Author results

6BZ9
  • Download 6bz9
  • View 6bz9
Molmil generated image of 6bz9
CRYSTAL STRUCTURE OF HUMAN CASPASE-1 IN COMPLEX WITH AC-FLTD-CMK
分子名称:Caspase-1, Ac-FLTD-CMK, DI(HYDROXYETHYL)ETHER
著者Xiao, T.S., Yang, J., Liu, Z., Wang, C., Yang, R.
登録日2017-12-22
公開日2018-06-13
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3VD8
  • Download 3vd8
  • View 3vd8
Molmil generated image of 3vd8
CRYSTAL STRUCTURE OF HUMAN AIM2 PYD DOMAIN WITH MBP FUSION
分子名称:Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, 1,2-ETHANEDIOL, ...
著者Jin, T.C., Perry, A., Smith, P., Xiao, T.S.
登録日2012-01-04
公開日2013-01-16
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.0685 Å)
主引用文献Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly.
J.Biol.Chem., 288, 2013
4EO7
  • Download 4eo7
  • View 4eo7
Molmil generated image of 4eo7
CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN 88.
分子名称:Myeloid differentiation primary response protein MyD88, MAGNESIUM ION
著者Snyder, G.A., Cirl, C., Jiang, J.S., Chen, P., Smith, T., Xiao, T.S.
登録日2012-04-13
公開日2013-04-10
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LQC
  • Download 4lqc
  • View 4lqc
Molmil generated image of 4lqc
THE CRYSTAL STRUCTURES OF THE BRUCELLA PROTEIN TCPB AND THE TLR ADAPTOR PROTEIN TIRAP SHOW STRUCTURAL DIFFERENCES IN MICROBIAL TIR MIMICRY.
分子名称:TcpB
著者Snyder, G.A., Smith, P., Fresquez, T., Cirl, C., Jiang, J., Snyder, N., Luchetti, T., Miethke, T., Xiao, T.S.
登録日2013-07-17
公開日2013-12-04
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
J.Biol.Chem., 289, 2014
4LQD
  • Download 4lqd
  • View 4lqd
Molmil generated image of 4lqd
THE CRYSTAL STRUCTURES OF THE BRUCELLA PROTEIN TCPB AND THE TLR ADAPTOR PROTEIN TIRAP SHOW STRUCTURAL DIFFERENCES IN MICROBIAL TIR MIMICRY
分子名称:Toll/interleukin-1 receptor domain-containing adapter protein, GLYCEROL
著者Snyder, G.A., Smith, P., Jiang, J., Xiao, T.S.
登録日2013-07-17
公開日2013-12-04
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
J.Biol.Chem., 289, 2014
4M6B
  • Download 4m6b
  • View 4m6b
Molmil generated image of 4m6b
CRYSTAL STRUCTURE OF YEAST SWR1-Z DOMAIN IN COMPLEX WITH H2A.Z-H2B DIMER
分子名称:Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1
著者Hong, J.J., Feng, H.Q., Wang, F., Ranjan, A., Chen, J.H., Jiang, J.S., Girlando, R., Xiao, T.S., Wu, C., Bai, Y.W.
登録日2013-08-09
公開日2014-02-19
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer.
Mol.Cell, 53, 2014
4QLC
  • Download 4qlc
  • View 4qlc
Molmil generated image of 4qlc
CRYSTAL STRUCTURE OF CHROMATOSOME AT 3.5 ANGSTROM RESOLUTION
分子名称:DNA (167-mer), Histone H3, Histone H4, ...
著者Jiang, J.S., Zhou, B.R., Xiao, T.S., Bai, Y.W.
登録日2014-06-11
公開日2015-07-22
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Structural Mechanisms of Nucleosome Recognition by Linker Histones.
Mol.Cell, 33 Suppl 1, 2015
5H7N
  • Download 5h7n
  • View 5h7n
Molmil generated image of 5h7n
CRYSTAL STRUCTURE OF HUMAN NLRP12-PYD WITH A MBP TAG
分子名称:NLRP12-PYD with MBP tag, MALTOTETRAOSE, SULFATE ION, ...
著者Jin, T.C., Xiao, T.S.
登録日2016-11-19
公開日2017-02-15
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5H7Q
  • Download 5h7q
  • View 5h7q
Molmil generated image of 5h7q
CRYSTAL STRUCTURE OF HUMAN MNDA PYD DOMAIN WITH MBP TAG
分子名称:MNDA PYD domain with MBP tag, MALTOSE, ACETATE ION
著者Jin, T.C., Xiao, T.S.
登録日2016-11-20
公開日2017-02-15
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5WPZ
  • Download 5wpz
  • View 5wpz
Molmil generated image of 5wpz
CRYSTAL STRUCTURE OF MNDA PYD WITH MBP TAG
分子名称:MBP-hMNDA-PYD, MALTOSE
著者Jin, T.C., Xiao, T.S.
登録日2016-11-22
公開日2017-02-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5WQ6
  • Download 5wq6
  • View 5wq6
Molmil generated image of 5wq6
CRYSTAL STRUCTURE OF HMNDA-PYD WITH MBP TAG
分子名称:MBP tagged hMNDA-PYD, MALTOSE, 1,2-ETHANEDIOL, ...
著者Jin, T.C., Xiao, T.S.
登録日2016-11-23
公開日2017-02-15
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5Y3S
  • Download 5y3s
  • View 5y3s
Molmil generated image of 5y3s
CRYSTAL STRUCTURE OF HUMAN NLRP1 LEUCINE RICH REPEAT DOMAIN
分子名称:NACHT, LRR and PYD domains-containing protein 1, PHOSPHATE ION, ...
著者Jin, T., Xiao, T.S.
登録日2017-07-30
公開日2018-08-01
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Crystal structure of human NLRP1 LRR domain
To Be Published
5Z7D
  • Download 5z7d
  • View 5z7d
Molmil generated image of 5z7d
P204HINAB-DSDNA COMPLEX STRUCTURE
分子名称:Interferon-activable protein 204, DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3')
著者Jin, T., Jiang, J., Xiao, T.S.
登録日2018-01-28
公開日2019-01-30
実験手法X-RAY DIFFRACTION (4.504 Å)
主引用文献p204-HINab:dsDNA complex structure
To Be Published
6AO3
  • Download 6ao3
  • View 6ao3
Molmil generated image of 6ao3
CRYSTAL STRUCTURE OF THE MURINE GASDERMIN D C-TERMINAL DOMAIN
分子名称:Gasdermin-D
著者Liu, Z., Wang, C., Yang, J., Xiao, T.S.
登録日2017-08-15
公開日2018-04-11
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Structure, 26, 2018
6AO4
  • Download 6ao4
  • View 6ao4
Molmil generated image of 6ao4
CRYSTAL STRUCTURE OF THE HUMAN GASDERMIN D C-TERMINAL DOMAIN
分子名称:Gasdermin-D
著者Liu, Z., Wang, C., Yang, J., Xiao, T.S.
登録日2017-08-15
公開日2018-04-11
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Structure, 26, 2018
3R9M
  • Download 3r9m
  • View 3r9m
Molmil generated image of 3r9m
CRYSTAL STRUCTURE OF THE BROX BRO1 DOMAIN
分子名称:BRO1 domain-containing protein BROX, 1,2-ETHANEDIOL, FORMIC ACID
著者Mu, R.L., Jiang, J.S., Snyder, G., Smith, P., Xiao, T.
登録日2011-03-25
公開日2011-09-14
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
3RAU
  • Download 3rau
  • View 3rau
Molmil generated image of 3rau
CRYSTAL STRUCTURE OF THE HD-PTP BRO1 DOMAIN
分子名称:Tyrosine-protein phosphatase non-receptor type 23, ACETATE ION, 1,2-ETHANEDIOL, ...
著者Mu, R.L., Jiang, J.S., Snyder, G., Smith, P., Xiao, T.
登録日2011-03-28
公開日2011-09-14
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
3RLN
  • Download 3rln
  • View 3rln
Molmil generated image of 3rln
STRUCTURAL BASIS OF CYTOSOLIC DNA RECOGNITION BY INNATE IMMUNE RECEPTORS
分子名称:Gamma-interferon-inducible protein 16
著者Jin, T.C., Xiao, T.
登録日2011-04-19
公開日2012-04-25
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
3RLO
  • Download 3rlo
  • View 3rlo
Molmil generated image of 3rlo
STRUCTURAL BASIS OF CYTOSOLIC DNA RECOGNITION BY INNATE RECEPTORS
分子名称:Gamma-interferon-inducible protein 16, 1,2-ETHANEDIOL, FORMIC ACID
著者Jin, T.C., Xiao, T.
登録日2011-04-19
公開日2012-04-25
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
3RN2
  • Download 3rn2
  • View 3rn2
Molmil generated image of 3rn2
STRUCTURAL BASIS OF CYTOSOLIC DNA RECOGNITION BY INNATE IMMUNE RECEPTORS
分子名称:Interferon-inducible protein AIM2, DNA (5'-D(*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*TP*CP*TP*TP*TP*GP*AP*TP*GP*G)-3'), 1,2-ETHANEDIOL
著者Jin, T.C., Xiao, T.
登録日2011-04-21
公開日2012-04-25
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
3RN5
  • Download 3rn5
  • View 3rn5
Molmil generated image of 3rn5
STRUCTURAL BASIS OF CYTOSOLIC DNA RECOGNITION BY INNATE IMMUNE RECEPTORS
分子名称:Interferon-inducible protein AIM2, DNA (5'-D(*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*AP*AP*GP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*TP*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*G)-3'), ...
著者Jin, T.C., Xiao, T.
登録日2011-04-21
公開日2012-04-25
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
3RNU
  • Download 3rnu
  • View 3rnu
Molmil generated image of 3rnu
STRUCTURAL BASIS OF CYTOSOLIC DNA SENSING BY INNATE IMMUNE RECEPTORS
分子名称:Gamma-interferon-inducible protein 16, DNA (5'-D(*GP*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*GP*GP*CP*C)-3'), ...
著者Jin, T.C., Xiao, T.
登録日2011-04-22
公開日2012-04-25
最終更新日2015-01-28
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
Immunity, 36, 2012
3ULY
  • Download 3uly
  • View 3uly
Molmil generated image of 3uly
CRYSTAL STRUCTURE OF BROX BRO1 DOMAIN IN COMPLEX WITH THE C-TERMINAL TAILS OF CHMP5
分子名称:BRO1 domain-containing protein BROX, Charged multivesicular body protein 5, GLYCEROL
著者Jiang, J.S., Mu, R.L., Xiao, T.
登録日2011-11-11
公開日2012-04-18
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Structure, 20, 2012
3UM0
  • Download 3um0
  • View 3um0
Molmil generated image of 3um0
CRYSTAL STRUCTURE OF THE BROX BRO1 DOMAIN IN COMPLEX WITH THE C-TERMINAL TAIL OF CHMP5
分子名称:BRO1 domain-containing protein BROX, Charged multivesicular body protein 5, GLYCEROL
著者Jiang, J.S., Mu, R.L., Xiao, T.
登録日2011-11-11
公開日2012-04-18
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Structure, 20, 2012
3UM1
  • Download 3um1
  • View 3um1
Molmil generated image of 3um1
CRYSTAL STRUCTURE OF THE BROX BRO1 DOMAIN IN COMPLEX WITH THE C-TERMINAL TAIL OF CHMP5
分子名称:BRO1 domain-containing protein BROX, Charged multivesicular body protein 5, GLYCEROL
著者Jiang, J.S., Mu, R.L., Xiao, T.
登録日2011-11-11
公開日2012-04-18
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Structure, 20, 2012
<12>