsley, G.P., Li, C., Olson, A.J., Boger, D.L., Wilson, I.A.
登録日2006-05-27
公開日2007-02-20
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.
J. Biol. Chem., 282, 2007
5GI4
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DEAD-BOX RNA HELICASE
分子名称:ATP-dependent RNA helicase DeaD
著者Xu, L., Wang, L., Li, F., Wu, L., Shi, Y.
登録日2016-06-22
公開日2017-05-31
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
5GJU
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DEAD-BOX RNA HELICASE
分子名称:ATP-dependent RNA helicase DeaD, ADENOSINE MONOPHOSPHATE
著者Xu, L., Li, F., Wang, L., Shi, Y.
登録日2016-07-02
公開日2017-05-31
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
5B88
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RRM-LIKE DOMAIN OF DEAD-BOX PROTEIN, CSDA
分子名称:ATP-dependent RNA helicase DeaD
著者Xu, L., Peng, J., Zhang, J., Wu, J., Tang, Y., Shi, Y.
登録日2016-06-13
公開日2017-05-31
最終更新日2018-12-12
実験手法SOLUTION NMR
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
2INY
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NANOPOROUS CRYSTALS OF CHICKEN EMBRYO LETHAL ORPHAN (CELO) ADENOVIRUS MAJOR COAT PROTEIN, HEXON
分子名称:Hexon protein
著者Xu, L., Benson, S.D., Burnett, R.M.
登録日2006-10-09
公開日2007-02-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Nanoporous crystals of chicken embryo lethal orphan (CELO) adenovirus major coat protein, hexon.
J.Struct.Biol., 157, 2007
1THZ
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CRYSTAL STRUCTURE OF AVIAN AICAR TRANSFORMYLASE IN COMPLEX WITH A NOVEL INHIBITOR IDENTIFIED BY VIRTUAL LIGAND SCREENING
分子名称:Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, 2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC ACID
著者Xu, L., Li, C., Olson, A.J., Wilson, I.A.
登録日2004-06-01
公開日2004-09-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening.
J.Biol.Chem., 279, 2004
2ODM
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CRYSTAL STRUCTURE OF S. AUREUS YLAN, AN ESSENTIAL LEUCINE RICH PROTEIN INVOLVED IN THE CONTROL OF CELL SHAPE
分子名称:UPF0358 protein MW0995
著者Xu, L., Sedelnikova, S.E., Baker, P.J., Errington, J., Hunt, A., Rice, D.W.
登録日2006-12-23
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal structure of S. aureus YlaN, an essential leucine rich protein involved in the control of cell shape.
Proteins, 68, 2007
3FYM
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THE 1A STRUCTURE OF YMFM, A PUTATIVE DNA-BINDING MEMBRANE PROTEIN FROM STAPHYLOCOCCUS AUREUS
分子名称:Putative uncharacterized protein, ZINC ION
著者Xu, L., Sedelnikova, S.E., Baker, P.J., Rice, D.W.
登録日2009-01-22
公開日2010-02-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The 1A structure of YmfM, a putative DNA-binding membrane protein from Staphylococcus aureus
To be Published
3T42
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HUMAN ALDOSE REDUCTASE IN COMPLEX WITH A NITRILE-CONTAINING IDD INHIBITOR
分子名称:Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(4-cyano-3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ...
著者Xu, L., Cohen, A.E., Boxer, S.G.
登録日2011-07-25
公開日2011-10-05
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Electrostatic Fields near the Active Site of Human Aldose Reductase: 2. New Inhibitors and Complications Caused by Hydrogen Bonds.
Biochemistry, 50, 2011
5GH9
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CRYSTAL STRUCTURE OF CBP BROMODOMAIN WITH H3K56AC PEPTIDE
分子名称:CREB-binding protein, Histone H3
著者Xu, L.
登録日2016-06-19
公開日2017-06-21
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural insight into CBP bromodomain-mediated recognition of acetylated histone H3K56ac
FEBS J., 2017
2MU3
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SPIDER WRAPPING SILK FIBRE ARCHITECTURE ARISING FROM ITS MODULAR SOLUBLE PROTEIN PRECURSOR
分子名称:Aciniform spidroin 1
著者Xu, L., Tremblay, M., Meng, Q., Liu, X., Rainey, J.K., Lefevre, T., Sarker, M., Orrell, K.E., Leclerc, J., Pezolet, M., Auger, M.
