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3PUM
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CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207
Descriptor:Capsid
Authors:Chen, Y., Tan, M., Xia, M., Hao, N., Zhang, X.C., Huang, P., Jiang, X., Li, X., Rao, Z.
Deposit date:2010-12-06
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens
Plos Pathog., 7, 2011
3PUN
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CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207 WITH LEWIS Y TETRASACCHARIDE
Descriptor:Capsid, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
Authors:Chen, Y., Tan, M., Xia, M., Hao, N., Zhang, X.C., Huang, P., Jiang, X., Li, X., Rao, Z.
Deposit date:2010-12-06
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens
Plos Pathog., 7, 2011
3PVD
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CRYSTAL STRUCTURE OF P DOMAIN DIMER OF NOROVIRUS VA207 COMPLEXED WITH 3'-SIALYL-LEWIS X TETRASACCHARIDE
Descriptor:Capsid, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Chen, Y., Tan, M., Xia, M., Hao, N., Zhang, X.C., Huang, P., Jiang, X., Li, X., Rao, Z.
Deposit date:2010-12-06
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens
Plos Pathog., 7, 2011
4RDJ
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN
Descriptor:Capsid
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
4RDK
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN IN COMPLEX WITH LEWIS B TETRASACCHARIDE
Descriptor:Capsid, ALPHA-L-FUCOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
4RDL
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN IN COMPLEX WITH LEWIS Y TETRASACCHARIDE
Descriptor:Capsid, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
4RLZ
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CRYSTAL STRUCTURE OF NOROVIRUS OIF P DOMAIN
Descriptor:Capsid protein, GLYCEROL
Authors:Liu, W., Chen, Y., Tan, M., Xia, M., Li, X., Jiang, X., Rao, Z.
Deposit date:2014-10-18
Release date:2015-06-24
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4RM0
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CRYSTAL STRUCTURE OF NOROVIRUS OIF P DOMAIN IN COMPLEX WITH LEWIS A TRISACCHARIDE
Descriptor:Capsid protein, ALPHA-L-FUCOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, W., Chen, Y., Tan, M., Xia, M., Li, X., Jiang, X., Rao, Z.
Deposit date:2014-10-18
Release date:2015-06-24
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
3BQJ
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VA387 POLYPEPTIDE
Descriptor:va387 polypeptide
Authors:Bu, W., Mamedova, A., Tan, M., Jiang, J., Hegde, R.
Deposit date:2007-12-20
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
3BY1
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UNLIGANDED NORVALK VIRUS P DOMAIN
Descriptor:58 kd capsid protein
Authors:Hegde, R., Bu, W.
Deposit date:2008-01-15
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
3BY2
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NORWALK P POLYPEPTIDE (228-523)
Descriptor:58 kd capsid protein
Authors:Hegde, R., Bu, W.
Deposit date:2008-01-15
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
3D26
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NORWALK P DOMAIN A-TRISACCHARIDE COMPLEX
Descriptor:58 kd capsid protein, N-ACETYL-D-GALACTOSAMINE, BETA-D-GALACTOSE, ...
Authors:Hegde, R., Bu, W.
Deposit date:2008-05-07
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the receptor binding specificity of Norwalk virus.
J.Virol., 82, 2008
5VKI
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CRYSTAL STRUCTURE OF P[19] ROTAVIRUS VP8* COMPLEXED WITH MUCIN CORE 2
Descriptor:Outer capsid protein VP4, SULFATE ION, GLYCEROL, ...
Authors:Xu, S., Liu, Y., Woodruff, A., Zhong, W., Jiang, X., Kennedy, M.A.
Deposit date:2017-04-21
Release date:2017-11-08
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
5VKS
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CRYSTAL STRUCTURE OF P[19] ROTAVIRUS VP8* COMPLEXED WITH LNFPI
Descriptor:Outer capsid protein VP4, SULFATE ION, GLYCEROL, ...
Authors:Xu, S., Liu, Y., Woodruff, A., Zhong, W., Jiang, X., Kennedy, M.A.
Deposit date:2017-04-22
Release date:2017-11-08
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
3U15
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STRUCTURE OF HDMX WITH DIMER INDUCING INDOLYL HYDANTOIN RO-2443
Descriptor:Protein Mdm4, (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione, SULFATE ION
Authors:Lukacs, C.M., Janson, C.A., Graves, B.J.
Deposit date:2011-09-29
Release date:2012-06-27
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VBG
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STRUCTURE OF HDM2 WITH DIMER INDUCING INDOLYL HYDANTOIN RO-2443
Descriptor:E3 ubiquitin-protein ligase Mdm2, (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione
Authors:Lukacs, C.M., Janson, C.A., Graves, B.J.
Deposit date:2012-01-02
Release date:2012-06-27
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Proc.Natl.Acad.Sci.USA, 109, 2012
4J74
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THE 1.2A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH RO0503918 - A NUTLIN FRAGMENT
Descriptor:E3 ubiquitin-protein ligase Mdm2, (4S,5R)-4,5-bis(4-chlorophenyl)-2-methyl-4,5-dihydro-1H-imidazole, SULFATE ION
Authors:Janson, C., Lukacs, C., Kammlott, U., Graves, B.
Deposit date:2013-02-12
Release date:2013-08-07
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013
4J7D
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THE 1.25A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH A NUTLIN FRAGMENT, RO5045331
Descriptor:E3 ubiquitin-protein ligase Mdm2, (4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole, SULFATE ION
Authors:Janson, C., Lukacs, C., Graves, B.
Deposit date:2013-02-13
Release date:2013-08-07
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013
4J7E
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THE 1.63A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH A NUTLIN FRAGMENT, RO5524529
Descriptor:E3 ubiquitin-protein ligase Mdm2, [(4S,5R)-4,5-bis(4-chlorophenyl)-2,4,5-trimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone, SULFATE ION
Authors:Janson, C., Lukacs, C., Graves, B.
Deposit date:2013-02-13
Release date:2013-08-07
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett, 4, 2013
4JRG
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THE 1.9A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH RO5313109 - A PYRROLIDINE MDM2 INHIBITOR
Descriptor:E3 ubiquitin-protein ligase Mdm2, (3R,4R,5S)-3-(3-chlorophenyl)-4-(4-chlorophenyl)-4-cyano-N-[(3S)-3,4-dihydroxybutyl]-5-(2,2-dimethylpropyl)-D-prolinamide
Authors:Graves, B.J., Janson, C.A., Lukacs, C.
Deposit date:2013-03-21
Release date:2013-07-24
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of RG7388, a Potent and Selective p53-MDM2 Inhibitor in Clinical Development.
J.Med.Chem., 56, 2013