Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1LKN
DownloadVisualize
BU of 1lkn by Molmil
Solution NMR Structure of Protein TM_1112 from Thermotoga maritima. Ontario Centre for Structural Proteomics Target TM1112_1_89; Northeast Structural Genomics Consortium Target VT74.
Descriptor: hypothetical protein tm1112
Authors:Xia, Y, Yee, A, Semesi, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-04-25
Release date:2003-06-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure of Hypothetical Protein tm1112
to be published
7F3N
DownloadVisualize
BU of 7f3n by Molmil
Structure of PopP2 in apo form
Descriptor: Type III effector protein popp2
Authors:Xia, Y, Zhang, Z.M.
Deposit date:2021-06-16
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.351856 Å)
Cite:Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase.
Nat Commun, 12, 2021
7F32
DownloadVisualize
BU of 7f32 by Molmil
Ny-Hydroxyasparagine: A Multifunctional Unnatural Amino Acid That is a Good P1 Substrate of Asparaginyl Peptide Ligases
Descriptor: SYCNCLCRRGVCRCICTI
Authors:Xia, Y, Liu, C.F.
Deposit date:2021-06-15
Release date:2022-09-07
Method:SOLUTION NMR
Cite:N gamma-Hydroxyasparagine: A Multifunctional Unnatural Amino Acid That is a Good P1 Substrate of Asparaginyl Peptide Ligases.
Angew.Chem.Int.Ed.Engl., 60, 2021
5GNV
DownloadVisualize
BU of 5gnv by Molmil
Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain
Descriptor: Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION
Authors:Shang, Y, Xia, Y, Zhu, R, Zhu, J.
Deposit date:2016-07-25
Release date:2017-08-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
4N1Z
DownloadVisualize
BU of 4n1z by Molmil
Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1222
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Liu, Y.L, Xia, Y, Zhang, Y, Verma, I, Oldfield, E.
Deposit date:2013-10-04
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
Sci Transl Med, 6, 2014
4LQT
DownloadVisualize
BU of 4lqt by Molmil
1.10A resolution crystal structure of a superfolder green fluorescent protein (W57A) mutant
Descriptor: 1,2-ETHANEDIOL, Green fluorescent protein
Authors:Lovell, S, Xia, Y, Vo, B, Battaile, K.P, Egan, C, Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
4LQU
DownloadVisualize
BU of 4lqu by Molmil
1.60A resolution crystal structure of a superfolder green fluorescent protein (W57G) mutant
Descriptor: Green fluorescent protein
Authors:Lovell, S, Xia, Y, Vo, B, Battaile, K.P, Egan, C, Karanicolas, J.
Deposit date:2013-07-19
Release date:2013-12-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
J.Am.Chem.Soc., 135, 2013
8GV3
DownloadVisualize
BU of 8gv3 by Molmil
The cryo-EM structure of GSNOR with NYY001
Descriptor: (4P)-4-{2-[4-(1H-imidazol-1-yl)phenyl]-5-[3-oxo-3-(2-oxo-1,3-thiazolidin-3-yl)propyl]-1H-pyrrol-1-yl}-3-methylbenzamide, Alcohol dehydrogenase class-3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Xia, Y, Zhang, Q, Yao, D, Zhao, S, Xie, L, Ji, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:The cryo-EM structure of GSNOR with NYY001
To Be Published
7YFK
DownloadVisualize
BU of 7yfk by Molmil
The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin
Descriptor: Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
Authors:Xia, Y, Yao, D, Huang, C, Cao, Y.
Deposit date:2022-07-08
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Nat Commun, 14, 2023
7JUA
DownloadVisualize
BU of 7jua by Molmil
Crystal structure of the second heterocyclization domain of yersiniabactin synthetase at 2.35 A resolution
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
Authors:Xia, Y, Soule, J, Dowling, D.P.
Deposit date:2020-08-19
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 2022
7JTJ
DownloadVisualize
BU of 7jtj by Molmil
Crystal structure of the second heterocyclization domain of yersiniabactin synthetase
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Irp2 protein, SODIUM ION
Authors:Xia, Y, Gnann, A.D, Dowling, D.P.
Deposit date:2020-08-17
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
J.Biol.Chem., 298, 2022
5KSJ
DownloadVisualize
BU of 5ksj by Molmil
Crystal structure of deoxygenated hemoglobin in complex with Sphingosine phosphate
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Ahmed, M.H, Safo, M.K, Xia, Y.
