Author results

1DB1
  • Download 1db1
  • View 1db1
Molmil generated image of 1db1
CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D
Descriptor:VITAMIN D NUCLEAR RECEPTOR, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
Authors:Rochel, N., Wurtz, J.M., Mitschler, A., Klaholz, B., Moras, D.
Deposit date:1999-11-02
Release date:2000-01-31
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
Mol.Cell, 5, 2000
1DKF
  • Download 1dkf
  • View 1dkf
Molmil generated image of 1dkf
CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS
Descriptor:PROTEIN (RETINOID X RECEPTOR-ALPHA), PROTEIN (RETINOIC ACID RECEPTOR-ALPHA), OLEIC ACID, ...
Authors:Bourguet, W., Vivat, V., Wurtz, J.M., Chambon, P., Gronemeyer, H., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:1999-12-07
Release date:2000-04-19
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Mol.Cell, 5, 2000
1IE8
  • Download 1ie8
  • View 1ie8
Molmil generated image of 1ie8
CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D LIGAND BINDING DOMAIN BOUND TO KH1060
Descriptor:VITAMIN D3 RECEPTOR, 5-(2-{1-[1-(4-ETHYL-4-HYDROXY-HEXYLOXY)-ETHYL]-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE}-ETHYLIDENE)-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
Authors:Tocchini-Valentini, G., Rochel, N., Wurtz, J.M., Mitschler, A., Moras, D.
Deposit date:2001-04-09
Release date:2001-05-16
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
Proc.Natl.Acad.Sci.USA, 98, 2001
1IE9
  • Download 1ie9
  • View 1ie9
Molmil generated image of 1ie9
CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D LIGAND BINDING DOMAIN BOUND TO MC1288
Descriptor:VITAMIN D3 RECEPTOR, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
Authors:Tocchini-Valentini, G., Rochel, N., Wurtz, J.M., Mitschler, A., Moras, D.
Deposit date:2001-04-09
Release date:2001-05-16
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K4W
  • Download 1k4w
  • View 1k4w
Molmil generated image of 1k4w
X-RAY STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR ROR BETA LIGAND-BINDING DOMAIN IN THE ACTIVE CONFORMATION
Descriptor:Nuclear receptor ROR-beta, steroid receptor coactivator-1, STEARIC ACID
Authors:Stehlin, C., Wurtz, J.M., Steinmetz, A., Greiner, E., Schuele, R., Moras, D., Renaud, J.P.
Deposit date:2001-10-09
Release date:2002-04-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
EMBO J., 20, 2001
1QKT
  • Download 1qkt
  • View 1qkt
Molmil generated image of 1qkt
MUTANT ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL
Descriptor:ESTRADIOL RECEPTOR, ESTRADIOL
Authors:Ruff, M., Gangloff, M., Eiler, S., Duclaud, S., Wurtz, J.M., Moras, D.
Deposit date:1999-08-05
Release date:2000-08-18
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Mutant Heralpha Ligand- Binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism
J.Biol.Chem., 276, 2001
1QKU
  • Download 1qku
  • View 1qku
Molmil generated image of 1qku
WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL
Descriptor:ESTRADIOL RECEPTOR, ESTRADIOL
Authors:Ruff, M., Gangloff, M., Eiler, S., Duclaud, S., Wurtz, J.M., Moras, D.
Deposit date:1999-08-05
Release date:2000-08-18
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism.
J. Biol. Chem., 276, 2001
1S0Z
  • Download 1s0z
  • View 1s0z
Molmil generated image of 1s0z
CRYSTAL STRUCTURE OF THE VDR LBD COMPLEXED TO SEOCALCITOL.
Descriptor:Vitamin D3 receptor, SEOCALCITOL
Authors:Tocchini-Valentini, G., Rochel, N., Wurtz, J.M., Moras, D.
Deposit date:2004-01-05
Release date:2004-04-13
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
1S19
  • Download 1s19
  • View 1s19
Molmil generated image of 1s19
CRYSTAL STRUCTURE OF VDR LIGAND BINDING DOMAIN COMPLEXED TO CALCIPOTRIOL.
Descriptor:Vitamin D3 receptor, CALCIPOTRIOL
Authors:Tocchini-Valentini, G., Rochel, N., Wurtz, J.M., Moras, D.
Deposit date:2004-01-06
Release date:2004-04-13
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
4C03
  • Download 4c03
  • View 4c03
Molmil generated image of 4c03
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 REDUCED
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C04
  • Download 4c04
  • View 4c04
Molmil generated image of 4c04
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH INHIBITOR
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C05
  • Download 4c05
  • View 4c05
Molmil generated image of 4c05
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH SAH
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C06
  • Download 4c06
  • View 4c06
Molmil generated image of 4c06
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH MGCL2
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, MAGNESIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C07
  • Download 4c07
  • View 4c07
Molmil generated image of 4c07
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH CACL2 AT 1.5 ANGSTROMS
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, CALCIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C08
  • Download 4c08
  • View 4c08
Molmil generated image of 4c08
CRYSTAL STRUCTURE OF M. MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE PRMT6 WITH CACL2 AT 1.34 ANGSTROMS
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 6, PENTAETHYLENE GLYCOL, CALCIUM ION
Authors:Bonnefond, L., Cura, V., Troffer-Charlier, N., Mailliot, J., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-07-31
Release date:2014-07-30
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.338 Å)
Cite:Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
4C4A
  • Download 4c4a
  • View 4c4a
Molmil generated image of 4c4a
CRYSTAL STRUCTURE OF MOUSE PROTEIN ARGININE METHYLTRANSFERASE 7 IN COMPLEX WITH SAH
Descriptor:PROTEIN ARGININE N-METHYLTRANSFERASE 7, S-ADENOSYL-L-HOMOCYSTEINE, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, ...
Authors:Cura, V., Troffer-Charlier, N., Bonnefond, L., Wurtz, J.M., Cavarelli, J.
Deposit date:2013-09-02
Release date:2014-07-02
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insight Into Arginine Methylation by the Mouse Protein Arginine Methyltransferase 7: A Zinc Finger Freezes the Mimic of the Dimeric State Into a Single Active Site.
Acta Crystallogr.,Sect.D, 70, 2014
5IH3
  • Download 5ih3
  • View 5ih3
Molmil generated image of 5ih3
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SAH AT 1.8 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-02-29
Release date:2017-03-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
To Be Published
5IS6
  • Download 5is6
  • View 5is6
Molmil generated image of 5is6
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SINEFUNGIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Crystal structure of mouse CARM1 in complex with Sinefungin at 2.0 Angstroms resolution
To Be Published
5IS7
  • Download 5is7
  • View 5is7
Molmil generated image of 5is7
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH DECARBOXYLATED SAH
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of mouse CARM1 in complex with decarboxylated SAH
To Be Published
5IS8
  • Download 5is8
  • View 5is8
Molmil generated image of 5is8
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0271
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.709 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0271
To Be Published
5IS9
  • Download 5is9
  • View 5is9
Molmil generated image of 5is9
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0375
Descriptor:Histone-arginine methyltransferase CARM1, (2S)-2-amino-4-[(3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-1,2,3-triazol-1-yl}propyl){[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}amino]butanoic acid (non-preferred name), 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0375
To Be Published
5ISA
  • Download 5isa
  • View 5isa
Molmil generated image of 5isa
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0401
Descriptor:Histone-arginine methyltransferase CARM1, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azidopropyl)amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0401
To Be Published
5ISB
  • Download 5isb
  • View 5isb
Molmil generated image of 5isb
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0435
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl][(1H-imidazol-4-yl)methyl]amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0435
To Be Published
5ISC
  • Download 5isc
  • View 5isc
Molmil generated image of 5isc
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0491
Descriptor:Histone-arginine methyltransferase CARM1, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0491
To Be Published
5ISD
  • Download 5isd
  • View 5isd
Molmil generated image of 5isd
CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0592
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0592
To Be Published
<12>