登録日2014-09-03
公開日2015-07-08
実験手法SOLUTION NMR
主引用文献Spider wrapping silk fibre architecture arising from its modular soluble protein precursor.
Sci Rep, 5, 2015
5WYM
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CRYSTAL STRUCTURE OF AN ANTI-CONNEXIN26 SCFV
分子名称:anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain
著者Li, S., Xu, L.
登録日2017-01-13
公開日2018-01-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
Front Mol Neurosci, 10, 2017
3HI1
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STRUCTURE OF HIV-1 GP120 (CORE WITH V3) IN COMPLEX WITH CD4-BINDING-SITE ANTIBODY F105
分子名称:Glycoprotein 120, F105 Light Chain, F105 Heavy Chain, ...
著者Kwon, Y.D., Chen, L., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z., Zhang, M.-Y., Arthos, J., Burton, D.R., Dimitrov, D., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
登録日2009-05-18
公開日2009-11-17
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3IDX
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CRYSTAL STRUCTURE OF HIV-GP120 CORE IN COMPLEX WITH CD4-BINDING SITE ANTIBODY B13, SPACE GROUP C222
分子名称:HIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain, ...
著者Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
登録日2009-07-22
公開日2009-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3IDY
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CRYSTAL STRUCTURE OF HIV-GP120 CORE IN COMPLEX WITH CD4-BINDING SITE ANTIBODY B13, SPACE GROUP C2221
分子名称:HIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain, ...
著者Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
登録日2009-07-22
公開日2009-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3TTI
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CRYSTAL STRUCTURE OF JNK3 COMPLEXED WITH CC-930, AN ORALLY ACTIVE ANTI-FIBROTIC JNK INHIBITOR
分子名称:Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol, GLYCEROL
著者Plantevin-Krenitsky, V., Nadolny, L., Delgado, M., Ayala, L., Clareen, S., Hilgraf, R., Albers, R., Hegde, S., D'Sidocky, N., Sapienza, J., Wright, J., McCarrick, M., Bahmanyar, S., Chamberlain, P., Delker, S.L., Muir, J., Giegel, D., Xu, L., Celeridad, M., Lachowitzer, J., Bennett, B., Moghaddam, M., Khatsenko, O., Katz, J., Fan, R., Bai, A., Tang, Y., Shirley, M.A., Benish, B., Bodine, T., Blease, K., Raymon, H., Cathers, B.E., Satoh, Y.
登録日2011-09-14
公開日2012-02-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Bioorg.Med.Chem.Lett., 22, 2012
3TTJ
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CRYSTAL STRUCTURE OF JNK3 COMPLEXED WITH CC-359, A JNK INHIBITOR FOR THE PREVENTION OF ISCHEMIA-REPERFUSION INJURY
分子名称:Mitogen-activated protein kinase 10, 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine
著者Plantevin-Krenitsky, V., Delgado, M., Nadolny, L., Sahasrabudhe, K., Ayala, S., Clareen, S., Hilgraf, R., Albers, R., Kois, A., Hughes, K., Wright, J., Nowakowski, J., Sudbeck, E., Ghosh, S., Bahmanyar, S., Chamberlain, P., Muir, J., Cathers, B.E., Giegel, D., Xu, L., Celeridad, M., Moghaddam, M., Khatsenko, O., Omholt, P., Katz, J., Pai, S., Fan, R., Tang, Y., Shirley, M.A., Benish, B., Blease, K., Raymon, H., Bhagwat, S., Bennett, B., Satoh, Y.
登録日2011-09-14
公開日2012-01-25
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury.
Bioorg.Med.Chem.Lett., 22, 2012
2HJG
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THE CRYSTAL STRUCTURE OF THE B. SUBTILIS YPHC GTPASE IN COMPLEX WITH GDP
分子名称:GTP-binding protein engA, ZINC ION, GUANOSINE-5'-DIPHOSPHATE
著者Muench, S.P., Xu, L., Sedelnikova, S.E., Rice, D.W.
登録日2006-06-30
公開日2006-08-08
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6C8U
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SOLUTION STRUCTURE OF MUSASHI2 RRM1
分子名称:RNA-binding protein Musashi homolog 2
著者Xing, M., Lan, L., Douglas, J.T., Gao, P., Hanzlik, R.P., Xu, L.
登録日2018-01-25
公開日2019-01-30
最終更新日2019-02-20
実験手法SOLUTION NMR
主引用文献Solution structure of Musashi2 RRM1
To be Published