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4VUB
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BU of 4vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM ESCHERICHIA COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-10-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1BIR
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BU of 1bir by Molmil
RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Doumen, J, Gonciarz, M, Zegers, I, Loris, R, Wyns, L, Steyaert, J.
Deposit date:1996-01-04
Release date:1996-08-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
1BZQ
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BU of 1bzq by Molmil
COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A
Descriptor: PHOSPHATE ION, PROTEIN (ANTIBODY CAB-RN05), PROTEIN (RNASE A)
Authors:Decanniere, K, Desmyter, A, Gahroudhi, M, Lauwereys, M, Muyldermans, S, Wyns, L.
Deposit date:1998-11-03
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.
Structure Fold.Des., 7, 1999
5GSP
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BU of 5gsp by Molmil
RIBONUCLEASE T1/3'-GMP, 9 WEEKS
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-09
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
1APN
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BU of 1apn by Molmil
THE CRYSTALLOGRAPHIC STRUCTURE OF METAL-FREE CONCANAVALIN A AT 2.5 ANGSTROMS RESOLUTION
Descriptor: CONCANAVALIN A
Authors:Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
Deposit date:1995-07-28
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic structure of metal-free concanavalin A at 2.5 A resolution.
Proteins, 23, 1995
6GSP
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BU of 6gsp by Molmil
RIBONUCLEASE T1/3'-GMP, 15 WEEKS
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-09
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
4I0C
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BU of 4i0c by Molmil
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
Descriptor: CHLORIDE ION, GLYCEROL, Lysozyme C, ...
Authors:De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M.
Deposit date:2012-11-16
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
3VUB
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BU of 3vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
7GSP
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BU of 7gsp by Molmil
RIBONUCLEASE T1/2',3'-CGPS, NON-PRODUCTIVE
Descriptor: GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, PHOSPHATE ION, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-10
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
2VUB
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BU of 2vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-21
Release date:1998-06-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
4GSP
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BU of 4gsp by Molmil
RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS
Descriptor: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ...
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-02
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
1G8W
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BU of 1g8w by Molmil
IMPROVED STRUCTURE OF PHYTOHEMAGGLUTININ-L FROM THE KIDNEY BEAN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCOAGGLUTINATING PHYTOHEMAGGLUTININ, ...
Authors:Buts, L, Hamelryck, T.W, Dao-Thi, M, Loris, R, Wyns, L, Etzler, M.E.
Deposit date:2000-11-21
Release date:2000-12-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus.
J.Mol.Biol., 309, 2001
1G7Y
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BU of 1g7y by Molmil
THE CRYSTAL STRUCTURE OF THE 58KD VEGETATIVE LECTIN FROM THE TROPICAL LEGUME DOLICHOS BIFLORUS
Descriptor: CALCIUM ION, MANGANESE (II) ION, STEM/LEAF LECTIN DB58, ...
Authors:Buts, L, Hamelryck, T.W, Loris, R, Dao-Thi, M.-H, Wyns, L, Etzler, M.E.
Deposit date:2000-11-15
Release date:2000-11-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus.
J.Mol.Biol., 309, 2001
2VCO
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BU of 2vco by Molmil
Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope
Descriptor: NICKEL (II) ION, PROTEIN FIMH, SULFATE ION, ...
Authors:Wellens, A, Garofalo, C, Nguyen, H, Wyns, L, De Greve, H, Hultgren, S.J, Bouckaert, J.
Deposit date:2007-09-26
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the Fimh-Oligomannose-3 Complex.
Plos One, 3, 2008
2X89
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BU of 2x89 by Molmil
Structure of the Beta2_microglobulin involved in amyloidogenesis
Descriptor: ANTIBODY, BETA-2-MICROGLOBULIN
Authors:Domanska, K, Srinivasan, V, Vanderhaegen, S, Pardon, E, Marquez, J.A, Bellotti, V, Wyns, L, Steyaert, J.
Deposit date:2010-03-07
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Atomic Structure of a Nanobody-Trapped Domain-Swapped Dimer of an Amyloidogenic {Beta}2-Microglobulin Variant.
Proc.Natl.Acad.Sci.USA, 108, 2011
2X6M
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BU of 2x6m by Molmil
Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein
Descriptor: ALPHA-SYNUCLEIN PEPTIDE, HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY
Authors:DeGenst, E, Guilliams, T, Wellens, J, O'Day, E.M, Waudby, C.A, Meehan, S, Dumoulin, M, Hsu, S.-T.D, Cremades, N, Verschueren, K.H.G, Pardon, E, Wyns, L, Steyaert, J, Christodoulou, J, Dobson, C.M.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
1X75
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BU of 1x75 by Molmil
CcdB:GyrA14 complex
Descriptor: Cytotoxic protein ccdB, DNA gyrase subunit A
Authors:Dao-Thi, M.H, Van Melderen, L, De Genst, E, Wyns, L, Loris, R.
Deposit date:2004-08-13
Release date:2005-05-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Basis of Gyrase Poisoning by the Addiction Toxin CcdB
J.Mol.Biol., 348, 2005
1YAL
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BU of 1yal by Molmil
CARICA PAPAYA CHYMOPAPAIN AT 1.7 ANGSTROMS RESOLUTION
Descriptor: CHYMOPAPAIN
Authors:Maes, D, Bouckaert, J, Poortmans, F, Wyns, L, Looze, Y.
Deposit date:1996-06-20
Release date:1996-12-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of chymopapain at 1.7 A resolution.
Biochemistry, 35, 1996
1TR7
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BU of 1tr7 by Molmil
FimH adhesin receptor binding domain from uropathogenic E. coli
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, FimH protein, ...
Authors:Bouckaert, J, Berglund, J, Schembri, M, De Genst, E, Cools, L, Wuhrer, M, Hung, C.S, Pinkner, J, Slattegard, R, Zavialov, A, Choudhury, D, Langermann, S, Hultgren, S.J, Wyns, L, Klemm, P, Oscarson, S, Knight, S.D, De Greve, H.
Deposit date:2004-06-21
Release date:2005-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
Mol.Microbiol., 55, 2005
1UWF
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BU of 1uwf by Molmil
1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli
Descriptor: FIMH PROTEIN, GLYCEROL, butyl alpha-D-mannopyranoside
Authors:Bouckaert, J, Berglund, J, Genst, E.D, Cools, L, Hung, C.-S, Wuhrer, M, Zavialov, A, Langermann, S, Hultgren, S, Wyns, L, Oscarson, S, Knight, S.D, De Greve, H.
Deposit date:2004-02-05
Release date:2005-02-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin.
Mol.Microbiol., 55, 2005
1VUB
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BU of 1vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
3F6L
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BU of 3f6l by Molmil
Structure of the F4 fimbrial chaperone FaeE
Descriptor: Chaperone protein faeE
Authors:Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
Deposit date:2008-11-06
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
3F6I
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BU of 3f6i by Molmil
Structure of the SeMet labeled F4 fibrial chaperone FaeE
Descriptor: Chaperone protein faeE
Authors:Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
Deposit date:2008-11-06
Release date:2009-05-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.788 Å)
Cite:The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
3F65
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The F4 fimbrial chaperone FaeE does not self-cap its interactive surfaces
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Chaperone protein faeE, PHOSPHATE ION
Authors:Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
Deposit date:2008-11-05
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
1LEM
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BU of 1lem by Molmil
THE MONOSACCHARIDE BINDING SITE OF LENTIL LECTIN: AN X-RAY AND MOLECULAR MODELLING STUDY
Descriptor: CALCIUM ION, LECTIN, MANGANESE (II) ION, ...
Authors:Loris, R, Wyns, L.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The monosaccharide binding site of lentil lectin: an X-ray and molecular modelling study.
Glycoconj.J., 11, 1994

217705

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