Deposit date:2016-07-08
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
6X5J
DownloadVisualize
BU of 6x5j by Molmil
Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors
Descriptor: 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, Coagulation factor IX, ...
Authors:Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S.
Deposit date:2020-05-26
Release date:2020-06-24
Method:X-RAY DIFFRACTION (2.513 Å)
Cite:Discovery of hydroxy pyrimidine Factor IXa inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
6X5L
DownloadVisualize
BU of 6x5l by Molmil
Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors
Descriptor: 4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide, CITRIC ACID, Coagulation factor IX, ...
Authors:Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S.
Deposit date:2020-05-26
Release date:2020-06-24
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Discovery of hydroxy pyrimidine Factor IXa inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
6X5P
DownloadVisualize
BU of 6x5p by Molmil
Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors
Descriptor: 3-chloro-4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide, CITRIC ACID, Coagulation factor IX, ...
Authors:Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S.
Deposit date:2020-05-26
Release date:2020-06-24
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Discovery of hydroxy pyrimidine Factor IXa inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
5KSI
DownloadVisualize
BU of 5ksi by Molmil
Crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-Bisphosphoglycerate
Descriptor: (2R)-2,3-diphosphoglyceric acid, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, ...
Authors:Ahmed, M.H, Safo, M.K, Xia, Y.
Deposit date:2016-07-08
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
8GV9
DownloadVisualize
BU of 8gv9 by Molmil
The cryo-EM structure of hAE2 with chloride ion
Descriptor: Anion exchange protein 2, CHLORIDE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GV8
DownloadVisualize
BU of 8gv8 by Molmil
The cryo-EM structure of hAE2 with DIDS
Descriptor: 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
5SXY
DownloadVisualize
BU of 5sxy by Molmil
The solution NMR structure for the PqqD truncation of Methylobacterium extorquens PqqCD representing a functional and stand-alone ribosomally synthesized and post-translational modified (RiPP) recognition element (RRE)
Descriptor: Bifunctional coenzyme PQQ synthesis protein C/D
Authors:Evans, R.L, Xia, Y, Wilmot, C.M.
Deposit date:2016-08-10
Release date:2017-05-24
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone.
Biochemistry, 56, 2017
4A4T
DownloadVisualize
BU of 4a4t by Molmil
UNAC Tetraloops: To What Extent Can They Mimic GNRA Tetraloops
Descriptor: 5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*UP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q, Huang, H, Nagaswamy, U, Xia, Y, Gao, X, Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4S
DownloadVisualize
BU of 4a4s by Molmil
UNAC Tetraloops: To What Extent Can They Mimic GNRA Tetraloops
Descriptor: 5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*CP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q, Huang, H, Nagaswamy, U, Xia, Y, Gao, X, Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4R
DownloadVisualize
BU of 4a4r by Molmil
UNAC Tetraloops: To What Extent Can They Mimic GNRA Tetraloops
Descriptor: 5'-R(*GMP*GP*AP*CP*CP*CP*GP*GP*CP*UP*AP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q, Huang, H, Nagaswamy, U, Xia, Y, Gao, X, Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
4A4U
DownloadVisualize
BU of 4a4u by Molmil
UNAC Tetraloops: To What Extent Can They Mimic GNRA Tetraloops
Descriptor: 5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*GP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3'
Authors:Zhao, Q, Huang, H, Nagaswamy, U, Xia, Y, Gao, X, Fox, G.
Deposit date:2011-10-20
Release date:2012-05-30
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
2N9B
DownloadVisualize
BU of 2n9b by Molmil
Solution NMR Structure of Antiparallel Myosin-10:GCN4 Tandem Coiled-Coil
Descriptor: Unconventional myosin-X, General control protein GCN4 fusion
Authors:Vavra, K.C, Xia, Y, Rock, R.S.
Deposit date:2015-11-12
Release date:2016-06-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection
Biophys.J., 110, 2016
1IAY
DownloadVisualize
BU of 1iay by Molmil
CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH COFACTOR PLP AND INHIBITOR AVG
Descriptor: 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, 2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Huai, Q, Xia, Y, Chen, Y, Callahan, B, Li, N, Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon