Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1Q2R
DownloadVisualize
BU of 1q2r by Molmil
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Descriptor: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), ...
Authors:Xie, W, Liu, X, Huang, R.H.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
1Q2S
DownloadVisualize
BU of 1q2s by Molmil
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Descriptor: 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, ...
Authors:Xie, W, Liu, X, Huang, R.H.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
6WW9
DownloadVisualize
BU of 6ww9 by Molmil
Crystal structure of human REV7(R124A)-SHLD3(35-58) complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3
Authors:Xie, W, Patel, D.J.
Deposit date:2020-05-08
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WWA
DownloadVisualize
BU of 6wwa by Molmil
Crystal structure of human SHLD2-SHLD3-REV7 complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera
Authors:Xie, W, Patel, D.J.
Deposit date:2020-05-08
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
3JZ3
DownloadVisualize
BU of 3jz3 by Molmil
Structure of the cytoplasmic segment of histidine kinase QseC
Descriptor: SULFATE ION, Sensor protein qseC
Authors:Xie, W, Kwiatkowski, W, Choe, S, Center for Structures of Membrane Proteins (CSMP)
Deposit date:2009-09-22
Release date:2010-07-21
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Cytoplasmic Segment of Histidine Kinase Receptor QseC, a Key Player in Bacterial Virulence.
Protein Pept.Lett., 17, 2010
7SHO
DownloadVisualize
BU of 7sho by Molmil
Crystal structure of hSTING in complex with c[2',3'-(ara-2'-G, ribo-3'-A)-MP] (RJ242)
Descriptor: (2R,5R,7R,8S,10R,12aR,14R,15R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:Xie, W, Lama, L, Yang, X.J, Kuryavyi, V, Nudelman, I, Glickman, J.F, Jones, R.A, Tuschl, T, Patel, D.J.
Deposit date:2021-10-10
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists.
Cell Chem Biol, 2023
7SHP
DownloadVisualize
BU of 7shp by Molmil
Crystal structure of hSTING in complex with c[2',3'-(ribo-2'-G, xylo-3'-A)-MP](RJ244)
Descriptor: (2S,5R,7R,8R,10S,12aR,14R,15R,15aR,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:Xie, W, Lama, L, Yang, X.J, Kuryavyi, V, Nudelman, I, Glickman, J.F, Jones, R.A, Tuschl, T, Patel, D.J.
Deposit date:2021-10-11
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists.
Cell Chem Biol, 2023
2PMF
DownloadVisualize
BU of 2pmf by Molmil
The crystal structure of a human glycyl-tRNA synthetase mutant
Descriptor: CHLORIDE ION, GLYCEROL, Glycyl-tRNA synthetase
Authors:Xie, W.
Deposit date:2007-04-21
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PME
DownloadVisualize
BU of 2pme by Molmil
The Apo crystal Structure of the glycyl-tRNA synthetase
Descriptor: Glycyl-tRNA synthetase
Authors:Xie, W.
Deposit date:2007-04-21
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7L9P
DownloadVisualize
BU of 7l9p by Molmil
Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ...
Authors:Xie, W, Patel, D.J.
Deposit date:2021-01-04
Release date:2021-03-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
6EDC
DownloadVisualize
BU of 6edc by Molmil
hcGAS-16bp dsDNA complex
Descriptor: Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ...
Authors:Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
Deposit date:2018-08-09
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6EDB
DownloadVisualize
BU of 6edb by Molmil
Crystal structure of SRY.hcGAS-21bp dsDNA complex
Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*CP*GP*GP*GP*AP*TP*CP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*TP*TP*GP*TP*TP*TP*AP*GP*AP*TP*CP*CP*CP*GP*GP*AP*TP*C)-3'), Sex-determining region Y protein,Cyclic GMP-AMP synthase, ...
Authors:Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
Deposit date:2018-08-09
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
5CO4
DownloadVisualize
BU of 5co4 by Molmil
Structural insights into the 2-OH methylation of C/U34 on tRNA
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Putative tRNA (cytidine(34)-2'-O)-methyltransferase
Authors:Xie, W, Pang, P, Wang, Z.
Deposit date:2015-07-19
Release date:2016-07-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the 2-OH methylation of C34 or U34 on tRNA
To Be Published
5EGN
DownloadVisualize
BU of 5egn by Molmil
Est816 as an N-Acyl homoserine lactone degrading enzyme
Descriptor: Esterase
Authors:Xie, W, Liu, X, Cao, L, Liu, Y.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.636 Å)
Cite:Est816 as an N-Acyl homoserine lactone degrading enzyme
To Be Published
8HVJ
DownloadVisualize
BU of 8hvj by Molmil
The structure of the E. coli mRNA endoonuclease YiCC
Descriptor: UPF0701 protein YicC
Authors:Xie, W, Hunag, L.
Deposit date:2022-12-27
Release date:2023-12-27
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:The structure of the E. coli mRNA endoonuclease YiCC
To Be Published
6O47
DownloadVisualize
BU of 6o47 by Molmil
human cGAS core domain (K427E/K428E) bound with RU-521
Descriptor: (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ...
Authors:Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
Deposit date:2019-02-28
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
7VWN
DownloadVisualize
BU of 7vwn by Molmil
The structure of an engineered PET hydrolase
Descriptor: CHLORIDE ION, Poly(ethylene terephthalate) hydrolase
Authors:Xie, W, Jia, Q.
Deposit date:2021-11-11
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:An engineered PET hydrolase for biodegradation of microplastics in ocean water
To Be Published
7D88
DownloadVisualize
BU of 7d88 by Molmil
Crystal structure of a novel thermostable GH10 xylanase XynA
Descriptor: Beta-xylanase, CALCIUM ION
Authors:Xie, W, Yu, Q, Wang, C.
Deposit date:2020-10-07
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.34482026 Å)
Cite:Insights into the Catalytic Mechanism of a Novel XynA and Structure-Based Engineering for Improving Bifunctional Activities.
Biochemistry, 60, 2021
7D89
DownloadVisualize
BU of 7d89 by Molmil
Crystal structure of an inactivated double mutant (E182AE280A) of a novel thermostable GH10 xylanase XynA
Descriptor: Beta-xylanase, CALCIUM ION
Authors:Xie, W, Yu, Q, Wang, C.
Deposit date:2020-10-07
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89384079 Å)
Cite:Insights into the Catalytic Mechanism of a Novel XynA and Structure-Based Engineering for Improving Bifunctional Activities.
Biochemistry, 60, 2021
7DLC
DownloadVisualize
BU of 7dlc by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with N1-methylguanosine
Descriptor: 2-azanyl-9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-purin-6-one, Guanosine deaminase, ZINC ION
Authors:Xie, W, Jia, Q, Zeng, H.
Deposit date:2020-11-27
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Asymmetric Catalysis of Arabidopsis thaliana Guanosine Deaminase Revealed by Crystal Structures
To Be Published
7DOX
DownloadVisualize
BU of 7dox by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in complex with m7G
Descriptor: 7-METHYLGUANOSINE, Guanosine deaminase, ZINC ION
Authors:Xie, W, Jia, Q, Zeng, H.
Deposit date:2020-12-17
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Asymmetric Catalysis of Arabidopsis thaliana Guanosine Deaminase Revealed by Crystal Structures
To Be Published
7DOY
DownloadVisualize
BU of 7doy by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in complex with 6-O-methylguanosine
Descriptor: (2R,3R,4S,5R)-2-(2-azanyl-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Guanosine deaminase, ZINC ION
Authors:Xie, W, Jia, Q, Zeng, H.
Deposit date:2020-12-17
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Asymmetric Catalysis of Arabidopsis thaliana Guanosine Deaminase Revealed by Crystal Structures
To Be Published
7DOW
DownloadVisualize
BU of 7dow by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine
Descriptor: 2-azanyl-7-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one, Guanosine deaminase, ZINC ION
Authors:Xie, W, Jia, Q, Zeng, H.
Deposit date:2020-12-17
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Asymmetric Catalysis of Arabidopsis thaliana Guanosine Deaminase Revealed by Crystal Structures
To Be Published
7DPK
DownloadVisualize
BU of 7dpk by Molmil
The structure of the exchange reaction of the Arabidopsis thaliana guanosine deaminase in complex with 7-deazaguaosine by guanosine
Descriptor: 2,3-dihydroxanthosine, Guanosine deaminase, ZINC ION
Authors:Xie, W, Jia, Q, Zeng, H.
Deposit date:2020-12-19
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Asymmetric Catalysis of Arabidopsis thaliana Guanosine Deaminase Revealed by Crystal Structures
To Be Published
7JW2
DownloadVisualize
BU of 7jw2 by Molmil
Crystal structure of Aedes aegypti Nibbler EXO domain
Descriptor: Exonuclease mut-7 homolog
Authors:Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
Deposit date:2020-08-24
Release date:2021-01-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon