Author results

3HD2
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CRYSTAL STRUCTURE OF E. COLI HPPK(Q50A) IN COMPLEX WITH MGAMPCPP AND PTERIN
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-05-06
Release date:2010-05-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Role of loop coupling in enzymatic catalysis and conformational dynamics
To be Published
3HSJ
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CRYSTAL STRUCTURE OF E. COLI HPPK(N55A)
Descriptor:HPPK, ACETATE ION, GLYCEROL
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-06-10
Release date:2010-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
1HQ2
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-12-13
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1Q0N
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE FROM E. COLI WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-07-16
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Catalytic Center Assembly of Hppk as Revealed by the Crystal Structure of a Ternary Complex at 1.25 A Resolution
Structure, 8, 2000
1TMM
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CRYSTAL STRUCTURE OF TERNARY COMPLEX OF E.COLI HPPK(W89A) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Li, Y., Wu, Y., Shi, G., Ji, X., Yan, H.
Deposit date:2004-06-10
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
Biochemistry, 44, 2005
3HD1
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CRYSTAL STRUCTURE OF E. COLI HPPK(N10A) IN COMPLEX WITH MGAMPCPP
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-05-06
Release date:2010-05-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Role of loop coupling in enzymatic catalysis and conformational dynamics
To be Published
1RTZ
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CRYSTAL STRUCTURE OF E.COLI APO-HPPK(V83G/DEL84-89) AT 1.33 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
1RB0
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CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI HPPK WITH 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.35 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-10-31
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Structure, 12, 2004
1RU1
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.40 ANGSTROM RESOLUTION (MONOCLINIC FORM)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
3HSZ
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CRYSTAL STRUCTURE OF E. COLI HPPK(F123A)
Descriptor:HPPK, CHLORIDE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-06-11
Release date:2010-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
3HT0
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CRYSTAL STRUCTURE OF E. COLI HPPK(F123A) IN COMPLEX WITH MGAMPCPP
Descriptor:HPPK, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-06-11
Release date:2010-06-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
1TMJ
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CRYSTAL STRUCTURE OF E.COLI APO-HPPK(W89A) AT 1.45 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION
Authors:Blaszczyk, J., Ji, X.
Deposit date:2004-06-10
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
Biochemistry, 44, 2005
3ILI
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CRYSTAL STRUCTURE OF E. COLI HPPK(D95A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-08-07
Release date:2010-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and functional roles of residues D95 and D97 in E. coli HPPK
To be Published
4RAX
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A REGULATORY DOMAIN OF AN ION CHANNEL
Descriptor:Piezo-type mechanosensitive ion channel component 1
Authors:Ge, J., Yang, M.
Deposit date:2014-09-11
Release date:2015-09-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Architecture of the mammalian mechanosensitive Piezo1 channel.
Nature, 527, 2015
1RU2
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN AT 1.48 ANGSTROM RESOLUTION (ORTHORHOMBIC FORM)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
1ZNI
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INSULIN
Descriptor:INSULIN, ZINC ION, CHLORIDE ION
Authors:Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
1EQM
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CRYSTAL STRUCTURE OF BINARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE WITH ADENOSINE-5'-DIPHOSPHATE
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Xiao, B., Blaszczyk, J., Ji, X.
Deposit date:2000-04-05
Release date:2001-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR.
J.Biol.Chem., 276, 2001
1F9H
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-07-10
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1HKA
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6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE
Authors:Xiao, B., Shi, G., Chen, X., Yan, H., Ji, X.
Deposit date:1998-09-29
Release date:1999-06-08
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents.
Structure Fold.Des., 7, 1999
2BQZ
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
Descriptor:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
Deposit date:2005-04-28
Release date:2005-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
3KUE
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CRYSTAL STRUCTURE OF E. COLI HPPK(E77A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, ACETATE ION
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-11-27
Release date:2010-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.538 Å)
Cite:Roles of residues E77 and H115 in E. coli HPPK
To be Published
1KBR
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CRYSTAL STRUCTURE OF UNLIGATED HPPK(R92A) FROM E.COLI AT 1.55 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION
Authors:Blaszczyk, J., Ji, X.
Deposit date:2001-11-06
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
6AP9
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CRYSTAL STRUCTURE OF HGSTP1-1 WITH S-NITROSATION OF CYS101
Descriptor:Glutathione S-transferase P, GLUTATHIONE, OXIDIZED GLUTATHIONE DISULFIDE, ...
Authors:Kumari, V., Ji, X.
Deposit date:2017-08-17
Release date:2018-08-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Cysteine S-nitrosylation of hGSTP1-1 by nitric oxide (NO)-releasing prodrugs
to be published
1RAO
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK WITH AMP AND 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.56 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ADENOSINE MONOPHOSPHATE, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-10-31
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Structure, 12, 2004
1G4C
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CRYSTAL STRUCTURE OF A COMPLEX OF HPPK(R92A) FROM E.COLI WITH MG2+ AT 1.65 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, CHLORIDE ION
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-10-26
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003